Browsing by Author "Kalender, Ali Murat"

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An Alternative Method for the Treatment of Osteoid Osteoma
(Professional Medical Publications, 2011) Guner, Savas; Ceylan, M. Fethi; Guner, S. Ilkay; Kalender, Ali Murat; Sahan, Mehmet Hamdi
Osteoid osteoma is a small, self-limiting osteogenic tumor. The success of the treatment depends on complete resection or destruction of the nidus. Open excision or en bloc excision was the classical treatment of osteoid osteoma before the development of minimally invasive percutaneous methods. Computed tomography guidance is required in the operating room in most of the percutaneous procedures. This enables accurate localization of the tumor and tumor excision can be performed with less bone tissue resection. We performed an alternative treatment that enables surgeons working in clinics where this equipment does not exist, to perform easy resection of the tumor through a mini incision. Mini incisional surgery seems to be an efficient and reliable treatment for osteoid osteoma.
Comparison of Anti-Edema Effects of Iloprost and Diclofenac Sodium on Traumatic Rat Paw Edema
(Turkish Assoc Orthopaedics Traumatology, 2010) Uslu, Mustafa; Kilincoglu, Volkan; Toker, Serdar; Kalender, Ali Murat; Dogan, All; Sebik, Ahmet
Objectives: The aim of this study was to compare the anti-edema effects of a stable prostacyclin analogue, iloprost, with parenteral and local forms of a non-steroidal anti-inflammatory drug, diclofenac sodium, on traumatic soft tissue edema. Methods: Thirty-two adult male rats were randomly divided into 4 equal groups. Traumatic edema in one paw of each rat was produced by established protocol. Different drugs were then administered to each group: intraperitoneal (i.p.) saline (group 1, control group), topical diclofenac gel (group 2), i.p. diclofenac sodium (group 3), and i.p. iloprost (group 4). The volume of the paws was measured at baseline (before trauma) and at 1 hour, 2 hours, 4 hours, 8 hours, 24 hours, 48 hours, and 72 hours after trauma. The anti-edema effects of these 3 drugs (diclofenac gel, diclofenac sodium i.p., iloprost i.p.) were compared to each other and to the control group. Results: The greatest increase in paw edema in the first, second and fourth hours was seen in the control and iloprost groups. At the 4-hour measurement, edema levels were all equal except control group. Following 4- and 8-hour measurements, edema began to decrease in all groups. After 8 and 24 hours, the fastest decrease in edema was in iloprost group, with complete resolution of edema by 72 hours. The next fastest decrease in paw volume was seen with i.p. diclofenac sodium, followed by diclofenac gel. Conclusion: Iloprost has experimentally higher anti-edema effect than diclofenac sodium for the conservative treatment of the traumatic soft tissue edema.
The Diagnostic Value of Diffusion-Weighted Magnetic Resonance Imaging in Soft Tissue Abscesses
(Elsevier Ireland Ltd, 2011) Unal, Ozkan; Koparan, Halil Ibrahim; Avcu, Serhat; Kalender, Ali Murat; Kisli, Erol
Purpose: To study the diagnostic value of diffusion-weighted imaging (DWI) in soft tissue abscesses. Materials and methods: Fifty patients were included in this study who were thought to have soft tissue abscess or cystic lesion as a result of clinical and radiological examinations. Localisations of the lesions were: 1 periorbital, 3 breast, 14 intraabdominal, and 32 intramuscular lesions. After other radiological examinations, DWI was performed. The signal intensity values of the lesions were evaluated qualitatively according to the hyperintensity on b-1000 DWI, using 1.5 T MR system. All of the lesions were aspirated after DWI, and detection of pus in the aspiration material was accepted as gold standard for the diagnosis of abscess. Results: In 38 of the 50 patients, hyperintensity was obtained on diffusion-weighted images. False-positive results were maintained in 2 of these patients, and true-positive results were maintained in 36 of them. In 11 of the 50 patients, hypointensity was visualised on diffusion-weighted images. False-negative results were maintained in 3 of these patients, and true-negative results were maintained in 8 of them. An abscess which was seen on post-contrast conventional MRI could not be seen on DWI, and this was regarded as false-negative. Conclusion: The sensitivity and specificity of diffusion-weighted images for detecting soft tissue abscesses were found to be 92% and 80%, respectively. DWI has a high diagnostic value in soft tissue abscesses, and is an important imaging modality that may be used for the differentiation of cysts and abscesses. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
The Effect of Gsm Mobile Phone Electromagnetic Field on Femur Fracture Healing in a Rat Model
(derman Medical Publ, 2012) Kalender, Ali Murat; Goktas, Ugur; Ozbag, Davut; Erturkr, Cemil; Okumus, Mehmet; Guner, Savas; Un, Ahmet
Aim: Biological effects of electromagnetic field (EMF) and their consequences on human health have been the subject of much interest and research in recent years. The aim of this study was to investigate the effects of 900 MHz EMF on femur fracture healing in a rat model. Material and Method: After sixty male Sprague-Dawley rats were exposed to a closed right femur fracture under anesthesia, the reduction and fixation were done with a 21 g needle. Then, 900 MHz radiation (2 W peak output power and 1.04 mW/cm2 power density) was applied to EM group for one hour/day for seven days. The healing was assessed using radiological (Lane and Sandhu classification), histological (Huo scale for callus evaluation), and biomechanical (3-point bending) measures at 2nd, 4th and 6th weeks after fracture. Results: Fracture healing, as assessed radiologically and histopathologically, in Group EM and control animals was similar at 2nd, 4th and 6th weeks. Fracture healing, as assessed biomechanically, was significantly better in Group EM compared to controls in those sacrificed at 2nd week post-procedure (p <0.05). Biomechanical strength was not different between the groups at 4th and 6th weeks. Discussion: 900 MHz EMF from a mobile phone in this rat femur fracture model resulted in no significant difference in healing from controls not exposed to EM radiation.
Effect of Zofenopril on Regeneration of Sciatic Nerve Crush Injury in a Rat Model
(Thieme Medical Publ inc, 2009) Kalender, Ali Murat; Dogan, Ali; Bakan, Vedat; Yildiz, Huseyin; Gokalp, Mehmet Ata; Kalender, Mahmut
Background: Zofenopril is an antioxidant agent which has been shown to have beneficial effects in hypertension and heart failure. The aim of this study was to test the effects of Zofenopril on nerve regeneration and scarring in a rat model of peripheral nerve crush injury. Methods: Twenty-one adult Sprague-Dawley rats underwent a surgical procedure involving right sciatic nerve crush injury. 15 mg/kg Zofenopril was administered orally to seven rats in group Z for seven days. Seven rats in group S received saline orally for seven days. Seven rats in the control group C received no drug after crush injury. Fourteenth and 42nd days after injury, functional and electromyography assessments of nerves were performed. Functional recovery was analyzed using a walking track assessment, and quantified using the sciatic functional index (SFI). After these evaluations, all rats were sacrificed and microscopic evaluations were performed. Results: The Sciatic functional Index (SFI) in group Z on 14th day is different significantly from group S and group C (p = 0.037). But on 42nd day there was no difference between groups (p = 0.278). The statistical analyses of electromyelographic (EMG) studies showed that the latency in group Z is significantly different from group S (p = 0.006) and group C (p = 0.045). But on 42nd day there was no difference between groups like SFI (p = 0.147). The amplitude was evaluated better in group Z than others (p < 0.05). In microscopic evaluation, we observed the highest number of nerve regeneration in the group Z and the lowest in the group C. But it was not significant statistically. Conclusion: Our results demonstrate that Zofenopril promotes the regeneration of peripheral nerve injuries in rat models.
Evaluation of Treatment Results Intertrochanteric Femur Fractures
(2008) Karabulut, Samet; Kalender, Ali Murat
Günümüz yaşlı toplumunda, yaşlılığın beraberinde getirdiği sorunlarla beraber femur trokanter arası kırıkları da Ortopedi ve Travmatoloji biliminin ana meşguliyet sorunlarından bir tanesidir.Trokanter arası femur kırıkları ileri yaşta basit travmalar sonucu oluşmakta, genç ve aktif insanlar yüksek şiddetli travma neticesinde mevcut şikâyet ile sağlık kurumlarına başvurmaktadırlar.Bölgemiz Y.Y.Ü Araştırma ve Uygulama Hastanesi, Ortopedi ve Travmatoloji Kliniğinde 1994?2007 yılları arasında ameliyat olmuş trokanter arası femur kırıklı hastaların geriye dönük olarak dosya ve arşiv bilgileri incelenmiş, son kontrolleri yapılmıştır.Bu çalışmada dosya bilgilerine ulaşılan 128 hastadan 82 hastanın uzun süreli kontrolleri yapılmış, dosya bilgileri incelenen 21 hasta ve 5 yıl içerisinde ölen 25 hasta uzun süreli takip gerektiren istatistiksel bilgiler açısından çalışma dışında tutulmuştur. Hastaların 84'ü erkek, 44'ü kadın hastaydı. 70 hastada sol, 58 hastada sağ taraf kırılmıştı. Hastalar ortalama 47 ay takip edilmişlerdir.Trokanter arası femur kırıklarında güvenilir tespit sağlamak, hastayı erkenden, ağrısız, rahat ve hareketli duruma getirebilmek için cerrahi tedavi gereklidir. 62 hastaya dinamik kalça çivisi, 21 hastaya Ender intramedüller çivi en çok tercih edilen implantlar olmuştur.Hastalar Harris kalça derecesine göre değerlendirilmiş; 82 hastanın muayenelerinde %52,4 mükemmel (43 hasta), %19,5 çok iyi (16 hasta), %6,1 iyi (5 hasta), %17,1 orta (14 hasta) ve %4,9 kötü (4 hasta) sonuç bulunmuştur.Tez çalışmasında elde edilen sonuçların büyük oranda literatür ile uyumlu olduğu görülmüştür.Anahtar sözcükler: İnternal tespit, trokanter arası femur kırığı, osteoporoz, komplikasyon, travma, yaşlılık, erken mobilizasyon.
Hunter's Technique Without Hunter's Rod
(Acta Medica Belgica, 2012) Atik, Bekir; Sarici, Murat; Kalender, Ali Murat; Isik, Daghan; Aydin, Osman Enver
Silicon rods initially advocated by Hunter have been widely used in two-stage flexor tendon reconstruction. Two-stage tendoplasty is an expensive procedure; with the addition of the high cost of rods, it is still more expensive. An experimental study investigated cheaper alternatives to silicon rods, but no clinical studies seem to have been reported so far. This study involved 17 patients undergoing two stage flexor tendon grafting. In all fingers, silicon urinary catheters were used as tendon prosthesis. The Wehbe et al modification of the Boyes and Stark classification was used for preoperative classification and Strickland formulation and Buck-Gramcko criteria for postoperative analysis. This clinical study showed that comparable clinical results and proper pseudosheaths for tendon grafting with similar histological and physical features can be obtained using a silicon urinary catheter which is fifty times less costly than Hunter's rod.
Mini-Open Technique for the Achilles Tenotomy in Correction of Idiopathic Clubfoot - a Report of 25 Cases
(Amer Podiatric Med Assoc, 2008) Dogan, Ali; Kalender, Ali Murat; Seramet, Ebubekir; Uslu, Mustafa; Sebik, Ahmet
Achilles tenotomy is performed for the residual equinus deformity in the Ponseti method of clubfoot treatment. In the present article, we describe a mini-open Achilles tenotomy technique to prevent complications that could occur during tenotomy. This technique was performed on 15 patients (25 feet) during a 3-year period in our clinic on patients whose equinus deformities could not have been corrected by manipulations. Clear improvement (mean angle, 30) was observed in equinus in our patients, and we have not seen any complication in this method. We conclude that direct visualizing of the tendon with mini-open incision may reduce the risk of neurovascular injury, especially for surgeons who are not experienced.
Mitchell's Osteotomy With Mini-Plate and Screw Fixation for Hallux Valgus
(Sage Publications inc, 2013) Kalender, Ali Murat; Uslu, Mustafa; Bakan, Betul; Ozkan, Fuat; Erturk, Cemil; Altay, Mehmet Akif; Kalender, Mahmut
Background: The aim of this study was to evaluate the use of mini-plate and screw fixation to stabilize the first metatarsal osteotomy in patients undergoing Mitchell bunionectomy, with the outcomes of interest being radiological alignment and the time to bony union. Methods: We used mini-plates and screws in 43 feet of 25 patients to avoid cast immobilization and prevent osteotomy displacement. The mean age at operation was 45.4 +/- 13.4 years (range, 17.0-65.0 years). The mean follow-up was 16.9 +/- 3.6 months (range, 12.0-30.0 months). The hallux valgus angles, intermetatarsal angles, and American Orthopaedic Foot and Ankle Society (AOFAS) forefoot scores were evaluated preoperatively and at postoperative month 12. Results: The mean preoperative value for the hallux valgus angle was 35.9 +/- 4.4 degrees (range, 26.0-45.0 degrees) and for the intermetatarsal angle was 12.1 +/- 1.4 degrees (range, 10.0-15.0 degrees). The mean postoperative value for the hallux valgus angle was 16.0 +/- 2.12 degrees (range, 12.0-20.0 degrees) and for the intermetatarsal angle was 7.7 +/- 1.2 degrees (range, 5.0-10.0 degrees). The mean AOFAS score was 50.5 +/- 12.8 points (range, 30.1-76.0 points) preoperatively and 75.9 +/- 11.3 points (range, 43.3-92.3 points) at postoperative month 12. Improvement of range of motion of the metatarsophalangeal joint, pain relief, and satisfactory alignment of the first ray were achieved in 41 feet (95.3%). Conclusions: We recommend this fixation for Mitchell's bunionectomy because it provided stable fixation without the need for casting.
Review of Van Earthquakes Form an Orthopaedic Perspective: a Multicentre Retrospective Study
(Springer, 2013) Guner, Savas; Guner, Sukriye Ilkay; Isik, Yasemin; Gormeli, Gokay; Kalender, Ali Murat; Turktas, Ugur; Dursun, Recep
This is a descriptive analysis, of victims of Turkey's October 23, 2011 and November 21, 2011 Van earthquakes. The goal of this study is investigated the injury profile of the both earthquakes in relation to musculoskeletal trauma. We retrospectively reviewed medical records of 3,965 patients admitted to in seven hospitals. A large share of these injuries were soft tissue injuries, followed by fractures, crush injuries, crush syndromes, nerve injuries, vascular injuries, compartment syndrome and joint dislocations. A total of 73 crush injuries were diagnosed and 31 of them were developed compartment syndrome. The patients with closed undisplaced fractures were treated with casting braces. For closed unstable fractures with good skin and soft-tissue conditions, open reduction and internal fixation was performed. All patients with open fracture had an external fixator applied after adequate debridement. Thirty one of 40 patients with compartment syndrome were treated by fasciotomy. For twelve of them, amputation was necessary. The most common procedure performed was debridement, followed by open reduction and internal fixation and closed reduction-casting, respectively. The results of this study may provide the basis for future development of strategy to optimise attempts at rescue and plan treatment of survivors with musculoskeletal injuries after earthquakes.
Ring Leg Deformity in Bartsocas-Pappas Syndrome
(Elsevier Science Bv, 2009) Kalender, Ali Murat; Dogan, Ali; Sebik, Ahmet; Gokalp, M. Ata
Introduction: We reported an extremely rare foot deformity in Bartsocas-Pappas syndrome. This patient family is from Van that is a city in the east part of Turkey and the family is Turkish origin. In literature review we find only two cases resembling to this deformity. Case presentation: A 20-day-old infant with an extremely rare type lower extremity anomaly. There was a skin band between the syndactylia 2nd and 3rd toes of the right and left feet. Conclusion: This deformity resembles to a ring. We could not find a specific name for this anomaly. Therefore we want to advise a name "ring leg" deformity to describe this deformity. (C) 2009 Elsevier Masson SAS. All rights reserved.