Browsing by Author "Ilhan, Ziya"

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Atık Yapmış Koyunların Süt ve Atık Etus Mide İçeriklerinde Brucella Melitensis'in Kültür ve Polimeraz Zincir Reaksiyonu ile Belirlenmesi
(2006) Ilhan, Ziya; Solmaz, Hasan; Gülhan, Timur; Ekin, İsmail H.; Boynukara, Banur; Aksakal, Abdülbaki
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Biotyping and Serotyping of Mannheimia (Pasteurella) Haemolytica Isolated From Lung Samples of Slaughtered Sheep in the Van Region
(Tubitak Scientific & Technological Research Council Turkey, 2007) Ilhan, Ziya; Keles, Ihsan
A total of 584 lung samples of slaughtered sheep having clinical symptoms of pneumonia were investigated microbiologically. Out of the 584 samples, 66 (11.3%) Mannheimia (Pasteurella) haemolytica strains were isolated on the basis of cultural, morphological and biochemical characteristics. Sixty- six isolates of M. haemolytica were biotyped by carbohydrate fermentation tests and serotyped by coagglutination and indirect haemagglutination (IHA) tests. Out of the 66 M. haemolytica strains, 57 (86.3%) were detected as biotype A, and 9 (13.6%) were biotype T. The 66 M. haemolytica isolates were serotyped as follows by coagglutination test: 13 (19.6%) A2, 11 (16.6%) A1, 9 (13.6%) A6, 7 (10.6%) A9, 4 (6.0%) A5, 4 (6.0%) A7, 4 (6.0%) A12, 3 (4.5%) A8, 1 (1.5%) T4, 1 (1.5%) A13, and 1 (1.5%) T15. Of the M. haemolytica strains, 14 (21.2%) belonged to serotype A2, 11 (16.6%) to serotype A1, 10 (15.1%) to serotype A6, 7 (10.6%) to serotype A9, 4 (6.0%) to serotype A5, 4 (6.0%) to serotype A7, 4 (6.0%) to serotype A12, 4 (6.0%) to serotype A8, 1 (1.5%) to serotype T4, 1 (1.5%) to serotype A13 and 1 (1.5%) to serotype T15 by IHA test. Eight (12.1%) and 5 (7.5%) isolates were unserotyped by coagglutination and IHA tests, respectively. T3, T10, A11, A14 and A16 serotypes were not determined.
Cross-Border Molecular Tracing of Brucellosis in Europe
(Elsevier Sci Ltd, 2012) Gwida, Mayada; Neubauer, Heinrich; Ilhan, Ziya; Schmoock, Gernot; Melzer, Falk; Noeckler, Karsten; Al Dahouk, Sascha
To assess the general impact of endemic countries on the re-emergence of brucellosis in non-endemic regions of the European Union, the genetic fingerprints of Brucella melitensis strains imported to Germany were compared to ovine strains from Turkey in a molecular epidemiological study. Genotyping of 66 Brucella strains (based on Multiple Locus of Variable number of tandem repeats Analysis) isolated from German travellers and Turkish immigrants living in Germany revealed epidemiological concordance with 20 sheep isolates originating from Eastern Anatolia, Turkey. In summary, cross-border molecular tracing confirmed brucellosis being a zoonosis of concern for European public health. (C) 2012 Elsevier Ltd. All rights reserved.
Detection and Comparison of Neuraminidase Activities in Human and Bovine Group B Streptococci
(Wiley-blackwell, 2016) Ekin, Ismail Hakki; Gurturk, Kemal; Ilhan, Ziya; Ekin, Suat; Borum, Ayse Ebru; Arabaci, Cigdem; Yesilova, Abdullah
Human and bovine group B streptococcus (GBS) isolates were serotyped and amounts of released N-acetylneuraminic acid from N-acetylneuraminyl-lactose by extracellular neuraminidase were colorimetrically assessed. According to serotyping by co-agglutination method, 30 of bovine GBS and 43 of human GBS could be serotyped (ST) by monospecific antisera coated with protein A. The remaining GBS strains were designated as nontypeable (NT). The released N-acetylneuraminic acid was determined in 90.9% of bovine GBS and 47.1% of human GBS isolates. The differences between the total bovine and human GBS isolates were statistically significant (p < 0.001). In comparison with detected N-acetylneuraminic acid level in bovine and human groups, significant decrease was observed in the bovine NT group according to increased human NT (p < 0.01) and bovine ST groups (p < 0.01). However, N-acetylneuraminic acid level in bovine ST and bovine total groups significantly (p < 0.001) increased with respect to the human ST group and human total group. Neuraminidase activity was detected more frequently in bovine GBS isolates. Considerable differentiations were observed between typeable and nontypeable isolates.
Detection of Bovine Tuberculosis by Tuberculin Test and Polymerase Chain Reaction in Van, Turkey
(Tubitak Scientific & Technological Research Council Turkey, 2009) Solmaz, Hasan; Ilhan, Ziya; Aksakal, Abdulbaki; Gulhan, Timur; Ekin, Ismail Hakki
aim of this study was to identify the presence and prevalence of bovine tuberculosis in the eastern Anatolian border province of Van and its villages and to collect the preliminary data required for programs for the prevention and control of this zoonotic disease. The tuberculin test was performed on 210 cattle. Nasal swab and milk samples were obtained from the animals tested. Three cattle that had a positive tuberculin test also tested positive for the DNA target, a 580-bp fragment of IS6110 specific for members of the Mycobacterium tuberculosis complex. This fragment was also recovered from milk taken from the third animal tested positive for tuberculin. All the other cattle were negative for bovine tuberculosis on both tuberculin test and PCR assay. The results of the tuberculin test and the PCR were in close correlation with each other. Van is a border province in eastern Anatolia. In the city center and its villages, the prevalence of bovine tuberculosis was estimated as 1.42%.
Detection of Enzyme Activities and Their-Relation To Serotypes of Bovine and Human Group B Streptococci
(Soc General Microbiology, 2015) Ekin, Ismail Hakki; Gurturk, Kemal; Ilhan, Ziya; Arabaci, Cigdem; Gulaydinl, Ozgul
Enzymatic properties of group B streptococci (GBS) serotypes from bovine milk and human routine vaginal specimens were investigated. Out of the 56 human and 66 bovine GBS, 35 and 30 could be classified serologically by a co-agglutination test with type-specific antisera, respectively. Hyaluronidase (HYAL), streptokinase (SK) and protease activities were detected using culture media. HYAL activity was observed mostly in typable human GBS, and serotypes la, lc and II comprised 77.3 % of the typable strains producing HYAL. Bovine GBS serotypes II, III and VII comprised 87.5 % of typable bovine strains exhibiting HYAL activity. SK activity was detected only in three human GBS. Human GBS serotypes la, lc, II, III, VII and almost all typable bovine GBS strains showed protease activity. beta-D-glucosidase activity was frequently observed in human GBS, whereas N-acetyl-beta-D-glucosaminidase activity was mostly detected in non-typable GBS from humans. These results indicate that different GBS serotypes could vary in their virulence properties, and bovine and human GBS isolates could not be differentiated by their enzyme activities. Use of the culture media appeared to be a simple-to-apply and useful method for the detection of extracellular enzyme activity such as HYAL, protease and SK.
Detection of Heat-Stabile and Heat-Labile Enterotoxins of Escherichia Coli Strains Isolated From Healthy Animals
(Medwell online, 2009) Guelhan, Timur; Ilhan, Ziya; Aksakal, Abdulbaki; Solmaz, Hasan
In this study, Escherichia coli strains isolated from feces of 12 various healthy animals (sheep, cow, dog, quail, cattle, ostrich, lamb, gull and chicken, Turkey, cat and pigeon) were examined for heat Stabile enterotoxin (ST) and heat Labile enterotoxin (LT). For this purpose, two commercial kits that E. coli ST EIA was used to determine of ST and VET-RPLA was used to determine of LT. A total of 695 E. coli strains were isolated and identified from 2300 fecal samples. Out of these isolates tested for the presence of ST and LT enterotoxin, 17 isolates (2.4%) were found positive for ST and 13 isolates (1.9%) for LT. E. coli strains isolated from turkey, pigeon, gull and ostrich were found to be negative for ST and LT. As a result, with this study, the enterotoxigenic properties of E. coli strains isolated from animal species such as quail, gull, pigeon and ostrich were examined for the first time in Turkey.
Detection of Seasonal Asymptomatic Dermatophytes in Van Cats
(Springer, 2016) Ilhan, Ziya; Karaca, Mehmet; Ekin, Ismail Hakki; Solmaz, Hasan; Akkan, Hasan Altan; Tutuncu, Mehmet
The Van cat is a domestic landrace found in the Van province of eastern Turkey. In this study, we aimed to determine the seasonal carriage of dermatophytes in Van cats without clinical lesions. A total of 264 hair specimens were collected from clinically healthy cats in and around the Van Province. Of these samples, 30.3% were obtained in spring, 30.6% in summer, 16.6% in autumn, and 22.3% in winter; 45.1% of samples were from male cats and the rest from female ones. Of the studied cats, 118 were younger than 1 year, 78 were 1-3 years old, and 68 were older than 3 years. The specimens were subjected to direct microscopic examination with 15% potassium hydroxide and cultured on Sabouraud dextrose agar and dermatophyte test medium supplemented with cycloheximide and chloramphenicol. Dermatophyte identification was carried out based on macroscopic and microscopic colony morphology, urease activities, in vitro hair perforation test, growth at 37 degrees C, and pigmentation on corn meal agar. Dermatophytes were isolated from 19 (7.1%) of the 264 specimens examined. The most frequently isolated fungi were Trichophyton terrestre (4.1%), followed by Microsporum gypseum (1.1%), M. nanum (1.1%), and T. mentagrophytes (0.7%), and these fungi may represent a health risk for humans in contact with clinically healthy Van cats. M. canis was not isolated from any of the specimens. Our results show no significant (p>0.05) association between carriage of dermatophytes and the gender of cats. The carriage rate of dermatophytes was high in spring and winter, and the only possible risk factor for infection was age of the animal. (C) 2015 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda.
Dot Immunobinding Assay Ve Rose Bengal Lam Aglütinasyon Testleri Ile Koyun Kan Serumlarinda Brucella Antikorlarinin Tespiti
(1997) Ilhan, Ziya; Göktürk, Kemal; Erganiş, Osman
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Hypericum Perforatum L. (St. John's Wort) in Broilers Diet Improve Growth Performance, Intestinal Microflora and Immunity
(Elsevier, 2024) Ilhan, Ziya; Zengin, Muhittin; Bacaksiz, Oguz Koray; Demir, Erguen; Ekin, Ismail Hakki; Azman, Mehmet Ali
Hypericum perforatum L. (St. John's Wort) extract (HPE), powdered H. perforatum (PHP), and selenium (Se) on growth, intestinal flora, and immunity of broiler chicks were investigated. In total, 504 one-day-old broiler chicks were randomly allocated into 6 dietary treatments, which were then denoted as negative control (NC) group (basal diet), containing organic Se 0.2% in the starter and grower period as positive control (PC), containing 1% PHP in the starter and grower period, and HPE I, HPE II, and HPE III groups containing respectively, 1.5, 3.0, and 4.5 mL / kg HPE in the starter and grower period. The results on performance showed that a significant (P < 0.05) higher body weight of chickens in the HPE III group was observed when compared with that of the NC and PHP groups. Although average daily weight gain and feed intake are significant in the HPE III group, the difference in terms of total feed conversion rate was insignificant (P > 0.05). The liver weights in PC and HPE III were lower compared to HPE I (P < 0.05). The difference in total lactic acid bacteria count (TLABC) between the NC group and all HPE groups was found to be significant (P < 0.05), in addition to TLABC was higher in the HPE III group than other groups (P = 0.001). The highest serum antibody titers to the Newcastle disease vaccine were determined in the HPE III group on the 24th, 35th, and 42nd days of age. IL-1B and IL-6 were found to be insignificant between the groups in chickens (P > 0.05). TNF-alpha in the HPE III group was greatly increased than the other groups and significant compared to the NC and HPE I groups (P = 0.018). In conclusion, 4.5 mL / kg HPE, which has a low production cost and is easy to extract and without causing environmental problems, varied significantly in their impact on growth performance, intestinal microflora, and immunity of growing broilers.
In Vitro Antimicrobial Susceptibility of Brucella Melitensis Isolates From Sheep in an Area Endemic for Human Brucellosis in Turkey
(Japan Soc vet Sci, 2013) Ilhan, Ziya; Solmaz, Hasan; Ekin, Ismail Hakki
The aim of this study was to assess in vitro antimicrobial susceptibility of Brucella melitensis isolates isolated from naturally infected sheep cases in an area where human brucellosis is endemic, focusing on rifampin (RIF), streptomycin (SM), ciprofioxacin (CPFX), trimethoprim/sulfamethoxazole (TMP/SMZ), gentamicin (GM) and tetracycline (TC) and on 11 other antimicrobials. The identification and typing of Brucella isolates were carried out using standard classification tests and polymerase chain reaction (PCR) methods. Antimicrobial susceptibility testing was carried out on Mueller-Hilton agar. The resistance to SM, CPFX and GM was determined at the rate of 7.3% and to RIF at the rate of 9.7%. The highest (46.3%) resistance was determined against TMP/SMZ. All strains were found to be sensitive to TC at the rate of 100.0%. In conclusion, ovine origin B. melitensis strains evaluated in this study were resistant to at least one antimicrobial (51.2%) that is commonly used in human clinical medicine against brucellosis.
Investigation of Selected Bacterial Agents Causing Sheep Abortion in the Van Province by Rt-Pcr and Histopathological Methods
(veterinarni A Farmaceuticka Univerzita Brno, 2023) Gulaydin, Ozgul; Ozturk, Cihat; Ekin, Ismail Hakki; Ilhan, Ziya; Ilhan, Fatma
Abortion causes significant economic losses in the sheep industry. Determination of the aetiology is important in dealing with abortions. The present study was aimed to identify selected important bacterial pathogens in the abortion cases of sheep. A total of 113 samples (105 aborted sheep foetuses, 4 placentas, and 4 vaginal swab samples) from 85 different sheep flocks were examined by real-time PCR (RT-PCR) regarding Chlamydia (C.) spp., C. abortus, Brucella (B.) spp., B. melitensis, Salmonella (S.) spp., S. Abortusovis, Coxiella (C.) burnetii, Listeria (L.) spp., L. monocytogenes, and Campylobacter spp. All cases that were found to be positive for bacterial agents by RT-PCR, were examined pathologically. Tissue samples of foetuses that were found to be positive for B. melitensis and L. monocytogenes by RT-PCR were also investigated immunohistochemically. A total of 35 (30.9%) samples were found to be positive by RT-PCR, with 15 (42.8%), 9 (25.7%), 5 (14.2%), 4 (11.4%), 1 (2.8%), and 1 (2.8%) of them being identified as C. abortus, B. melitensis, S. Abortusovis, C. burnetii, L. monocytogenes and Campylobacter spp., respectively. The presence of the antigen was confirmed also immunohistochemically in the cases with B. melitensis and L. monocytogenes. As a consequence, C. abortus was found to cause the highest rate of sheep abortion cases, which should be taken into account when implementing control measures in epidemiological investigations.
Isolation of Clostridium Sordellii From Abomasum Lesions of Lambs in Turkey
(Ankara Univ, 2008) Akan, Mehmet; Sareyyupoglu, Bare; Oncel, Taner; Tel, Osman Yasar; Ilhan, Ziya; Cantekin, Zafer
In this study, the isolation of C. sordellii from abomasum lesions of lambs and the confirmation of the isolates by polymerase chain reaction (PCR) was attempted. A total of 298 abomasal specimens (swabs) obtained from lambs of 4 to 8 months of age were investigated. Sampled swabs were inoculated onto blood agar plates and incubated anaerobically. Following the incubation grown colonies were identified according to their morphological and biochemical characteristics. C. sordellii was isolated from 17 of 298 specimens (5.7%). These bacteria were also confirmed to harbour C. sordellii DNA by PCR. In conclusion, the presence of C. sordellii in abomasum lesions was demonstrated in Turkey for the first time with this study.
Köpeklerden Elde Edilen Koagulaz Negatif Stafilokok İzolatlarında Metisilin Direncinin Araştırılması
(2022) Yeşilyurt, Muazzez; Gulaydın, Ozgul; Kaplan, Berivan; Ekın, Ismail Hakki; Ilhan, Ziya; Çelik, Rabia
Koagulaz negatif stafilokoklar, fırsatçı patojen olmalarının yanı sıra köpeklerde çeşitli hastalık olgularından da izole edilmektedir. Metisilin dirençli stafilokoklar diğer β-laktam grubu antibiyotiklere karşı da direnç göstermekte ve bu durum tedavi seçeneklerini kısıtlamaktadır. Bu çalışmada, sağlıklı görünen ve hasta olduğu belirlenen köpeklerden alınan çeşitli örneklerden izole edilen koagulaz negatif Staphylococcus spp. izolatlarında metisilin direncinin belirlenmesi amaçlandı. İzolatlarda metisilin direnci agar dilüsyon yöntemiyle belirlendi. Toplam 429 örnekten konvansiyonel bakteriyolojik yöntemlerle 89 (%20.74) adet koagulaz negatif Staphylococcus spp. izole edildi. İzolatların %19.10’u metisiline dirençli bulundu. Metisilin dirençli izolatların 11 (%64.70)’inde PCR ile mecA geni tespit edildi. Sonuç olarak, bu çalışmada fırsatçı patojenler olarak bilinen koagulaz negatif Staphylococcus spp. izolatlarının köpeklerde neden olabileceği enfeksiyonların tedavisinde metisilin direncine dikkat edilmesi gerektiği kanaatine varıldı.
Occurrence and Antibiotic Susceptibility of Salmonella Serotypes in Apparently Healthy Slaughtered Sheep in Van, Turkey
(Medwell online, 2009) Aksakal, Abdulbaki; Boynukara, Banur; Solmaz, Hasan; Ilhan, Ziya; Kutlu, Ismail; Gulhan, Timur
This study was conducted to investigate the occurrence of Salmonella sp. and to determine their susceptibility to antibiotics in apparently healthy slaughtered sheep. In this research, a total of 600 (300 rectal and 300 vaginal) swabs taken from sheep were used as materials. A total of 9 (1.5%) Salmonella sp. were isolated from samples. Of the 9 Salmonella sp., 6 (2%) were isolated from rectal swabs and 3 (1%) Salmonella serotypes from vaginal swabs. Salmonella strains were serotyped as Salmonella saintpaul. All Salmonella strains were found to be susceptible to ampicillin, enrofloxacin, tetracycline, oxytetracycline, gentamicin, neomycin, chloramphenicol, spectinomycin, cephalothin, amoxycillin/clavulanic acid, trimethoprim+ sulfamethoxazole, nalidixic acid and penicillin G (except 2 isolates) whereas, they were resistant to erythromycin and novobiocin. This is the first time, S. saintpaul was isolated in rectal and vaginal swab samples of the sheep slaughtered in abattoirs in Turkey.
Otitis Eksternalı Köpeklerden İzole Edilen Stafilokokların İn Vitro Antibiyotik Duyarlılıkları
(2022) Ekın, Ismail Hakki; Ilhan, Ziya; Erol, Muharrem; Akyol, Eyüp Tolga; Gulaydın, Ozgul
Multifaktöriyel bir hastalık olan otitisin etiyolojisinde, çeşitli bakteriler de rol oynamaktadır. Hastalığın etkin tedavisinde etiyolojinin bilinmesi ve antimikrobiyal duyarlılık testleri önem arz etmektedir. Bu çalışmada, otitis eksternalı köpeklerden alınan örneklerde stafilokok türlerinin izolasyonu ve izolatların çeşitli antimikrobiyal maddelere in vitro duyarlılıklarının saptanması amaçlandı. Yaşları 3 ay ile 10 yıl arasında değişen, 12 farklı köpek ırkına ait 13’ü (%31.7) dişi, 28’i (%68.3) erkek olmak üzere toplam 41 adet köpekten alınan 82 adet kulak svap örneği materyal olarak kullanıldı. Köpeklerin 30 (%73.17) adetinden bakteriyel bir etken izole edilirken, 11 (%26.83) adet köpeğe ait örneklerde ise üreme olmadı. Kültür pozitif 30 adet köpeğin 24 (%80) adetinden stafilokok cinsine ait bakteriler izole edildi. Bu hayvanların 7 (%29.1) adetinden Staphylococcus aureus, 6 (%25) adetinden S. schleiferi subsp. schleiferi, 5 (%20.8) adetinden koagulaz negatif stafilokoklar (KNS), 4 (%16.6) adetinden S. haemolyticus ve 2 (%8.3) adetinden ise S. epidermidis izole edildi. İzolatların antimikrobiyal duyarlılıkları değerlendirildiğinde, S. aureus suşlarının tamamının sefoperazon/sulbaktam ve sefolatine karşı duyarlı olduğu, S. schleiferi subsp. schleiferi suşlarının ise %83.3’ünün tobramisine dirençli olduğu belirlendi. İzolatlarının %40’ında çoklu antibiyotik dirençliliği belirlenirken, %44’ünde ise metisilin dirençliliği saptandı. Sonuç olarak bu çalışmada, i) S. schleiferi subsp. schleiferi’nin köpeklerdeki otitis eksterna vakalarının primer bakteriyel etkenlerinden biri olabileceği, ii) otitis eksternalı köpeklerin insanlar, hayvanlar ve çevreye gerek çoklu antibiyotik dirençli gerekse metisilin dirençli stafilokok türlerini bulaştırma potansiyeline sahip olabilecekleri düşünüldü.
Phenotypic and Genotypic Characterization of Macrolide-Lincosamide Resistance in Staphylococcus Aureus Isolates From Bovine and Human
(Sciendo, 2023) Gulaydin, Ozgul; Gurturk, Kemal; Ekin, Ismail Hakki; Ilhan, Ziya; Arabaci, Cigdem
In this study, penicillin, oxacillin, and macrolide-lincosamide-streptogramin (MLS) resistance in S. aureus strains that were isolated from bovine mastitis cases, and human patients were investigated. Inducible clindamycin resistance (iML) was not found in 30 bovine isolates, while it was detected in 3 (10%) of 30 human isolates. MIC90 values of penicillin, oxacillin and macrolide-lincosamides (ML) were 2, 0.19, > 256 mu g/ml in bovine isolates and were 3, 3 and 0.19-1.5 mu g/ml in human isolates, respectively. Streptogramin resistance was not found in both bovine and human isolates. Although the mecA gene was detected in all of the oxacillin resistant isolates, blaZ gene could not be detected in penicillin resistant isolates. The erm(B) gene was detected in 5 (38.6%) of 13 ML-resistant bovine isolates, and the mph(C) gene was detected in 2 (66.66%) of 3 human isolates. As a result, resistance to penicillin and oxacillin was found to be higher in human S. aureus isolates, while ML resistance was found to be higher in bovine isolates in this investigation. It was concluded that the presence of genes in extra-chromosomal elements associated to penicillin and macrolide resistance should be investigated. The data obtained from this study will contribute to the studies on antimicrobial susceptibility in the field of human and veterinary medicine.
Studies on Vaccine Development for Ovine Caseous Lymphadenitis
(Ankara Univ Press, 2010) Izgur, Mujgan; Akan, Mehmet; Ilhan, Ziya; Yazicioglu, Nahit
Caseous lymphadenitis (CLA), which is a serious infectious disease of sheep and goats world-wide, has caused significant economic losses in Turkey in recent years. In this study, it was aimed to identify major antigens of Corynebacterium pseudotuberculosis strains isolated in Turkey and to evaluate the efficiency of the vaccine prepared from local strains of C. pseudotuberculosis against bacterial challenge in lambs. C. pseudotuberculosis strains were isolated from six different flocks in Turkey and were classified according to their similarities by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). SDS-PAGE revealed more than 21 bands ranging in size from 15 kDa to 194 kDa present in different concentrations in C. pseudotuberculosis isolates as determined by visual assessment of their approximate molecular masses. Lambs were vaccinated with a bacterin + toxoid + Freund's complete adjuvant (FCA) vaccine, and the vaccine efficiency against bacteriological challenge was evaluated. When a local C. pseudotuberculosis (PI 18) strain was used and formulated as per ml of the vaccine, 1.5x10(8) cfu of C. pseudotuberculosis bacterin + toxoid + 1/2 FCA of the toxoid, we obtained encouraging results regarding the potential of this vaccine to control of CLA in sheep.
Van Bölgesinde Sığır Tüberkülozunun Polimeraz Zincir Reaksiyonu Yöntemi ile Saptanması
(2006) Gülhan, Timur; Solmaz, Hasan; Ilhan, Ziya; Ekin, İsmail Hakkı; Aksakal, Abdülbaki; Boynukara, Banur
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Van Gölü Havzasında Bazı Kanatlı Türlerinde Avian İnfluenza A Virüslerinin Real-time Pcr ile Tespiti, İzalasyonu ve Alt Tiplerinin Belirlenmesi
(2009) Ogün, Erdal; Coven, Fethiye; Ilhan, Ziya; Gülhan, Timur; Ekin, İsmail Hakkı; Aksakal, Abdülbaki; Adızel, Özdemir