Browsing by Author "Kamaci, M."
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Article Association of Maternal Obesity and Fetal Gender With Preeclampsia(2003) Üstün, Y.; Engin Üstün, Y.; Zeteroǧlu, Ş.; Şahin, G.; Kamaci, M.OBJECTIVE: To evaluate the role of maternal obesity and fetal gender in the pathoge-nesis of preeclampsia and to determine the fetal gender ratio and difference of body mass index in normal and preeclamptic group. STUDY DESIGN: In a prospective study design, in one year period, one of every 10 normal pregnancies (n=59) and all preeclamptic pregnancies were enrolled into the study (n=42). Clinical characteristics recorded included maternal age, body mass index, gravidity, parity, estimated gestational age, mode of delivery, neonatal birth weight, and fetal gender. RESULT(s): There were no statistically significant differences in maternal age, gravidity and parity between the groups. Body mass index was significantly higher in preeclamptic group (p=0.001) but no difference was found in fetal gender between the groups. CONCLUSION(s): Maternal obesity has a probable role in the pathophysiology of preeclampsia but fetal gender seems to play no role.Article A Case of Parasitic Myoma Diagnosed by Immunohistochemistry(2004) Kamaci, M.; Özen, S.; Zeteroǧlu, Ş.; Oral, H.; Şengül, M.; Kolusari, A.A case of parasitic myoma diagnosed by immunohistochemistry is presented. The importance of histopathological and immumohistochemical procedures in the differential diagnosis of parasitic myoma from stromal tumors was discussed.Article A Case Report of Patient With Uterine Torsion and Glob Vesicale Mimicking Twin Pregnancy(2012) Kamaci, M.; Aksin, Ş.; Kolusari, A.; Kurdoǧlu, M.; Coşkun Erol, Ü.; Adali, E.The patient who was 35-year-old, gravidity 8, parity 7 and who had followed for a long time by the active phase of labor was referred to our clinic urgently due to cephalopelvic disproportion and fetal shoulder dystocia by helicopter ambulance. After the ultrasonographic examination, a fetus with bradicardia and whose measurement was 38th gestational week was noted and patient was taken up for emergency cesarean section. Intraoperatively, glob vesicale and uterine torsion were noted. The patient might be evaluated as a twin pregnant woman due to the pressure to urethra and bladder neck by fetal head with a severe uterine contraction and torsion of the pregnant uterus. We aimed to present the management of the patient with glob vesicale and torsion of the pregnant uterus on the light of the literature. Copyright © 2012 by Türkiye Klinikleri.Article Delivery Methods, Perinatal Mortality and Obstetric Complications in Multiple Pregnancies(2004) Kamaci, M.; Zeteroǧlu, Ş.; Şahin, H.G.; Şengül, M.; Gülümser, S.; Bolluk, G.OBJECTIVE: To evaluate the outcome of multiple pregnancies, which were in the high- risk pregnancy groups and to investigate the factors playing role at perinatal mortality. STUDY DESIGN: Ninety-six cases with multiple pregnancies delivered at Gynecology and Obstetrics Clinic of Research and Training Hospital of The Medical Faculty of Yüzüncü Yil University between January 1997-January 2004 were included in this study. Ninety-four twin pregnancies and 2 triplet pregnancies were reviewed retrospectively and then mortality rates, congenital anomalies, complications and delivery characteristics of these cases were analyzed. The statistical analysis was performed by SPPS (The Statistical Computer Software, version 9.05, Chicago, Illinois). RESULT(s): The incidence was 1.66% (94/5,632) for twin pregnancies; and 0.035% (2/5,632) for triplet pregnancies. The antenatal follow-up rate for the pregnant women during this study was 26.36%. The mean age of pregnant women was 28.3±5.65 and mean gestational age was 35.18±5.35 weeks. Fifty-three of these cases (55.2%) were delivered vaginally, while 42 cases (43.75%) were delivered by cesarean section. In one case, first fetus was delivered vaginally and the second fetus by cesarean section. Apgar scores (1-5 minutes) in 16 newborns were 0-0, in 56 newborns were below 7 and in 124 newborns were above 7. Birth weights were below 1000 gr. in 30 (15.5%) newborns, were between 1000 and 2499 gr. in 88 newborns (45.4%), and were above 2500 gr. in 76 newborns. Perinatal and neonatal mortality was highest among the babies with birth weights below 1500 gr. and gestational age under 27 weeks. Perinatal mortality rate was found to be 0.82% and neonatal mortality rate to be 0.98% among multiple pregnancies. CONCLUSION(s): The frequency of multiple pregnancies was consistent but the perinatal mortality rate was higher than the literature. Immaturity and prematurity were determined as the important factors increasing perinatal mortality.Article Eclampsia With Neurological Complications: a Five-Year Experience of a Tertiary Centre(I R O G Canada, inc, 2013) Kurdoglu, Z.; Ay, G.; Sayin, R.; Kurdoglu, M.; Kamaci, M.Purpose: The neurological signs and symptoms in 107 pregnant women with eclampsia in the last five years at the Department of Obstetrics and Gynecology at the Yuzuncu Yil University School of Medicine are presented. Materials and Methods: The medical records of 107 pregnant women with eclampsia in the Clinic of Obstetrics and Gynecology at the Yuzuncu Yil University consulted with neurology clinic from September 2005 to December 2010, were evaluated. Results: The most common symptoms of the patients were seizure, headache, and seeing spots of light. Although neurologic examination was normal in 81 patients, 26 had pathological signs. The most common neurologic pathologic signs determined were alterations in consciousness. Conclusion: In eclamptic patients, brain scanning might reveal pathological results in spite of normal neurological examination. With neurological examination and brain scanning, it may be possible to diagnose and treat severe complications that may otherwise result in maternal mortality.Article Eight Years' Experience of Uterine Rupture Cases(2005) Zeteroglu, S.; Ustun, Y.; Engin-Ustun, Y.; Sahin, H.G.; Kamaci, M.Ruptured uterus is a serious obstetric emergency with a high maternal and perinatal mortality. It is a preventable and common obstetric problem in developing countries. The objective of this study was to review the incidence, methods of diagnosis and maternal and perinatal morbidity and mortality associated with uterine rupture. Case notes were reviewed for all patients with a ruptured uterus at Yüzüncü Y1l University Medical Faculty Department of Obstetrics and Gynaecology from January 1995 to August 2003. Relevant data relating to the clinical characteristics of labour, operative procedures, maternal and perinatal outcome were assessed. There were 20 cases of ruptured uteri. The incidence was 0.40%. When patients referred from other hospitals were excluded, the revised ratio was 0.12%. There were 13 (65%) complete and seven (35%) incomplete ruptures. Nine (45%) cases occurred in patients with scarred uteri. Ten (50%) cases were grand multiparous. Subtotal abdominal hysterectomy was performed in five (25%) cases, total abdominal hysterectomy was performed in two (10%) cases and the remaining 13 (65%) cases had uterine rupture repair. There were two (10%) maternal deaths. Both of them were referred from other hospitals. There were seven (35%) perinatal deaths attributable to uterine rupture. Occurrence of uterine rupture is significantly associated with grand multiparity, scarred uterus, lack of antenatal care, unsupervised labour at home and low socioeconomic status of the patients. These factors are largely preventable. © 2005 Taylor & Francis.Article Giant Bladder Leiomyoma Presenting as a Pelvic Mass: a Case Report(I R O G Canada, inc, 2007) Erdemoglu, E.; Kamaci, M.We present a rare case of bladder leiomyoma with an unusual presentation as a pelvic mass. Bladder leiomyomas are very rare tumors, compromising less than 0.43% of all bladder tumors. Magnetic resonance imaging showed a 16 x 13 cm mass covering the entire pelvis and extending up to the umbilicus. There was a 20 x 20 x I I cm immobile mass originating from the bladder at laparotomy. The mass was removed by bladder-sparing surgery and was reported to be leiomyoma. We conclude that bladder leiomyomas should be preoperatively recognized as a cause of pelvic mass in order to make the possible diagnosis.Article Hypopharyngeal Cancer in Pregnancy: Case Report(Ortadog u Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S., 2015) Kamaci, M.; Şahin, H.G.; Kolusari, A.; Adali, E.; Kurdoʇlu, Z.; Kurdoʇlu, M.; Adali, F.Hypopharyngeal cancer is very rarely seen in pregnancy. The patients may apply with the symptoms and signs of difficulty in swallowing, sore throat or hemoptysis. A thirty nine years old G:5, P:3, A:2 pregnant woman whose fetal biometric measures were consisted with 32 weeks of gestation applied with difficulty in swallowing and sore throat. On the magnetic resonance imaging, a vegetative mass with 6.5x3.5x3.5 cm dimensions was detected at the hypopharyngeal location and the biopsy was reported as "well differentiated squamous cell carcinoma". The patient was regarded as stage IV (T4N1M0) inoperable by the Department of Otolaryngology. The patient whose chemoradiotherapy was delayed to the postpartum period upon the desire of the family was delivered at 37th gestational week by cesarean section under spinal anesthesia. It was learned that the patient was given a chemoradiotherapy in another center, 2 weeks after the delivery. In this case presentation, the management of a pregnant woman with hypopharengeal cancer which is a very rare condition in pregnancy is presented. Copyright © 2015 by Türkiye Klinikleri.Article Ovarian Stimulation in Obese and Non-Obese Polycystic Ovary Syndrome Using a Low-Dose Step-Up Regimen With Two Different Starting Doses of Recombinant Follicle-Stimulating Hormone(Sage Publications Ltd, 2008) Yildizhan, R.; Adali, E.; Kolusari, A.; Kurdoglu, M.; Yildizhan, B.; Sahin, H. G.; Kamaci, M.Sixty-seven infertile women with polycystic ovary syndrome (PCOS) were divided into two groups, obese and non-obese, according to their body mass index. Waist-to-hip ratio, insulin resistance, total testosterone and dehydroepiandrosterone sulphate levels were significantly elevated in obese, compared with non-obese, patients. Both groups were treated with a low-dose step-up protocol of recombinant follicle-stimulating hormone (rFSH) with a starting dose of 50 IU/day and, every third day, a 25-IU increase in the dose until the appropriate dose was achieved for each individual, up to a maximum of 175 IU/day. In the obese group only, repeat therapy commenced in the second ovulatory cycle in women who had not become pregnant, however a starting dose of 75 IU/day was then used, with incremental and maximum dose as before. The results of the starting dose of 75 IU/day rFSH were compared with the results of a 50 IU/day rFSH starting dose in the obese group. A starting dose of 50 IU/day rFSH in a low-dose step-up regimen was found to be effective, safe and well-tolerated for inducing follicular development in non-obese infertile women with PCOS. However, for obese PCOS patients, a starting dose of 75 IU/day rFSH is recommended.Article Placental Pathologic Features in Preeclampsia and Normal Pregnancies(2005) Engin Üstün, Y.; Üstün, Y.; Zeteroǧlu, Ş.; Güvercinci, M.; Kamaci, M.; Uǧraş, S.AIM: The objective was to evaluate placental pathologic features in normal and preeclamptic pregnancies. STUDY DESING: Eighty-three preeclamptic-eclamptic and 30 control pregnant women without systemic disease between October 2001 and September 2002 were prospectively recruited. Placental pathologies were evaluated due to macroscopic findings and nine histological parameters on light microscope. Statistics included student t test and chi-square test. RESULT(s): Increased syncytiotrophoblast knotting, cytotrophoblast proliferation, focal perivillous fibrin deposition, villous stromal fibrosis, fibrinoid necrosis, maturation, basal membrane thickening, mineralization in basal membrane and villous stromal edema were more common in the study group compared to the control group. Fibrinoid necrosis in uteroplacental vessels, villous stromal fibrosis, mineralization in basal membrane and villous stromal edema were not seen in any patient in the control group. CONCLUSION: Placental pathologic features play an important role in the pathophysiology of preeclampsia.Article Prenatal Diagnosis of Urethropelvic Obstruction and Assesment of Fetal Renal Function: Case Report(2006) Erdemoglu, E.; Kolusari, A.; Şahin, H.G.; Kamaci, M.Fetal obstructive renal anomalies ar the most common urinary anomaly. Obstuction is particularly is encountered in ureteropelvic junction, vesicoureteral juction or urethra. Accurate localisation of obstruction and status of fetal kidneys are of utmost importance in prognosis and intrauterin management. Thirtythree years old, G6P5A0 women at 20th gestational weeks was refered for anhidroamnios and urinary to deparment of Obstetrics and Gynecology, Yuzüncü Yil Univeristy Medical Faculty. B-mod ultrasonographic examination was likely a posterior urethral valve however, color doppler and pulse doppler examination revealed obstruction cranial to fetal bladder. Pyelourethrocenetsis to evaluate renal function and amnioinfusion was performed. Right renal cortex was thin and hiperechogenic, collecting tubules were dilated. Collecting tubules of right kidney was minimally dilated. Biochemical analysis of aspirated fluid and anhidroamniosis gave irreversible renal damage and pregnancy was terminated. There was left renal duplication and right grade 4 hydronephrosis due to ureteopelvic obstruction. Bladder and urethra was normal. Color doppler and pulse doppler examiation should be incorporated to B-mod examination to assess localisation of urinary obstruction. Uretherocentesis and amniotic fluid index should be examined in order to evaluate prognosis of fetal kidneys.Article Primary Giant Leiomyoma of the Ovary -: Case Report(I R O G Canada, inc, 2006) Erdemoglu, E.; Kamaci, M.; Bayram, I.; Guler, A.; Guler Sahin, H.Primary leiomyoma of the ovary, which is of unknown origin, is an extremely rare tumor of ovary. We report a rare case of giant primary ovarian leiomyoma with an unusual presentation, ascites, elevated CA125 and discuss the preoperative imaging findings. A 45-year-old woman was referred for evaluation of an adnexal mass of 8 x 9 cm with ascites and elevated CA125 levels. Preoperative imaging studies were in accordance with fibroma/thecoma. At laparotomy total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed. Histological and immunhistochemical examination revealed primary ovarian leiomyoma.Article Rectal Cancer and Pregnancy: Report of Two Cases(I R O G Canada, inc, 2009) Kolusari, A.; Ugurluer, G.; Kotan, C.; Sahin, H. G.; Kamaci, M.Colorectal cancers are rare during pregnancy and the management is controversial and challenging. Prognosis is usually unfavorable due to late diagnosis since the presenting symptoms of colorectal cancer are attributable to the usual manifestations of pregnancy. Management depends on the patient's age and desire for future pregnancy, gestational age, cancer stage and religious principles. Thus, the treatment should be individualized. We present two cases of rectal cancer during pregnancy.Article The Relationship Between Clinico-Biochemical Characteristics and Psychiatric Distress in Young Women With Polycystic Ovary Syndrome(Sage Publications Ltd, 2008) Adali, E.; Yildizhan, R.; Kurdoglu, M.; Kolusari, A.; Edirne, T.; Sahin, H. G.; Kamaci, M.The relationship between clinico-biochemical characteristics and self-reported psychological parameters in 42 women with polycystic ovary syndrome (PCOS) and 42 age-matched healthy controls was examined. The General Health Questionnaire was used (GHQ-12) to ascertain emotional distress and the Beck Depression Inventory (BDI) to determine depressive symptoms. Emotional distress, depressive symptoms, hirsutism score, body mass index (BMI), waist-to-hip ratio (WHR), luteinizing hormone/follicle-stimulating hormone ratio, serum total testosterone, dehydroepiandrosterone sulphate levels and the insulin resistance index were significantly greater in women with PCOS than in healthy women. The BDI and GHQ-12 scores of the women with PCOS were significantly higher than those of the control group (BDI, 11.69 +/- 9.49 vs 5.80 +/- 4.58; GHQ-12, 3.38 +/- 3.38 vs 1.54 +/- 1.97, respectively), and BMI and WHR were positively correlated with the BDI and GHQ-12 scores. Clinicians should be aware of the increased risk of emotional distress and depression in women with PCOS, especially those who are obese, and of the need to screen these patients for such symptoms.Conference Object Serum Advanced Oxidation Protein Products, Myeloperoxidase and Ascorbic Acid in Pre-Eclampsia(Blackwell Publishing, 2006) Noyan, T.; Guler, A.; Sekeroglu, M.; Kamaci, M.Article Should We Use Urinary Catheter Routinely at Cesarean Delivery(2007) Kolusari, A.; Zeteroǧlu, Ş.; Şahin, H.G.; Ramazan, S.; Kamaci, M.OBJECTIVE: The aim of the study was to compare intraoperative complications and postoperative morbidity of patients to whom urinary catheter were performed or not in cesarean deliveries. STUDY DESING: This study was designed as a prospective randomised study. Fifty patients (Group 1) who delivered with cesarean section after spontaneous mixture were compared with fifty patients (Group 2) to whom Foley urinary catheter were performed before the opertaion for intraoperative complications and postoperative morbidity. FINDINGS: There were no significant differences between the groups for age, gravity, parity, cesarean indications, factors those could increase postoperative infectious risks and operative time. No intraoperative complications were noticed in both groups. Postoperative mobilization was significantly earlier in Group 1 (6.58±1.69 hours vs 12.52±4.48 hours). The average time to first void was 5.24±3.53 hours in Group 1. In Group 2, two patients (% 4) who had glob vesicate required urinary catheter drainage (Both of them had epidural anesthesia). Urinary catheter was removed at 12.08±4.42 hours in Group 2 patients. There were no urinary tract infections in group 1, four in group 2 patients which reached statistical significance. CONCLUSION: Use of urinary catheter at cesarean delivery increases postoperative urinary tract infections. We think that use of urinary catheter at cesarean delivery is ineffective.