Browsing by Author "Kalan, Isilay"

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Association of Acromegaly and Multiple Myeloma: a Case Report
(Galenos Yayincilik, 2013) Atmaca, Murat; Yildiz, Saliha; Kalan, Isilay; Ozbay, Mehmet Fatih; Seven, Ismet; Ozturk, Mustafa
Malignancy is an important cause of mortality in acromegaly. Hematological malignancies are very rare in acromegaly. Here, we report an 80-yearold patient with acromegaly and multiple myeloma. Patient died within a month of diagnosis. Previous studies have shown that growth hormone and somatomedin-C activate B lymphocyte and somatomedin-C receptors are found in multiple myeloma cells. Possible effects of growth hormone and somatomedin-C on multiple myeloma progression are discussed in the light of the relevant literature.
Thyrotoxic Hypokalemic Periodic Paralysis: a Case Report
(Galenos Yayincilik, 2012) Atmaca, Murat; Kalan, Isilay; Yildiz, Saliha; Ozbay, Mehmet Fatih; Kacmaz, Murat
Thyrotoxic hypokalemic periodic paralysis is a rare complication of thyrotoxicosis. This clinic condition is often encountered in Asian populations and male gender while thyrotoxicosis is frequently seen in women. The escape of potassium into cell is the mechanism responsible for this disease and its etiology is not completely known. Thyroid hormones, carbohydrate rich diet, alcohol consumption and excessive exercise are regarded as the precipitating factors. This clinical picture is generally difficult to define at first attack. Here, we report a forty-two-year-old male patient with BasedowGraves disease who was diagnosed as having thyrotoxic hypokalemic periodic paralysis during the first paralytic attack. His symptoms improved after potassium replacement and treatment with beta-blocker and antithyroid drugs. The permanent cure was achieved with radioactive iodine ablation therapy.