Browsing by Author "Karadag, R."

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A Co-Occurrence of Familial Isolated Cherry Red Spot and Multiple Lens Opacities
(Nature Publishing Group, 2014) Esmer, O.; Karadag, R.; Soylu, E.; Dogan, M.
Purpose To present a co-occurrence of familial isolated cherry red spot (CRS) and multiple lens opacities in all siblings from the same family without any other systemic or ocular diseases. Methods Four siblings from the same family had bilateral punctate lens opacities and bilateral CRS at the macula. Results The oldest one had left eye exotropia and amblyopia, otherwise the other siblings had no additional ocular findings. Systemic investigation, physical examination, and laboratory tests were within normal limits. Conclusion Bilateral isolated CRS along with punctate lens opacities were seen in all siblings from the same family without any systemic and ocular diseases.
Fixed Drug Eruption Induced by Topical Olopatadine Ophthalmic Solution
(Sage Publications Ltd, 2012) Bilgili, S. G.; Karadag, A. S.; Karadag, R.; Bulut, G.; Calka, O.
Fixed drug eruption (FDE) usually develops after oral administration and is described as a cutaneous reaction recurring at the same location each time the drug is taken. Olopatadine is both a H I histamine receptor antagonist and a mast cell stabilizer, indicated for the treatment of allergic conjunctivitis. Here, we report a 14-year-old male patient who developed FDE localised on the lateral side of periorbital rim bilaterally, whilst applying olopatadine 0.1% ophthalmic solution for the treatment of allergic conjunctivitis. As far as we know, FDE due to olopatadine has not been previously reported in the literature. We deem it appropriate to report this case because FDE that results from the application of topical drugs is a rare event in the literature.
Gapo Syndrome Associated With Pyoderma Vegetans: an Unreported Co-Existence
(Medecine Et Hygiene, 2013) Karadag, A. S.; Calka, O.; Bilgil, S. G.; Karadag, R.; Bulut, G.
GAPO syndrome associated with pyoderma vegetans: an unreported co-existence: GAPO syndrome is a rare autosomal recessive disease and an acronym composed of growth retardation, alopecia, pseudoanodontia, optic atrophy. Approximately 38 cases have been reported in literature until now. Pyoderma vegetans is a chronic inflammatory disease characterized with vesicopustular, exudative and vegetative lesions usually localized on face, scalp, axilla and genitalia. Pyoderma vegetans is attributed to a bacterial infection frequently occurring in individuals with an underlying immunosuppressive condition. A 30-year-old female patient was admitted to our clinic with complaint of a hemorrhagic, crusted, exudative vegetative two plaques on the scalp. On her physical examination, she had a prematurely aged face, predominant lower lips, total tooth loss, frontal bossing, enlarged anterior fontanelle, marked scalp veins, micrognatia, depressed nasal bridge, short stature, growth retardation. She was diagnosed as GAPO syndrome as the result of her physical examination. Result of the biopsy taken from scalp was evaluated as pyoderma vegetans. And the diagnosis of pyoderma vegetans was established based on the correlate of both clinical and histopathologic findings. Pyoderma vegetans coexisting with GAPO syndrome has not been reported previously. Thus we wished to report it.
Incontinentia Pigmenti With Ocular Involvement: Two Cases
(Medecine Et Hygiene, 2012) Bilgili, S. G.; Karadag, A. S.; Karadag, R.; Akdeniz, N.; Bulut, G.; Calka, O.
Incontinentia pigmenti with ocular involvement: two cases: Incontinentia pigmenti (IP) is a rare, X-linked dominant disorder that presents at or soon after birth and presents with cutaneous signs and symptoms. Besides its typical skin signs presenting in all patients, central nervous system (CNS), ophthalmologic and dental involvement are encountered as well. In this report, we present two patients at the verrucous stage of IP and review the literature concerning the diagnosis and course of IP.
Ocular Pulse Amplitude and Retrobulbar Blood Flow Change in Dipper and Non-Dipper Individuals
(Nature Publishing Group, 2011) Karadag, R.; Keskin, U. C.; Koktener, A.; Selcoki, Y.; Hepsen, I. F.; Kanbay, M.
Purpose To evaluate ocular pulse amplitude (OPA), IOP values, and hemodynamic changes in the ophthalmic artery, central retinal artery, and short posterior ciliary artery in dipper and non-dipper patients. Methods A total of 59 right eye measurements of healthy subjects with normotensive were included to the study. Ambulatory blood pressure (BP) monitoring measurement (ABPM), Doppler imaging, and OPA measurements were performed in the same day. The patients in which systolic BP decreased during the nocturnal time by 10% of the diurnal BP or more were called dippers. A patient whose nocturnal systolic BP fell by < 10% or even rose was defined as non-dipper. Color Doppler imaging was used for blood flow velocity assessment of ophthalmic, central retinal, and posterior ciliary arteries. For each artery, peak systolic and end-diastolic velocities (PSV and EDV, respectively), resistive index (RI), and pulsalite index (PI) were automatically calculated by the machine. Mean IOP and OPA values were calculated after three consecutive measurements. Results The mean OPA in non-dipper patients was significantly lower compared with that of dipper patients (P = 0.011). There was no significant difference in IOP levels between groups. There was no significant difference in the PSV, EDV, RI, and PI in the ophthalmic, posterior ciliary, and central retinal arteries between the groups. Conclusion Our study demonstrated that OPA level in non-dippers is lower than dippers. This may give additional information about the effect of BP changes on OPA values. Eye (2011) 25, 762-766; doi:10.1038/eye.2011.50; published online 18 March 2011
Trocar-Assisted Sutureless Intrascleral Posterior Chamber Foldable Intra-Ocular Lens Fixation
(Nature Publishing Group, 2012) Totan, Y.; Karadag, R.
Purpose We report a novel technique characterized by sutureless scleral fixation of three-pieces foldable intraocular lens (IOL) using 25-gauge transconjunctival sutureless vitrectomy (TSV) trocars in patients with insufficient posterior capsule support. Materials and Methods We performed this technique on the eight eyes of the seven patients. The scleral tunnels (STs) are prepared by insertion of the 25-gauge TSV microcannulas using the trocars, and anterior vitrectomy is performed through the clear corneal paracentesis with the aid of anterior chamber maintainer (ACM). Finally, the three-piece foldable IOL haptics are incarcerated into the prepared STs. Results The patients were followed up 5-8 months. None of the patients had complications such as postoperative endophthalmitis, glaucoma, IOL tilt or decentralization, and retinal detachment. Injection of a foldable IOL through a clear corneal small incision also contributes the less surgical-induced astigmatism. Conclusion The presented novel sutureless scleral IOL fixation technique may provide minimal trauma to the surrounding tissues, good IOL stabilization decreasing the incidence of IOL tilt along with shorter operation time, and postoperative quiet eye. Eye (2012) 26, 788-791; doi:10.1038/eye.2012.19; published online 2 March 2012