Browsing by Author "Kara, Tolga"

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Investigation of Changes in Oxidative Stress Before and After Nasal Packing Following Nasal Septoplasty
(Ortadogu Ad Pres & Publ Co, 2008) Noyan, Tevfik; Kiroglu, A. Faruk; Kara, Tolga; Keskin, Siddik
Objective: The aim of the study was to investigate the changes of the oxidant and antioxidant system in blood samples before and after nasal packing following nasal septoplasty. Material and Methods: A total of 23 patients, 7 females and 16 males, who were planned to undergo nasal septoplasty were included in the study. Nasal packing was removed at postoperative 48 hours in all patients. Blood gases, serum advanced oxidation protein products (AOPP), serum and erythrocyte malondialdehyde (MDA) levels, and catalase (CAT) activity were measured at preoperative 24 hours (period 1), postoperative 24 hours (period 2) and on postoperative day 15 (period 3) in all subjects. Results: pO2, pCO2, 02 saturation and HCO3 values were similar at all three periods. MDA level was lower and CAT activity in erythrocyte was higher at period 3 compared to periods 1 and 2. Serum CAT activity was also increased at period 3 compared to period 1. Serum MDA and AOPP levels did not change among the periods. Conclusion: The findings suggest that a decrease in oxidative stress as indicated. by the decrease in lipid peroxidation and increased CAT activity may have a protective role via free radical-scavenging properties 15 days after the operation.
Isolated Turbinitis and Pneumatization of the Concha Inferior in a Child
(W B Saunders Co-elsevier inc, 2007) Kiroglu, A. Faruk; Cankaya, Hakan; Yuca, Koksal; Kara, Tolga; Kiris, Muzaffer
Concha bullosa of the inferior turbinate is an extremely rare anatomic malformation with 11 reports of this condition in the literature. The inferior turbinate is an independent bone originating from the lateral nasal wall. Although inferior concha bullosa is generally asymptomatic and diagnosed incidentally by computed tomography, nasal obstruction, headache, and epiphora are some of the possible symptoms. Isolated turbinitis with no additional paranasal infection is also very rare. Although there is only 1 reported case of pediatric inferior concha bullosa before, this case is the first pneumatized inferior concha with associated isolated turbinitis. (C) 2007 Elsevier Inc. All rights reserved.
Prevalence and Risk Factors of Otitis Media With Effusion in School Children in Eastern Anatolia
(Elsevier Ireland Ltd, 2012) Kiris, Muzaffer; Muderris, Togay; Kara, Tolga; Bercin, Sami; Cankaya, Hakan; Sevil, Ergun
Objective: To investigate the prevalence and demographic, environmental and child associated risk factors of OME in schoolchildren in Eastern Anatolia, Turkey, and analyze the results with reference to the review of the literature. Methods: A total of 2355 children who were attending two different primary schools, one located in low, and the other located in a high socioeconomic district of city of Van were screened and 2320 children who met the inclusion criteria were enrolled to study. Standardized questionnaires that include nine questions for determination of risk factors were delivered to the parents to be filled before examination of each child. All of the children underwent both otoscopic examination and tympanometric evaluation to provide high accuracy on the diagnosis of OME. The association between children diagnosed as OME and the answers to the questionnaires were evaluated. Also, teachers of the children were asked to complete a questionnaire evaluating child's level of school success, and the success levels of children with or without OME were compared. Results: The prevalence of OME was found to be 10.43%. Second-hand smoking (p < 0.0001), low socioeconomic status (p < 0.001), living in a crowded house (p < 0.001), presence of atopy (p < 0.01), lack of breast-feeding (p < 0.05), presence of URTI (p < 0.0001), young age (p < 0.001) and snoring (p < 0.0001) were found to be associated with prevalence of OME. No significance was found for duration of breast-feeding, gender, birth history and previous otolaryngological operations. Also, children with OME were tended to be less successful in terms of school success. Conclusions: The potential of OME to cause serious sequelae and complications that may affect children's life long-term, makes the disease an important health problem. Environmental, epidemiologic and familial factors play an important role in pathogenesis of OME. Caretakers must be informed about these highly modifiable risk factors, by this way the development or delayed diagnosis of the disease that may cause serious consequences can be prevented. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
The Prevalance and Risk Factors for the Secretory Otitis Media (SOM) in the School of the City Centre of Van
(2008) Kara, Tolga; Kırış, Muzaffer
Çocukluk çağının sık görülen hastalıklarından biri olan SOM tanı güçlüğü nedeniyle gözden kaçabilmekte ve KOM gelişmesi yanında kalıcı sekellere de neden olmaktadır. Ayrıca SOM'nın çocuklarda dil gelişimi ve öğrenme üzerine de olumsuz etkileri vardır. Bu nedenle hastalığın tanınması yanında sebep olan etyoloji ve risk faktörlerinin belirlenmesi, hastalığın önlenmesi ve tedavisi açısından oldukça önemlidir.SOM oluşumunda birçok etiyolojik ve risk faktörleri mevcuttur. Mevsim, ÜSYE, alerji, kalabalık aile ve okul ortamı, sigara dumanı, sosyoekonomik düzey ve anne sütü bu faktörlerden önemli olanlar içindedir.Çalışmamızda Van il merkezinde iki okulda yaşları 6-11 arasında değişen 2320 çocukta SOM ve KOM prevalansını, SOM sekel ve komplikasyonlarını ile risk faktörlerini belirlemeyi amaçladık.Çalışmamızda 2320 çocuktan 242'sinde (%10.41) SOM tespit edildi. Bu oran ülkemiz ve Avrupa üzerindeki SOM prevalansları ile uyumlu bulunmuştur. Erkek ve kız çocukları arasında SOM prevalansı açısından anlamlı bir fark bulunmamıştır.Sosyoekonomik seviyesi yüksek olan okulda 103 (%8.56) çocukta SOM mevcutken, öğrencilerinin sosyoekonomik seviyesi düşük olan okulda 139 (12.44) çocukta SOM tespit edilmiştir. Sosyoekonomik seviyesi düşük olan okulda SOM prevalansı anlamlı düzeyde yüksek bulunmuştur.SOM ile ÜSYE, alerjik rinit ve pasif sigara içimi birlikteliği anlamlı oranda yüksek bulunmuştur. Anne sütü alım süresi ile SOM arasında anlamlı bir birliktelik bulunmamıştır.SOM veya KOM mevcut olan olguların ders başarı durumları ile kontrol grubundaki kulak patolojisi olmayan olguların ders başarı durumları karşılaştırıldı. SOM veya KOM'nın ders başarı durumunu istatistiksel olarak kötü yönde etkilediğini saptadık.SOM komplikasyonlarından biri olan KOM'nın sosyoekonomik seviyesi düşük olan okulda anlamlı olarak daha sık bulunmuştur. Bunun sebebi olarak klinik takip ve tedavideki eksikliğe ve ailenin hastalığın farkında olmamasına bağlanılmıştır.Anahtar Kelimeler: Sekretuar otitis media, kronik otitis media, prevalans, risk faktörleri