Browsing by Author "Gulbahar, MY"

Now showing 1 - 8 of 8

Angiokeratomatous Papilloma Associated With Papillomavirus in a Calf
(Amer Coll vet Pathologist, 2003) Gulbahar, MY; Yuksel, H; Aslan, L
A female 8-month-old Simmental calf was presented with a history of a gradually enlarging mass in the ventral abdominal skin since 4 months of age. The mass was well circumscribed, lightly pigmented, and rough surfaced with many fine fissures and was attached to the skin by a relatively broad pedicle. On cut section, there was a border between the reddish-black stroma and overlying epithelium, including hemorrhagic foci of variable sizes. Histologically, the tumor was papillomatous with angiokeratomatous features and irregular hyperplasia with epidermal rete ridges and dilated vascular channels filled with blood in the superficial dermis. In the epidermis, orthokeratotic hyperkeratosis, variably sized keratohyalin granules, and many koilocytes, some of which had papillomavirus (PV) genus-specific structural antigen-positive nuclei, were also observed. Cells lining the dilated vascular spaces were positive for vimentin and alpha-smooth muscle actin but negative for factor VIII-related antigen, desmin, and PV. The lesion was regarded as an angiokeratomatous papilloma and was similar to other angiomatous lesions.
Assessment of Proliferative Activity by Agnor and Pcna in Prostatic Tissues of Ram Lambs Implanted With Zeranol
(Blackwell Publishing, 2005) Gulbahar, MY; Yuksel, H; Guvenc, T; Okut, H
The aim of this study was to assess cellular proliferation using silver-stained nucleolar organizer regions (AgNOR) and the proliferating cell nuclear antigen (PCNA) in various tissues in the prostate of ram lambs implanted with increasing zeranol doses and to compare the sensitivity of different tissues of lamb prostate to zeranol. Twenty-four Akkaraman lambs were implanted with increasing zeranol doses, including 12 mg (n = 8), 24 mg (n = 8) and 96 mg (n = 8), with eight lambs serving as controls. After 33 days, the prostate tissues of the lambs were stained using AgNOR and PCNA techniques. The prostate tissues were divided into two compartments - the epithelial tissues, including glandular acinus, collecting duct and penile urethra, and the non-epithelia] tissues.. including interstitial tissue and striated muscle. AgNOR dots and PCNA index on each prostatic tissue were counted under a light microscope and were evaluated statistically. AgNOR staining in the treatment groups showed a higher score in the non-epithelial tissues than the epithelial components, whereas the PCNA index was significant in the epithelia] tissues and non-epithelial, tissues had very low. PCNA immunostaining. According to the PCNA index, collecting duct epithelium showed more sensitivity to increasing zeranol doses and according to AgNOR counts, there was no difference of sensitivity to zeranol among tissues of the same origin. Both AgNOR counts and PCNA indexes seem to be valuable proliferating markers for the epithelial components of ram prostate, but PCNA index had no significance in relation to the non-epithelial components in contrast to AgNOR counts. Therefore, the controversial results arising from the combined use of both techniques as proliferating markers for the ram prostate should be considered in further studies.
Congenital Synchronous Adenomas of Meibomian and Moll Glands of the Eyelid in a Calf
(Czech Academy Agricultural Sciences, 2005) Yuksel, H; Gulbahar, MY; Aslan, L
This report describes meibomian adenoma (MA) and moll gland adenoma in a female, 1.5-months-old, crossbreed calf. Macroscopically, the mass was 3 x 1.5 x 0.5 cm in size and 5.35 g in weight; its shape was gray-reddish and it was localized on the right lower eyelid. Microscopically, the mass was composed of lobules of various sizes separated with a septum, which included well-differentiated sebaceous cells and apocrine secretory epithelium, with no an association of both gland types.
The Effects of Fibrin Glue on the Prevention of Adhesion Formation, Leakage and Wound Healing in Dogs
(indian veterinary Journal, 2005) Belge, A; Gulbahar, MY; Bakir, B
Immunohistochemical Detection of Antigen in Lamb Tissues Naturally Infected With Sheeppox Virus
(Blackwell Wissenschafts-verlag Gmbh, 2000) Gulbahar, MY; Cabalar, M; Gul, Y; Icen, H
The present study describes the detection of sheeppox Virus antigen in Various lamb tissues, using an immunohistochemical technique, in sheeppox cases which occurred naturally. Sheeppox viral antigen was detected in the cytoplasm of sheeppox cells and degenerated epithelial cells of die skin, lungs and digestive tract involving typical sheeppox lesions. Nuclear staining was also observed in some typically deformed nuclei of sheeppox cells. The immunostaining of sheeppox virus showed a correlation with the presence of sheeppox cells and degenerated epithelial cells resembling them. additionally, in order to confirm the presence of sheeppox virus in the skin and lung samples, direct electron microscopy was performed and sheeppox virus was only demonstrated in two skin samples.
Mixed Apocrine Sweat Gland Tumor of the Tail in a Cow
(Amer Coll vet Pathologist, 2002) Gulbahar, MY; Alkan, I; Aslan, L; Golen, I
A 4-year-old native-breed cow had a mass with wide areas of ulceration and hemorrhage at the base of the tail at the same level as the vulva. The tumor was 19 X 13 X 11 cm, appeared red-brown, and was firm to hard, with gritty areas apparent on cut surface. Histologically, the tumor mass was composed of multilayered epithelial cells forming glandular structures with occasional apical blebs and rare solidly packed cells in nests. The stroma included fibrous connective tissue, scattered or periglandular sheets of spindle-shaped cells resembling myoepithelium, several cartilaginous formations, and numerous irregular islands of mineralized osteoid, well-formed bone trabeculae lined by osteoblasts, and many osteoclast-like multinucleated giant cells among or near the neoplastic epithelium. Immunohistochemically, the neoplastic epithelium was positive for pan-cytokeratin (AE1/AE2) and cytokeratin 19 but was negative for cytokeratin 18. Spindle-shaped cells were stained with alpha smooth muscle actin (alphaSMA) and to a lesser extent vimentin antibodies. The cells of osteogenic lineage and spindle cells closely associated with the osteoid showed strong immunostaining for vimentin but not for alphaSMA. Immunostaining for neuron-specific enolase and S 100 protein was not observed in any component of the tumor mass. These findings sugguested that the origin of bone formation was undifferentiated mesenchymal cells with osteogenic potential.
Pyothorax Associated With a Mycoplasma Sp and Arcanobacterium Pyogenes in a Kitten
(Australian veterinary Assn, 2002) Gulbahar, MY; Gurturk, K
Pyothorax associated with a Mycoplasma sp and Arcanobacterium pyogenes was diagnosed at necropsy in a 1-month-old female Van kitten. The pleural cavity contained approximately 50 mL of blood-tinged, reddish-brown, nonodourous fluid bilaterally. Gram positive coccobacilli were seen in the exudate from necrotic plaques on the pleurae. Mycoplasma sp and A pyogenes were isolated from a sample of the fluid in the pleural cavity. The concomitant presence of Mycoplasma sp and A pyogenes could be considered another variation on the polymicrobial nature of pyothorax and associated pleural lesions in cats.
Zygomycotic Proventriculitis and Ventriculitis in Ostriches (Struthio Camelus) With Impaction
(Australian veterinary Assn, 2000) Gulbahar, MY; Agaoglu, Z; Biyik, H; Yuksek, N
Three young ostriches (Struthio camelus), aged 4 months, were found to have zygomycotic proventriculitis and ventriculitis associated with impaction. Clinical signs were anorexia, chronic weight loss, weakness and lethargy followed by scant faeces for seven days. Proventriculi and ventriculi from birds were full of masses of hay, grass, leaves and other fibrous materials in combination with sand, gravel and plastic. Erosions and haemorrhagic ulcers of varying number and severity were present in the mucosae of both organs involved. Mucosal lesions were characterized by haemorrhagic necrosis. Throughout the affected mucosae there were 5 to 12 mu-m wide rarely-septated fungal hyphae with non-parallel walls, irregular branching and occasional globoid distentions, typical of Zygomycetes. Zygomycotic proventriculitis and ventriculitis secondary to impaction was diagnosed.