Browsing by Author "Ilter, Server"
Now showing 1 - 8 of 8
- Results Per Page
- Sort Options
Article Antioxidant Enzyme Activities, Total Sialic Acid, Vitamin, and Trace Element Status in the Patient With Osteoporosis and Osteopenia(Springer, 2024) Karakus, Yagmur; Ekin, Suat; Ilter, Server; Ediz, Levent; Ekin, Emre CanIn this study, osteoporosis (OS), osteopenia (OP), postmenopausal women with osteoporosis (PMOS) and osteopenia (PMOP), and control participants were evaluated for erythrocyte. CAT, GSH-Px, SOD enzyme activities, MDA, GSH, serum phylloquinone, cholecalciferol, retinol, alpha-tocopherol, TSA, TAS, Co, Mn, Fe, Zn, Cu, Se, Ni, Cd, Pb, Mg, Ca, P, K, Cl levels, and the relations of parameters (F-L-BMD, LT-FT-score) were assessed. In this study, element analyses were carried out using ICP-OES and vitamin determination using the HPLC method. Statistical analyses showed that the OS group had significantly lower FBMD (p < 0.001), LBMD (p < 0.001), GSH (p < 0.01), GSH-Px (p < 0.001), CAT (p < 0.001), alpha-tocopherol (p < 0.05), retinol (p < 0.05), cholecalciferol (p < 0.001), phylloquinone (p < 0.01), Se (p < 0.01), Fe (p < 0.05), Cu (p < 0.05), Co (p < 0.001), Zn (p < 0.001), and Mg (p < 0.01) levels than the control group. However, levels of SOD (p < 0.05) and MDA (p < 0.01) are significantly higher than the control group. It was revealed that there is a significant correlation between Mn-L BMD (r = 0.426; p = 0.024), retinol-L BMD (r = 0.502; p = 0.007), cholecalciferol-L BMD (r = - 0.520; p = 0.005), and with OP; also between retinol-L BMD (r = 0.607; p = 0.008) and with PMOS; also between K-F BMD (r = - 0.504; p = 0.009), Co-LT score (r = - 0.432; p = 0.031) and with PMOP. Our study demonstrates that lower retinol, Co, and Mn and increased OSI and K levels are significantly related to decreased L BMD and F BMD status and oxidative stress in OP, PMOS, and PMOP. A deficiency of Zn, Co, Se, cholecalciferol, and phylloquinone can be a risk factor for the progression of OS, OP, PMOS, and PMOP and could have a negative effect on bone density.Letter Correction: Efficacy of Denosumab in the Treatment of Postmenopausal Osteoporosis: One-Year Follow-Up, Single Center Study(Galenos Publ House, 2023) Tuncekin, Ismail; Ilter, ServerArticle Headache Characteristics in Chronic Neck Pain Patients With Loss of Cervical Lordosis: a Cross- Sectional Study Considering Cervicogenic Headache(int Scientific information, inc, 2023) Delen, Veysel; Ilter, ServerBackground: Loss of cervical lordosis and cervicogenic headache have similar tissue abnormalities, including weakness and atrophy in the neck muscles. Cervicogenic headache is mainly unilateral and is perceived in the occipito-tem-poro-frontal regions. However, it is not clear whether loss of cervical lordosis is a sign of headache with cervi-cal origin. Herein, we aimed to assess and compare headache characteristics in patients with and without loss of cervical lordosis. Material/Methods: This was a cross-sectional study conducted on chronic neck pain patients with (n=38; F/M: 28/10; mean age 33.34 +/- 7.73 yrs; range 18 to 45 yrs) and without loss of cervical lordosis (n=38; F/M: 29/9; mean age 33.13 +/- 6.41 years; range 20 to 45 years), between May 2019 and November 2019. The 2 groups were assessed and com-pared for headache characteristics such as frequency, severity, localization, lateralization, duration, and spread scores. Cervical lordosis was assessed on the lateral cervical radiographs by using posterior tangent technique measuring the C2-C7 total cervical spine angle. Results: The 2 groups were similar for individual features, including age, sex, employment status, and duration of neck pain (P>0.05). The duration of headache attack was longer in patients with loss of cervical lordosis (5.72 +/- 8.12) than in those with normal cervical lordosis (3.29 +/- 3.92) (P=0.009). However, there were no significant differ-ences between the 2 groups for headache characteristics, including frequency, severity, localization, lateraliza-tion, and spread scores (P>0.05). Conclusions: Patients with loss of cervical lordosis have longer duration of headache attack than those without. Loss of cer-vical lordosis may be a specific finding associated with longer cervicogenic headache attacks.Article Hematologic Inflammation Indices for Differentiating Between Brucella, Pyogenic, and Tuberculous Spondylodiscitis(Mdpi, 2024) Baran, Ali Irfan; Binici, Irfan; Arslan, Yusuf; Karaduman, Zekiye Hakseven; Ilter, Server; Tarcan, Tayyar; Unal, MuratInfectious spondylodiscitis is a life-threatening disease and has some challenges in terms of diagnostic, differentiative, and therapeutic processes. Therefore, rapid and effective management of infectious spondylodiscitis is necessary. Hematological inflammation indices (HIIs) such as the neutrophil/lymphocyte ratio and aggregate index of systemic inflammation are derived from blood cells and used as diagnostic, prognostic, predictive, and treatment monitoring indicators. This study aimed to evaluate HIIs for discriminating between infectious spondylodiscitis pathogens. This retrospective comparative study included 116 patients with infectious spondylodiscitis. According to the responsible infectious pathogens, three types of infectious spondylodiscitis were defined: Brucella (n = 51), pyogenic (n = 43), and tuberculous (n = 22). The HIIs were derived from baseline complete blood counts. The three types of infectious spondylodiscitis were statistically compared for the HII scores. We found that the Brucella group had significantly lower HII scores than the pyogenic group (p < 0.05). Also, the Brucella group had significantly lower HII scores than the tuberculous group (p < 0.05). However, no significant differences were found between the pyogenic and tuberculous groups regarding HIIs (p > 0.05). In conclusion, the HIIs may be considered in the differentiation between Brucella spondylodiscitis and other types of infectious spondylodiscitis.Article Isometric Exercise for the Cervical Extensors Can Help Restore Physiological Lordosis and Reduce Neck Pain a Randomized Controlled Trial(Lippincott Williams & Wilkins, 2017) Alpayci, Mahmut; Ilter, ServerObjective The aim of this study was to investigate whether isometric neck extension exercise restores physiological cervical lordosis and reduces pain. Design Sixty-five patients with loss of cervical lordosis were randomly assigned to exercise (27 women, 7 men; mean age, 32.82 8.83 yrs) and control (26 women, 5 men; mean age, 33.48 9.67 yrs) groups. Both groups received nonsteroidal anti-inflammatory drugs for 10 days. The exercise group received additional therapy as a home exercise program, which consisted of isometric neck extension for 3 mos. Neck pain severity and cervical lordosis were measured at baseline and at 3 mos after baseline. Results Compared with baseline levels, cervical lordosis angle was significantly improved in the exercise group (P < 0.001) but not in the control group (P = 0.371) at the end of 3 mos. Moreover, the exercise group was significantly superior to the control group considering the number of patients in whom cervical lordosis angle returned to physiological conditions (85.2% vs. 22.5%; P < 0.001). At the end of 3 mos, pain intensity was significantly reduced in both groups compared with baseline levels (for all, P < 0.001). Nevertheless, considering the change from baseline to month 3, the reduction in pain was about twice in the exercise group compared with the control group (P < 0.001). Conclusions Isometric neck extension exercise improves cervical lordosis and pain.Article Loss of Cervical Lordosis in Chronic Neck Pain Patients With Fibromyalgia: a Cross-Sectional Study(Ios Press, 2023) Delen, Veysel; Ilter, ServerBACKGROUND: Some interrelationships among fibromyalgia (FM), loss of cervical lordosis (LCL), and headache have been reported. Thus, it is sensible to examine LCL as a factor underlying FM and headache. OBJECTIVE: In this study we aimed to assess LCL in chronic neck pain patients (CNPP) with FM and its association with headache features and FM severity. METHODS: CNPP with (n = 55; mean age 40.0 +/- 8.5; range 20 to 55 years) and without FM (n = 55; mean age 38.5 +/- 8.9; range 20 to 55 years) were included in the study. Cervical lordosis was assessed by measuring the Cobb angle on the lateral cervical radiographs. The patients were asked about headache features within the last month. In addition, the CNPP with FM were evaluated by the Turkish version of the Revised Fibromyalgia Impact Questionnaire. RESULTS: There were no statistically significant differences between the groups in terms of age, weight, height, body mass index, working status, and neck pain duration (p > 0.05 for each). The CNPP with FM had significantly reduced cervical lordosis angle compared with those without. The CNPP with FM had significantly higher headache frequency than those without (p = 0.008). There was statistically significant negative correlation between cervical lordosis angle and headache frequency in the CNPP with FM (r: 0.336; p = 0.012). CONCLUSION: According to the results of this study, LCL may be associated with FM and headache frequency in the CNPP with FM.Article Mean Platelet Volume, Red Cell Distribution Width, Platelet-To and Neutrophil-To Ratios in Patients With Ankylosing Spondylitis and Their Relationships With High-Frequency Hearing Thresholds(Springer, 2016) Bozan, Nazim; AlpaycAñ, Mahmut; Aslan, Mehmet; Cankaya, Hakan; Kiroglu, Ahmet Faruk; Turan, Mahfuz; Ilter, ServerThe mean platelet volume (MPV), red cell distribution width (RDW) and neutrophil-to-lymphocyte ratio (NLR) comprise laboratory markers in ankylosing spondylitis (AS). There is a controversy in the literature regarding which type of ear involvement is characteristic of AS. The aim of this study was to simultaneously investigate the MPV, RDW, platelet to lymphocyte (PLR) and NLR in patients with AS and their relationships with high-frequency hearing thresholds. Thirty patients with AS and 35 age-matched healthy subjects were included. Each subject was tested with low- (250, 500, 1000 and 2000 Hz) and high- (4000, 8000, 10,000, 12,000, 14,000 and 16,000 Hz) frequency audiometry. Additionally, the case and control groups were evaluated regarding the average hearing thresholds in bone conduction. The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels were measured. The RDW, MPV, neutrophils, lymphocytes and platelet counts were evaluated with the complete blood count. Furthermore, the NLR and PLR were calculated. The complete blood count, platelet numbers, ESR, CRP and NLR levels were significantly increased in the AS patients compared with the healthy controls (p < 0.001, p = 0.007, p < 0.001, p < 0.001 and p = 0.047, respectively). There was no statistically significant difference in the RDW, PLR or MPV levels (p > 0.05) in the AS patients compared with the healthy controls. The BASDAI score and disease duration were not correlated with the ESR, CRP levels, MPV, PLR, RDW or NLR in patients with AS (all; p > 0.05). The AS patients had increased average measurement values for the hearing threshold in both ears at frequencies of 250, 500, 1000 and 2000 Hz; however, there was no statistically significant difference (p > 0.05). The average values of the hearing threshold in both ears at the high frequencies of 4000, 6000, 8000, 10,000, 12,000 and 14,000 Hz were significantly increased in the case group; however, it was not significantly increased at 16,000 Hz. The current study is the first to investigate the PLR, NLR, MPV and RDW levels in acute AS. We identified a significantly increased NLR, leukocyte count, ESR and CRP in AS patients. Sensorineural hearing loss, especially at extended high frequencies, is common in patients with AS and may represent an extra-articular feature of the disease. The combined use of NLR with the leukocyte count and other clinical assessments may facilitate the diagnostic process of ankylosing spondylitis.Article Short-Term Effects of Kinesio Taping in Women With Pregnancy-Related Low Back Pain: a Randomized Controlled Clinical Trial(int Scientific information, inc, 2016) Kaplan, Seyhmus; Alpayci, Mahmut; Karaman, Erbil; Cetin, Orkun; Ozkan, Yasemin; Ilter, Server; Sahin, Hanim GulerBackground: Pregnancy-related low back pain is a common condition during pregnancy. Kinesio tape is a drug-free elastic therapeutic tape used for treating various musculoskeletal problems. The aim of this study was to investigate the short-term effects of lumbar Kinesio taping on pain intensity and disability in women with pregnancy-related low back pain. Material/Methods: A total of 65 patients with pregnancy-related low back pain were randomly allocated into either Kinesio taping (n=33) or control (n=32) groups. The intervention group was treated with paracetamol plus Kinesio taping, while the control group received only paracetamol. Kinesio taping was applied in the lumbar flexion position, and four I-shaped bands were used. Two bands were attached horizontally, with space correction technique. The remaining 2 bands, 1 on each side of the lumbar spine, were placed vertically, with inhibition technique. Low back pain intensity was measured on a 10-cm visual analogue scale (VAS), and the Roland-Morris Disability Questionnaire (RMDQ) was used for evaluation of disability. Results: Pain intensity and RMDQ scores improved significantly in both groups at 5 days compared with baseline. Considering the degree of treatment effect (the change from baseline to day 5), the Kinesio taping group was significantly superior than the control group in all outcome measures (for all, P<0.001). Conclusions: The results of this study indicate that Kinesio taping can be used as a complementary treatment method to achieve effective control of pregnancy-related low back pain.