Browsing by Author "Karakas, Hilal"

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Chronic Pain in Multiple Sclerosis: a Two-Year Longitudinal Study
(Sage Publications Ltd, 2023) Karakas, Hilal; Ozdogar, Asiye Tuba; Ozcelik, Sinem; Kahraman, Turhan; Ozakbas, Serkan
Cognitive Impairment Is Associated With Chronic Neuropathic Pain
(Sage Publications Ltd, 2023) Karakas, Hilal; Ozdogar, Asiye Tuba; Sagici, Ozge; Samadzade, Ulvi; Kahraman, Turhan; Ozakbas, Serkan
Comparison of Early-Onset and Very Early-Onset People With Multiple Sclerosis Based on Cognitive and Physical Assessments
(Sage Publications Ltd, 2023) Kaya, Ergi; Ozdogar, Asiye Tuba; Karakas, Hilal; Sagici, Ozge; Ozakbas, Serkan
Correlation Between Lesion Loads and Cognitive, Social Cognitive, and Physical Measures in Persons With Multiple Sclerosis
(Sage Publications Ltd, 2023) Aslan, Taha; Ozdogar, Asiye Tuba; Sagici, Ozge; Karakas, Hilal; Ozakbas, Serkan
Development of Restless Legs Syndrome Severity Prediction Models for People With Multiple Sclerosis Using Machine Learning
(Sage Publications Ltd, 2023) Ozdogar, Asiye Tuba; Emec, Murat; Dastan, Seda; Karakas, Hilal; Baba, Cavid; Ozcanhan, Mehmet Hilal; Ozakbas, Serkan
Effect of Telerehabilitation-Based Motor Imagery Training on Pain and Related Factors in People With Multiple Sclerosis: a Randomized, Controlled, Assessor-Blinded Trial
(Sage Publications Ltd, 2023) Karakas, Hilal; Kahraman, Turhan; Ozdogar, Asiye Tuba; Sagici, Ozge; Baba, Cavid; Ozakbas, Serkan
Effect of Telerehabilitation-Based Motor Imagery Training on Pain and Related Factors in People With Multiple Sclerosis: Randomized Controlled Pilot Trial
(W B Saunders Co-elsevier inc, 2025) Karakas, Hilal; Kahraman, Turhan; Ozdogar, Asiye Tuba; Baba, Cavid; Ozakbas, Serkan
Objectives: To investigate the effect of telerehabilitation-based graded motor imagery (MI, GMI) training on pain and pain-related factors in people with multiple sclerosis (MS). Design: Randomized controlled, assessor-blind pilot trial with repeated-measure design. Setting: Neurology outpatient clinic. Participants: Thirty-two people with MS were randomly allocated to intervention (n=16) and control (n=16) groups. Interventions: During the 8-week GMI training period, the first 2 weeks involved implicit MI training while 6 weeks of explicit MI training were conducted. Main Outcome Measures: The primary outcome was the general pain intensity over the past 2 days, assessed with a visual analog scale, with a minimum clinically important difference (MCID) of 23 mm. Secondary outcomes included general pain and specific body parts' pain intensity over the past 7 days, neuropathic pain intensity, MI ability, fatigue, depression, anxiety, quality of life, sleep quality, daytime sleepiness, and cognitive functions scores. Assessments were conducted at baseline, at weeks 8 (post-treatment) and 12 (follow-up). Results: The intervention group demonstrated a significant reduction in pain intensity over the past 2 days compared with control group (P<.05). Furthermore, at the 8-week assessment, the intervention group surpassed the MCID in pain intensity over the past 2 and 7 days (P<.05), whereas no significant change was observed in the control group (P>.05). Significant effects were observed post-treatment on general pain over the past 7 days, neuropathic pain, MI ability, fatigue, depression, quality of life, processing speed, and visuospatial memory within intervention group compared with control group (P<.05). However, the effect on anxiety, sleep quality, daytime sleepiness, and verbal memory between groups was not significant (P>.05). Conclusions: Telerehabilitation-based GMI training stands out as viable for the management of chronic pain and pain-related psychosocial symptoms for people with MS.
Factors Affecting Motor Imagery Ability in People With Multiple Sclerosis
(Sage Publications Ltd, 2023) Karakas, Hilal; Kahraman, Turhan; Ozdogar, Asiye Tuba; Baba, Cavid; Ozakbas, Serkan
Factors Explained the Objective and Subjective Cognitive Fatigue in People With Multiple Sclerosis
(Sage Publications Ltd, 2023) Karakas, Hilal; Ozdogar, Asiye Tuba; Sagici, Ozge; Ozakbas, Serkan
Factors Related To Restless Leg Syndrome in Neuromyelitis Optica Spectrum Disorder
(Elsevier Sci Ltd, 2025) Ozdogar, Asiye Tuba; Karakas, Hilal; Dastan, Seda; Kaya, Ergi; Sagici, Ozge; Ozcelik, Sinem; Ozakbas, Serkan
Objective: Although the feeling of unrest in the legs is frequently reported as a sensory symptom by people with Neuromyelitis Optica Spectrum Disorder (NMOSD, pwNMOSD), there are limited studies to investigate the relationship between Restless Legs Syndrome (RLS) and NMOSD. The study's primary aim is to determine the frequency and severity of RLS in pwNMOSD. The other aim is to compare the sleep quality, daytime sleepiness level, quality of life, fatigue, magnetic resonance imaging results, and cognitive functions in RLS-positive and negative pwNMOSD. Methods: The RLS diagnosis was performed with RLS-Diagnostic Index criteria. The patient-reported outcomes were RLS Severity Rating Score, The Preference-Based Multiple Sclerosis Index (PBMSI), the Modified Fatigue Impact Scale (MFIS), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS). Cognitive function was assessed with The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) battery. The neurologist recorded the demographic and clinical characteristics of the participants. Results: The RLS was detected in 17 (21.5 %) of the 79 pwNMOSD participants. Fifty-six pwNMOSD were reached to assess cognitive functions and patient-reported outcomes. The rate of RLS was 60.71 % in this group. The PBMSI, PSQI, MFIS, and ESS scores were significantly different in RLS-positive participants than in RLS-negative (p < 0.05). Moreover, while participants' visuospatial and verbal learning was similar, the processing speed was slow in the RLS-positive group (p > 0.05). Conclusions: Our preliminary results have shown that the RLS frequency is high in pwNMOSD. This study suggests a connection between the presence of RLS and worse sleep quality, fatigue level, processing speed, and quality of life in the NMOSD population. However, our results should be considered with the fact that the study has a small sample size and needs future studies to confirm our results for solid evidence.
Identifying the Related Factors With Restless Legs Syndrome in Persons With Multiple Sclerosis
(Sage Publications Ltd, 2023) Ozdogar, Asiye Tuba; Karakas, Hilal; Aldemir, Enes; Dastan, Seda; Ozcelik, Sinem; Cilingir, Vedat; Ozakbas, Serkan
Revolutionizing Multiple Sclerosis Treatment: Unleashing the Power of the Symbol Digit Modalities Test To Optimize Cognitive Function
(Sage Publications Ltd, 2023) Sagici, Ozge; Karakas, Hilal; Ozdogar, Asiye Tuba; Baba, Cavid; Ozakbas, Serkan