Browsing by Author "Kahraman, Ali"

Now showing 1 - 3 of 3

Clinical Profile of Thorax and Lung Injuries Associated With the 2011 Van Earthquake in Turkey
(Modestum Ltd, 2013) Sehitogullari, Abidin; Kahraman, Ali; Sayir, Fuat; Akin, Oral; Sevilgen, Gokcen; Cobanoglu, Ufuk; Aktas, Serdar
The 7.2 and 5.6 magnitude earthquake that struck Turkey on October 23 and November 9, 2011, was one of the deadliest earthquakes in recent decade. Our aim is to determine the clinical profile of crush thoracic traumas resulting from the massive Van earthquake. A retrospective review was undertaken of 39 intervention for chest traumas. Sex distrubition was 21 female and 18 male patients. Thoracic cage, pulmonary parenchyma, and pleura traumas were included in the study. Among the total of 425 hospitalized patients, 39 (9.1%) were thorax and lung injuries. Pneumothorax and rib fractures were the two most frequent pathologies. There were pneumothorax or hemothorax in 31 (79%) patients, bronch ruptures in 2 (5.1%) patients, diaphragmatic ruptures in 2 (5.1%) patients, flail chest in 2 (5.1%) patients and sternal fracture was detected in 2 (5.1%) patients. Totally, 76 ribs fractures were found in 27 (69%) patients, There were 36 (92%) patients with pulmonary parenchymal injuries and 31 (79%) with pleural injuries. Thoracotomy was performed in 4 (10%) patients, while 37 (95%) patients underwent tube thoracostomy. Carinal reconstruction was performed in a patient with bronchus and trachea injuries. Four patients (10%) with severe trauma developed Acute Respiratory Distres Syndrome (ARDS) and two of them died because of developing ARDS. After the patients are admitted to the hospital, we should use an individualized treatment according to the patients recent clinical history and examination. At the same time, traumatic chest injury should be considered in planning the medical response strategies.
A Long-Term Study Assessing the Factors Influencing Survival and Morbidity in the Surgical Management of Bronchiectasis
(Biomed Central Ltd, 2011) Sehitogullari, Abidin; Bilici, Salim; Sayir, Fuat; Cobanoglu, Ufuk; Kahraman, Ali
Background: Although the prevalence of bronchiectasis decreased significantly in developed countries, in less developed and in developing countries, it still represents a significant cause of morbidity and mortality. The aim of this retrospective study is to present our surgical experiences, the morbidity and mortality rates and outcome of surgical treatment for bronchiectasis. Methods: We reviewed the medical records of 129 patients who underwent surgical resection for bronchiectasis between April 2002 and April 2010, at Van Training and Research Hospital, Thoracic Surgery Department. Variables of age, sex, symptoms, etiology, and surgical procedures, mortality, morbidity and the result of surgical therapy were analyzed retrospectively. Results: Mean age was 21.8 year (the eldest was 67 year, the youngest was 4 years-old). Male/female ratio was 1.86 and 75% of all patients were young population under the age of 40. Bilateral involvement was 14.7%, left/right side ratio according to localization was 2.1/1. The most common reason for bronchiectasis was recurrent infection. Surgical indications were as follows: recurrent infection (54%), hemoptysis (35%), empyema (6%), and lung abscess (5%). There was no operative mortality. Complications occurred in 29 patients and the morbidity rate was 22.4%. Complete resection was achieved in 110 (85.2%) patients. Follow-up data were obtained for 123 (95%) of the patients. One patient died during follow-up. The mean follow-up of this patient was 9 months. Mean postoperative hospitalization time was 9.15 +/- 6.25 days. Significantly better results were obtained in patients who had undergone a complete resection. Conclusions: Surgical treatment of bronchiectasis can be performed with acceptable morbidity and mortality at any age. The involved bronchiectatic sites should be resected completely for the optimum control of symptoms.
Serum Paraoxonase-1 Enzyme Activities and Oxidative Stress Levels in Patients With Esophageal Squamous Cell Carcinoma
(Taylor & Francis Ltd, 2014) Sehitogullari, Abidin; Aslan, Mehmet; Sayir, Fuat; Kahraman, Ali; Demir, Halit
Objectives: Oxidative stress is well recognized to play a role in the pathogenesis of many diseases, including cancers. Paraoxonase-1 (PON1) is implicated in the elimination of carcinogenic lipid-soluble radicals produced by lipid peroxidation. Reports on PON1 activities in patients with cancer are conflicting. The aim of this study was to investigate serum antioxidant enzyme activities and oxidative stress levels in patients with esophageal squamous cell carcinoma (ESCC). Patients and methods: Thirty-two patients with ESCC and 33 healthy controls were enrolled. Serum malondialdehyde (MDA) levels and superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), glutathione reductase (GR), paraoxonase, and arylesterase activities were measured spectrophotometrically. Results: Serum paraoxonase, arylesterase, SOD, activities, GSH-Px, and GR activities were significantly lower in patients with ESCC than in controls (all, P < 0.05), whereas serum MDA levels were significantly higher (P < 0.05). Serum MDA levels were significantly correlated with paraoxonase (r = -0.572, P < 0.001) and arylesterase activities (r = -0.597, P < 0.001) in patients with ESCC. Conclusions: This study indicated that ESCC is associated with increased oxidative stress and decreased antioxidant enzyme activities. Decreased serum PON1 enzyme activities may play a role in the progression and/or development of ESCC. Further studies are required to clarify these results.