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Browsing by Author "Iscan, Akin"

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    Claw Hand Deformity Developing After Mmr Vaccination: the First Case Report
    (Ortadogu Ad Pres & Publ Co, 2012) Karsen, Hasan; Hocanli, Ibrahim; Binici, Irfan; Iscan, Akin; Bayraktar, Mehmet
    Measles, mumps, rubella (MMR) vaccination is included in the routine vaccination program in our country. In the past, many children died or were permanently disabled due to measles and its complications. MMR has significantly decreased with routine and widespread use of MMR vaccination. Many adverse effects such as fever, parotitis, vasculitis, pancreatitis, uveitis, subacute sclerosing panencephalitis, 3rd and 6th nerve paralysis and anaphylaxis may develop following MMR vaccination. 'Claw hand defomity' developing after MMR vaccination has not been reported up to date. Claw hand is the motor dysfunction of the ulnar nerve. This paper presents patients who developed pain, fever and local discharge at the injection area and claw hand deformity after receiving MMR vaccination to the distal part of the deltoid muscle. Claw hand deformity did not improve despite medical and surgical treatment. Thus, we suggest that claw hand deformity may be due to an immunologic reaction. There are some misunderstandings about vaccination in our country. Vaccination rates may decrease if they are not clarified.
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    Visual and Brainstem Auditory Evoked Potentials in Infants With Severe Vitamin B12 Deficiency
    (Tubitak Scientific & Technological Research Council Turkey, 2015) Demir, Nihat; Koc, Ahmet; Abuhandan, Mahmut; Calik, Mustafa; Iscan, Akin
    Background/aim: Vitamin B-12 plays an important role in the development of mental, motor, cognitive, and social functions via its role in DNA synthesis and nerve myelination. Its deficiency in infants might cause neuromotor retardation as well as megaloblastic anemia. The objective of this study was to investigate the effects of infantile vitamin B-12 deficiency on evoked brain potentials and determine whether improvement could be obtained with vitamin B-12 replacement at appropriate dosages. Materials and methods: Thirty patients with vitamin B-12 deficiency and 30 age-matched healthy controls were included in the study. Hematological parameters, visual evoked potentials, and brainstem auditory evoked potentials tests were performed prior to treatment, 1 week after treatment, and 3 months after treatment. Results: Visual evoked potentials (VEPs) and brainstem auditory evoked potentials (BAEPs) were found to be prolonged in 16 (53.3%) and 15 (50%) patients, respectively. Statistically significant improvements in VEP and BAEP examinations were determined 3 months after treatment. Three months after treatment, VEP and BAEP examinations returned to normal in 81.3% and 53.3% of subjects with prolonged VEPs and BAEPs, respectively. Conclusion: These results demonstrate that vitamin B-12 deficiency in infants causes significant impairment in the auditory and visual functioning tests of the brain, such as VEP and BAEP.