Browsing by Author "Gulec, Mustafa"

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The Association of Depression With Treatment and Disability in Multiple Sclerosis
(Turkish Neuropsychiatry Assoc-turk Noropsikiyatri dernegi, 2012) Tanik, Nermin; Aydin, Adem; Selvi, Yavuz; Gulec, Mustafa; Anlar, Omer; Tombul, Temel
Background: To investigate the effects of disability and specific treatments on depression associated with multiple sclerosis (MS). Methods: Fifty-two patients with MS (patient group) and 48 healthy subjects (control group) participated in the study. While the Beck Depression Inventory (BDI) and the Expanded Disability Status Scale (EDSS) were administered to the patients, healthy controls filled out only the BDI. Psychiatric disorders were determined using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Result: Both groups were found to be identical in their socio-demographic properties. The mean age of onset of MS was 29.1 +/- 1.2 years. There was no difference between males and females in terms of depression. The patient group consisted of patients with: relapsing-remitting MS (71.2%), secondary-progressive MS (13.5%), progressive-relapsing MS (11.5%), and primary-progressive MS (3.8%). A 12-fold increased risk for depression was found among patients with MS. Age, attack number and illness duration did not correlate significantly with risk for development of depression in MS. However, a significant relationship was found between EDSS scores and the risk for the development of depression. Depression was detected in patients using azathioprine (100%), interferon beta-1a SC (88.8%) and in patients not receiving any treatment (78.5%). Conclusion: This study indicates that, disability is an important risk factor for the development of depression, irrespective of the treatment modality. (Archives of Neuropsychiatry 2012; 49: 300-303)
Benefits of Submucous Resection on Sleep Quality, Daytime and Dream Anxiety in Patients With Nasal Septal Deviation
(Springer London Ltd, 2013) Gulec, Tezay Cakin; Yoruk, Ozgur; Gulec, Mustafa; Selvi, Yavuz; Boysan, Murat; Oral, Elif; Mazlumoglu, Muhammet R.
The aim of this report was to assess the frequency of poor sleep quality, daytime and dream anxiety and their response to subsequent surgical treatment for a representative group of 68 patients with nasal septum deviation. Nasal airflows and airway resistances were measured using rhinomanometry and the participants were also asked to fill in Pittsburgh Sleep Quality Index, Beck Anxiety Inventory, and Van Dream Anxiety Scale directly before the submucous resection without turbinectomy and 2 months later. Repeated measure analyses of variance models showed that patients reported significantly lower scores of poor sleep quality, daytime anxiety, and as well as dream anxiety after surgical treatment (P < 0.01). Nasal septal surgery might have beneficial effects on sleep variables in patients with deviation.
Cerebellar Cognitive Affective Syndrome: a Case Report
(Kure Iletisim Grubu A S, 2008) Besiroglu, Lutfullah; Gulec, Mustafa; Kiran, Songul Gundogdu; Polat, Nermin
Although the role of the cerebellum on motor control has been well recognized in studies of functional neuroanatomy, the influence of the cerebellum on cognition and emotion has been neglected until recent years. In the last decades studies that have described the role of the cerebellum on cognitive functions and emotion have been published. In patients with impaired executive dysfunction and visuo-spatial cognition, personality changes, affective symptoms and linguistic difficulties due to different cerebellar lesions, this clinical entity was described as Cerebellar Cognitive Affective Syndrome. In this paper, we present a case with Cerebellar Cognitive Affective Syndrome, and with neuroradiological evidence of a chronic cerebellar lesion.
Childhood Trauma, Depression, and Sleep Quality and Their Association With Psychotic Symptoms and Suicidality in Schizophrenia
(Elsevier Ireland Ltd, 2017) Kilicaslan, Esin Evren; Esen, Asli Tugba; Kasal, Meltem Izci; Ozelci, Erdal; Boysan, Murat; Gulec, Mustafa
This study involved the examination of the relationship between childhood trauma and both psychotic symptoms and suicidality in patients with schizophrenia after controlling for the possible confounding factors, such as clinical features, depression, and sleep quality. The Childhood Trauma Questionnaire-Short Form, Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), Pittsburgh Sleep Quality Index (PSQI), and the suicidality subscale of Mini-International Neuropsychiatric Interview (MINI) were administered to 199 patients with schizophrenia. We used sequential multiple stepwise regression analyses in which positive symptoms, negative symptoms, overall psychopathology, total symptoms of schizophrenia, and suicidality were dependent variables. Depressive symptomatology and childhood physical abuse significantly contributed to positive, negative, general psychopathology, and global schizophrenia symptomatology. Interestingly, general psychopathology scores were negatively associated with childhood physical neglect. Also, subjective sleep quality significantly contributed to positive schizophrenia symptoms. Although prior suicide attempts and depression were significant antecedents of suicidal ideation, no association between suicidality and both childhood trauma and sleep was found. Childhood physical abuse could have an impact on psychopathology in schizophrenia. In addition to childhood trauma, depression, sleep disturbances, and clinical features should be considered and inquired about in the course of clinical care of schizophrenia patients.
Chronotype Effects on General Well-Being and Psychopathology Levels in Healthy Young Adults
(Taylor & Francis Ltd, 2013) Gulec, Mustafa; Selvi, Yavuz; Boysan, Murat; Aydin, Adem; Oral, Elif; Aydin, Esat Fahri
Variations in diurnal preferences for activity and sleep have long been classified as morning and evening chronotypes. Although morning and evening-types do not differ in sleep architecture, earlier studies have revealed the association between eveningness and psychopathology. However, most of these works had been conducted only with patient samples. Additionally, previous research has also discovered that morning-types have a healthier lifestyle than evening-types. Therefore, the aim of the present study was to assess the associations between chronotypes and general well-being and psychopathology levels in practically healthy young adults, whose physical and mental health were both examined precisely prior to the research, for the first time in the literature. We found that morning-type individuals have significantly better health conditions than evening-types. And, participants exhibiting a tendency to evening-type were more prone to develop psychological symptoms than subjects exhibiting morning-type chronobiological characteristics. Mental health professionals should be aware that eveningness may be a risk factor for mental and physical health even in currently well young adults.
Clark-beck Obsesyon-kompulsiyon Ölçeği’nin Türk Toplumunda Psikometrik Özellikleri
(2007) Gulec, Mustafa; Ağargün, Mehmet Yücel; Beşiroğlu, Lütfullah; Eryonucu, Buket; Boysan, Murat
Amaç: Bu çalışmada obsesif kompulsif belirtileri sıklık ve şiddet açısından değerlendirmek üzere geliştirilmiş olan Clark-Beck Obsesyon-Kompulsiyon Ölçeği’nin (CBOKÖ) psikometrik özelliklerinin araştırılması amaçlandı. Yöntem: Obsesif kompulsif bozukluk (OKB) tanısı konmuş 52 hasta, majör depresyonu olan 36 hasta ve OKB dışında başka bir anksiyete bozukluğu olan 32 hasta, 278 öğrenci ve 75 sağlıklı erişkin denek örneklem grubunu oluşturdu. Ölçeğin iç tutarlılığı, test-tekrar test güvenilirliği, eş zaman ve ayırt edici geçerliliği araştırıldı. Sonuçlar: Cronbach α katsayısı obsesyon, kompulsiyon ve toplam puan için tüm örneklemde sırasıyla 0.86, 0.83 ve 0.91 olarak bulundu. İki ayrı zaman diliminden elde edilen puanlar arasındaki bağıntı katsayıları obsesyon puanı için 0.81 (p<0.001), kompulsiyon için 0.85 (p<0.001) ve toplam puan için 0.85 (p<0.001) olarak hesaplandı. OKB olan grubun obsesyon, kompulsiyon ve toplam puanları tüm gruplardan anlamlı olarak yüksek bulundu. Hem OKB grubunda, hem de sağlıklı kişilerde CBOKÖ obsesyon, kompulsiyon ve toplam puanları obsesif kompulsif belirtileri ölçen diğer ölçeklerle (Yale-Brown Obsesyon Kompulsiyon Ölçeği ve Padua Envanteri) anlamlı derecede bağıntı göstermiştir. Tartışma: Sonuçlar, CBOKÖ’nin Türk örnekleminde obsesif-kompulsif belirtilerin değerlendirilmesinde güvenilir ve geçerli bir ölçek olduğunu göstermektedir. (Anadolu Psikiyatri Dergisi 2007; 8:197-205)
Comparison of Dream Anxiety and Subjective Sleep Quality Between Chronotypes
(Springer Japan Kk, 2012) Selvi, Yavuz; Aydin, Adem; Gulec, Mustafa; Boysan, Murat; Besiroglu, Lutfullah; Ozdemir, Pinar Guzel; Kilic, Sultan
Morning and evening-type individuals differ on a number of psychological and biological variables. In this study, we aimed to investigate the relationship between sleep quality, dream anxiety, and chronotypes. A sample of 264 university students, aged between 17 and 26 years, completed the MorningnessEveningness Questionnaire, the Pittsburgh Sleep Quality Index, and the Van Dream Anxiety Scale for assessing nightmare frequency and the dream anxiety caused by frightening dreams. Main findings indicated that evening-type individuals were significantly more likely to suffer from poor sleep quality, daytime dysfunction, nightmares, and nightmare-related disturbances as compared to either intermediate- or morning-type individuals. Previous studies have pointed out the possible connections of irregular sleepwake habits and circadian dysregulation with a tendency to reveal eveningness chronotypical characteristics. Current findings suggest that evening-type individuals are more prone to experience psychologically deteriorating nightmares and sleep-related anxiety. Poor sleep quality is also a significant antecedent of dream anxiety after controlling for age and gender.
Development of a Psychometric Instrument Based on the Inference-Based Approach To Obsessive-Compulsive Disorder: the Obsessional Probabilistic Inference Scale
(Turkish Neuropsychiatry Assoc-turk Noropsikiyatri dernegi, 2014) Gulec, Mustafa; Deveci, Erdem; Besiroglu, Lutfullah; Boysan, Murat; Kalafat, Temel; Oral, Elif
Introduction: The current article addresses the validation of the construct of obsessional probabilistic inference in clinical and non-clinical samples. Obsessional probabilistic inference or obsessional doubt refers to a type of inferential process resulting in the belief that a state of affairs "maybe" causes development of a maladaptive cognitive coping style in terms of obsessing. Methods: The latent structure of the Obsessional Probabilistic Inference Scale (OPIS) was evaluated with confirmatory factor analysis. Results: Explanatory and confirmatory factor analyses indicated that a one-factor solution was satisfactory for the instrument, assessing a unidimensional psychological construct. The OPIS was shown to have high internal consistency in all samples, as well as temporal stability, relying on predominantly non-clinical individuals. The scale exhibited high convergent validity and successfully discriminated patients with obsessive-compulsive disorder from both depressive patients and controls. Conclusion: The findings replicated and extended the role of reasoning process in the development and maintenance of obsessive compulsive symptoms. The results are discussed in regard to assumptions of the inference-based approach to obsessive-compulsive disorder.
Diagnostic Performance of the Turkish Version of the Vancouver Obsessional Compulsive Inventory (Voci) Versus Padua Inventory-Revised (pi-R): a Validation Study
(Kure Iletisim Grubu A S, 2015) Boysan, Murat; Gulec, Mustafa; Deveci, Erdem; Barut, Yasar
Objective: The Vancouver Obsessional Compulsive Inventory (VOCI) is a self-report inventory developed to assess a wide range of obsessive-compulsive symptoms, including contamination (12 items), checking (6 items), obsessions (12 items), hoarding (7 items), just right (12 items), and indecisiveness (6 items). The English version of the VOCI has been shown to be a promising psychometric instrument, as have its French, Italian, and Spanish versions. The aim of this study was to investigate psychometric properties of the Turkish version of the VOCI in clinical and non-clinical samples. Method: A questionnaire package including the VOCI, Padua Inventory-Revised (PI-R), Obsessional Beliefs Questionnaire (OBQ), and Beck Depression Inventory (BDI) was administered to volunteer undergraduates (n=365) and patients with obsessive-compulsive disorder (OCD) (n=46). Psychometric analyses were run to assess reliability and validity of the Turkish version of the VOCI. We converged a confirmatory factor analysis to test the factor structure. We also performed a receiver operating characteristic (ROC) analysis to determine cut-off scores and compared the diagnostic performance of the VOCI and PI-R. Convergent and discriminant validity of the VOCI were assessed through Pearson product-moment correlation coefficients. Internal consistency and temporal reliability were computed. Results: Confirmatory factor analysis replicated the original six-factor structure. The maximum likelihood factor loading estimates were higher than 0.40. OCD patients scored significantly higher than control subjects on the contamination, checking, obsessions, things just right, and indecisiveness subscales of the VOCI but not on the hoarding subscale. The global VOCI scores highly correlated with the PI-R (r=0.89); correlation between the contamination subscale of the VOCI and washing subscale of the PI-R was r=0.88; correlation between the checking subscales of both screening tools was r=0.83; correlation between the just right subscale of the VOCI and precision subscale of the PI-R was r=0.71; and correlation between the obsession subscale of the VOCI and rumination subscale of the PI-R was r=0.71. Divergent validity of the VOCI was also high, so that correlations of the total and subscales of the VOCI with the total and subscales of the PI-R were from r=0.25 to a high of r=0.41; therefore, it can be said that the coefficients ranged from weak to moderate. These correlation coefficients were indicative of good convergent and divergent validity. Internal consistency of the VOCI global was 0.97, and that of the VOCI subscales ranged between 0.82 and 0.92 in the overall sample. Cronbach's Alphas of the VOCI subscales in the OCD group were between 0.73 and 0.88, and in the control group between 0.84 and 0.92. Fifteen-day test-retest intra-correlations for total scores of the VOCI were 0.75; for the subscales they ranged from 0.68 up to 0.88. The ROC analysis demonstrated a moderate diagnostic performance for the VOCI cut-off score of 87.5 with a sensitivity of 0.74 and a specificity of 0.73 immediately comparable to the PI-R cut-off point of 67.5. Conclusion: The VOCI had good internal consistency, test-retest reliability, convergent and discriminant validity. It is concluded that the Turkish version of the VOCI has sound psychometric properties. Further studies are needed to develop psychometric tools with stronger diagnostic performance for OCD assessment.
The Impact of Obsessive Beliefs on Pharmacological Treatment Response in Patients With Obsessive-Compulsive Disorder
(Taylor & Francis Ltd, 2011) Selvi, Yavuz; Atli, Abdullah; Besiroglu, Lutfullah; Aydin, Adem; Gulec, Mustafa
Objective. The present study examined whether obsessive beliefs change over time in the OCD patients receiving selective serotonin reuptake inhibitors (SSRIs) and the impact of obsessive beliefs in treatment response. Methods. In the first part of a two-stage study comparing the efficacy of antipsychotics as augmenting agent in SSRI-resistant OCD patients, 57 patients were interviewed with the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), Hamilton Depression Rating Scale (HDRS) and Obsessive Beliefs Questionnaire-44 (OBQ-44) before and after 12-week of SSRI treatment period. Results. All OBQ-44 subscale scores significantly decreased with SSRI treatment. The mean changes in OBQ-44 Importance and Control of Intrusive Thoughts (I/CT) subscale and HDRS total scores of responders were significantly higher than those of SSRI-resistant patients. The baseline OBQ-44 P/C and Y-BOCS obsession subscale scores significantly predicted the treatment resistance in a logistic regression model. Conclusions. The alleviation of negative mood by SSRIs may help the sufferer to disengage from dysfunctional appraisals. Since individuals with highly obsessive beliefs about P/C are more likely to be resistant to SSRI treatment, the treatment of OCD can be made more effective when focusing on altering appraisals about P/C.
Mood Changes After Sleep Deprivation in Morningness-Eveningness Chronotypes in Healthy Individuals
(Blackwell Publishing, 2007) Selvi, Yavuz; Gulec, Mustafa; Agargun, Mehmet Yucel; Besiroglu, Lutfullah
Inconsistent results have been found in the studies evaluating the effect of both total and partial sleep deprivation (SD) on mood in healthy subjects and a few variables have been analyzed as possible predictors. In the present study, we examined whether circadian preference modifies the effect of SD on mood changes in healthy subjects. Sample consisted of 60 healthy volunteers (including 30 morningness and 30 eveningness subjects). Then, the two groups were again divided into two groups for two SD procedures. Fifteen morningness and 15 eveningness chronotypes were total sleep deprived and 15 morningness and 15 eveningness subjects were partial sleep deprived. The mood changes were evaluated before and after SD using Profile of Mood States. Two main results were obtained from our study: a significant increase in depression subscale in morningness chronotypes and a significant decrease in depression subscale score after total SD (TSD) in eveningness chronotypes. The changes in depression-dejection scores of eveningness chronotypes after total (P < 0.01) and partial SD (P < 0.01) were significantly different from changes in morningness chronotypes after TSD. Our results suggest that the effect of SID on mood in normal subjects is related to their circadian preferences. The morningness or eveningness characteristics of the shift workers have significant impact on their mood states. Therefore, adjusting the work schedule with the morningness and eveningness characteristics of the workers may improve their mood alterations.
Nightmares, Suicide Attempts, and Melancholic Features in Patients With Unipolar Major Depression
(Elsevier, 2007) Agargun, Mehmet Yucel; Besiroglu, Lutfullah; Cilli, Ali Savas; Gulec, Mustafa; Aydin, Adem; Incl, Rifat; Selvi, Yavuz
Objectives: Recently, there has been a growing interest in the relationship between sleep disturbances and suicidality in major depression. Sleep disturbances are one of the 'modifiable risks' for suicide in major depression. The present study examines whether there is a relationship among nightmares, suicide attempts, and melancholic features in unipolar major depressed patients. Methods: One hundred (49 males and 51 females) depressed patients with melancholic features and 49 (23 males and 26 females) patients without melancholic features were included in the study. All patients were classified as those who attempted suicide at least once during current depressive episode and as those who never attempted. Results: Melancholic attempters had higher rates of nightmares, middle, and terminal insomnia than melancholic non-attempters. There was no significant difference between non-melancholic patients with and without suicidal attempts in terms of the frequency of all types of insomnia and nightmares. Limitations: This study does not have polysomnographic records for steep variables. Conclusions: Feeling worse in the morning than later in the day may be related to the intervening dream content and affect and predict suicidal tendency. Melancholia may be associated with increased risk of suicide attempts due to repetitive and frightening dreams. (c) 2006 Elsevier B.V. All rights reserved.
Obsesif-kompulsif Belirtilerin Değerlendirilmesi: Padua Envanteri’nin Türk Toplumunda Geçerlik ve Güvenilirliği
(2005) Gulec, Mustafa; Eryonucu, Buket; Ağargün, Yücel Mehmet; Selvi, Yavuz; Boysan, Murat; Beşiroğlu, Lütfullah
Amaç: Obsesif-kompulsif belirtilerin dağılım ve şiddetini değerlendiren Padua Envanteri’nin (PE) 60 soruluk özgün ve 41 soruluk uyarlama formunun psikometrik özellikleri araştırıldı. Yöntem: Obsesif kompulsif bozukluk (OKB) tanısı almış 43 hasta, majör depresyonlu 30 hasta ve OKB dışında anksiyete bozukluğu olan 30 hasta, 181 öğrenci ve 76 sağlıklı yetişkin örneklem grubunu oluşturdu. Ölçeğin iç tutarlılığı, test-tekrar test güvenilirliği, faktör yapısı, eş zaman ve ayırt edici geçerliği araştırıldı. Bulgular: PE her iki formunun tüm alt ölçek ve toplam maddeleri yüksek iç tutarlılık ve test-tekrar test güvenilirliği göstermiştir. Faktör analizi ile elde edilen altı faktörlü yapı, PE 41 soruluk form ile büyük oranda benzerlik gösterirken, özgün formun faktör yapısı doğrulanamamıştır. Her iki form için dürtüler alt-ölçeği dışında toplam ve tüm alt-ölçekler, Yale-Brown obsesyon, kompulsiyon ve toplam puanları ile anlamlı bağıntı göstermiştir. Her iki formun alt-ölçek ve toplam puanları OKB hastalarında sağlıklı kontrollerden anlamlı olarak yüksek bulunmuştur. Her iki form için OKB hastalarının toplam, kontrol, temizlik puanları diğer gruplardan anlamlı olarak yüksek bulunurken, dürtüler alt-ölçeği açısından anlamlı bir fark bulunmamıştır. Düşüncelere kapılma alt-ölçeğinde PE kısa formun özgün forma oranla daha iyi ayırt edici geçerliliğe sahip olduğu görülmüştür. Sonuç: Bu sonuçlar, PE’nin Türk örnekleminde güvenilir ve geçerli bir ölçek olduğunu göstermektedir.
Ongoing or Re-Emerging Subjective Insomnia Symptoms After Full/Partial Remission or Recovery of Major Depressive Disorder Mainly With the Selective Serotonin Reuptake Inhibitors and Risk of Relapse or Recurrence: a 52-Week Follow-Up Study
(Elsevier, 2011) Gulec, Mustafa; Selvi, Yavuz; Boysan, Murat; Aydin, Adem; Besiroglu, Lutfullah; Agargun, Mehmet Yucel
Background: Many patients who remit fully/partially or recover from an episode of major depression continue to suffer from sleep problems, mainly insomnia. Our study assesses the frequency and types of ongoing or re-emerging subjective insomnia symptoms and their relationship to subsequent depressive relapse or recurrence in a group of full/partial remitters or recoverers. Method: Sixty patients, 18 to 65 years of age, with current MDD defined using DSM-IV-TR criteria were participated in the study. They began a 24-week course of open-label acute plus continuation phase treatment mainly with SSRIs. Maintenance treatment was not planned for not affecting natural relapse or recurrence rates. All participants were evaluated by CGI-S, BDI, HAMD-17, PSQI, and ISI at weeks 0. 4, 12, 24, and 52. Results: Majority of the participants (83.33%) had subjective sleep disturbance, insomnia prior to relapse or recurrence. Repeated measures ANOVA was used to evaluate changes in scores of depression and sleep scales over time between recurred (N =12) and non-recurred groups (N = 48). Differences between means were calculated with post hoc Bonferroni comparison test. The changes in scores of entire clinical scales over time between recurred and non-recurred groups were statistically significant Limitations: The limitations of this study include the use of a relatively small, mostly young female sample and the lack of an objective sleep measure to corroborate self-report scales. Conclusions: Early recognition and treatment of disturbances of the sleep-wake cycle may be important for treatment and prevention of recurrence of depression. (C) 2011 Elsevier B.V. All rights reserved.
Oxidative Stress in Patients With Primary Insomnia
(Pergamon-elsevier Science Ltd, 2012) Gulec, Mustafa; Ozkol, Halil; Selvi, Yavuz; Tuluce, Yasin; Aydin, Adem; Besiroglu, Lutfullah; Ozdemir, Pinar Guzel
Objective: Many physiological and pathological processes, such as infections, environmental toxins, and ionizing radiation increase bodily concentrations of oxidizing substances, known as free radicals, which lead to neuro-degenerative disorders. Sleep is one of the most important factors contributing to health; however, insomnia is among the most prevalent health complaints. Methods: In this study, for the first time in the literature, we investigated the effects of primary insomnia on certain oxidative stress biomarkers. For this purpose, glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and myeloperoxidase (MPO) activities and levels of reduced glutathione (GSH) and malondialdehyde (MDA) were measured in 30 patients with primary insomnia and 30 healthy volunteers Results: Our results show that the patients with primary insomnia had significantly lower GSH-Px activity and higher MDA levels compared with the controls. Conclusion: These results may indicate the important role of sleep in attenuating oxidative stress. (C) 2012 Elsevier Inc. All rights reserved.
Psychometric Evaluation of the Turkish Language Version of the Profile of Mood States (Poms)
(Yerkure Tanitim & Yayincilik Hizmetleri A S, 2011) Selvi, Yavuz; Gulec, Mustafa; Aydin, Adem; Besiroglu, Lutfullah
Aim: The POMS was developed to assess short-term mood changes and consisted of 65 adjectives and 6 subscales. The purpose of the study was to assess the translation adequacy of a Turkish version of the POMS, and to report the decision-making process of overcoming methodological faults. Method: The English version was translated to Turkish by expert team approach. Factor analysis for construct validation was predominantly used for assessment, in addition to other techniques: back translation, use of bilingual subjects, and correlation with other instruments for concurrent validation. Results: The final 58-item Turkish version has suitable psychometric properties. Our findings, based on data from Turkish participants, replicated the original 6-factor solution ("depression-dejection"-15, "tension-anxiety"-9, "anger-hostility"-12, "confusion-bewilderment"-7, "fatigue-inertia"-7, and "vigor-activity"-8). To achieve an acceptable fit, it was necessary to omit 7 items that did not fit any factor. We verified these results by conducting a confirmatory factor analysis on the validation sample and obtaining comparable fit and comparable factor loadings. The concurrent validity of this form was evidenced by the correlations between scores from the POMS subscales and scores from measures of anxiety and depression. Conclusions: Although the study shows valid psychometric properties, further studies made in various populations are needed to assess the sensitivity of the scale.
Psychometric Properties of the Insomnia Severity Index in Turkish Sample
(Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2010) Boysan, Murat; Gulec, Mustafa; Besiroglu, Lutfullah; Kalafat, Temel
Objective: Prevalence of insomnia was detected approximately one third of normal population in surveys. Research evidence suggests that comorbid sleep problems in patients with psychiatric disorders and health problems are not rare. Therefore, the importance of development and using of the instruments that assess primary and secondary insomnia increases. Insomnia Severity Index (ISI) developed by Morin has translated into various languages and have prevalent use for the research purposes. The aim of the study was to assess psychometric properties of the Insomnia Severity Index in Turkish sample. Methods: Data were collected from 34 patients diagnosed with depression in psychiatry clinics of Yuzuncu Yil University Faculty of Medicine Research Hospital and 258 undergraduate healthy controls. The ISI, the Hamilton Depression Scale (HDS), the Beck Depression Inventory (BDI), and Pittsburgh Sleep Quality Index (PSQI) were administered to the subjects. Concurrent validity was evaluated by calculating correlations between the ISI scores and other psychological variables. Item analyses, inner consistency coefficient and intraclass correlations between two repeated applications in both patient and healthy subjects were calculated. Construct validity was tested by using principal component analysis with varimax rotation and structural equation analysis. Results: Correlations between the instrument and other psychological variables were adequate. Item discriminations were higher than 0.44. Inner consistency of the scale was 0.79. Intraclass correlation at 30-day time interval in depressive patients was 0.65 and at 15-day time interval in 68 healthy controls was 0.82. It was found in factor analyses that Turkish form has a two-factor structure: 'Daily functionality' and 'sleep quality'. Conclusion: The ISI revealed adequate validity and reliability to be used by researchers in Turkish sample. Current results were discussed under the previous findings and concerning theoretical considerations. (Anatolian Journal of Psychiatry 2010; 11:248-252)
Psychometric Properties of the Turkish Version of the Internet Addiction Test (Iat)
(Pergamon-elsevier Science Ltd, 2017) Boysan, Murat; Kuss, Dania J.; Barut, Yasar; Aykose, Nafi; Gulec, Mustafa; Ozdemir, Osman
Objective: Of many instruments developed to assess Internet addiction, the Internet Addiction Test (IAT), an expanded version of the Internet Addiction Diagnostic Questionnaire (IADQ), has been the most widely used scale in English and non-English speaking populations. In this study, our aim was to investigate the psychometric properties of short and expanded versions of the IAT in a Turkish undergraduate sample. Method: Overall, 455 undergraduate students from Turkey aged between 18 and 30 participated in the study (63.53% were females). Explanatory and confirmatory factor analytic procedures investigated factor structures of the IADQ and IAT. The Internet Addiction Scale (IAS), Coping Inventory for Stressful Situations (CISS), Obsessive,Compulsive Inventory Revised (OCI-R) and Dissociative Experiences Scale (DES) were administered to assess convergent and divergent validities of the IADQ and IAT. Internal consistency and 15-day test-retest reliability were computed. Results: In the factorial analytic investigation, we found a unidimensional factor structure for each measure fit the current data best. Significant but weak to moderate correlations of the IADQ and the IAT with the CISS, OCI-R and DES provided empirical evidence for divergent validity, whereas strong associations with the subscales of the IAS pointed to the convergent validity of Young's Internet addiction construct. Internal consistency of the IADQ was weak (alpha = 0.67) and of the IAT was high (alpha = 0.93). Temporal reliability of both instruments was very high (alpha = 0.81 and alpha = 0.87; respectively). Conclusion: The IAT revealed promising and sound psychometric properties in a Turkish sample. (C) 2015 Elsevier Ltd. All rights reserved.
Psychometric Properties of the Turkish Version of the Posttraumatic Cognitions Inventory (Ptci) in a Non-Clinical Sample
(Turkish Neuropsychiatry Assoc-turk Noropsikiyatri dernegi, 2013) Gulec, Mustafa; Kalafat, Temel; Boysan, Murat; Barut, Yasar
Background: Cognitive theories of posttraumatic stress disorder have increasingly been recognised. The Posttraumatic Cognitions Inventory is a promising self-report instrument to assess negative cognitions associated with posttraumatic distress. Method: In this study, we examined the psychometric properties of the Posttraumatic Cognitions Inventory in 653 non-clinical Turkish college students. 185 participants reported having experienced various types of trauma. Results: Confirmatory factor analyses replicated the original three-factor structure without excluding any items. Total and subscale scores of the instrument revealed strong connections with severity of depression, anxiety, and dissociative symptoms. Concurrent validity of the Self-Blame subscale was specific to subtype of trauma. The total and the subscales of the instrument had high internal consistency and adequate temporal stability over a two-week interval with an exception of the Self-Blame subscale. The correlation coefficient between the two applications was extremely low for the subscale. Conclusion: We assume that the Self-Blame subscale fails to perform well among individuals who had experienced an aversive event other than interpersonal trauma. The PTCI revealed adequate reliability and validity in a nonclinical Turkish sample.
Psychotropic Medications Affecting Biological Rhythm
(Yerkure Tanitim & Yayincilik Hizmetleri A S, 2011) Oral, Elif; Ozcan, Halil; Gulec, Mustafa; Selvi, Yavuz; Aydin, Adem
There are many biological rhythms with various time oscillations regulating biological functions in living organisms, mammalians, and humans. Biological rhythms such as circadian, ultradian, and infradian or with longer cycles are independent biological organizations rather than dependent to the external stimulus. Although there is a sustained biological rhythmicity, psychiatric disorders and psychotropic drugs can change this process. The effects of psychotropics on biological rhythmicity can occur via possible neurotransmitter and neuromediator mechanisms within a relatively short time period on the other hand hormonal or genetic mechanisms can impact long term outcome. So far several studies suggested that biological rhythm disturbances play an important role in etiology and course of mood disorders'. Assessment of the possible effects of psychopharmacological agents on biological rhythm is important during the course of mood disorders.