Browsing by Author "Karakaya, C."
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Conference Object Cytokine Levels in the Seminal Plasma of Fertile and Infertile Men(Blackwell Publishing, 2006) Sayilir, N.; Tarakcioglu, M.; Karakaya, C.Article Effects of Applied Electrical Field on Biochemical Parameters and Erythrocytes of Rats(Mrs Pushpa Agarwal, 2006) Demir, H.; Cakir, T.; Karakaya, C.; Ilhan, A. Cebi; Onursal, N.; Gur, A.The purpose of this study was to determine whether there was any effect of some biochemical parameters and erythrocyte carbonic anhydrase on electrical field stimulation in female rat. The experiments were performed under the animals' scientific procedures and conform to National Institute of Health guidelines for the use of experimental animals. This study was carried out on female Sprague-Dawley rats (250-270 g). Comparasons were made using student-t tests. A p value less than 0.001 was considered statistically significant. It was demonstrated that alanine aminotransferase, aspartate aminotransferase, amylase and lactate dehydrogenase in serum were significantly affected by this electric field stimulation (p < 0.001). In addition, particularly carbonic anhydrase activity was affected by applied electrical field.Article Serum Il-6 and Crp Levels in Patients With Trauma Involving Low-Extremity Bone Fractures(2013) Karakaya, C.; Noyan, T.; Ekin, S.; Babayev, E.Cytokines and acute phase proteins have been implicated in the systemic response to trauma. The aim of this study was to measure the IL-6, CRP, ALP, calcium and phosphorus levels in patients with trauma involving low-extremity bone fractures at 6, 24 and 48 hours following trauma. Serum samples were obtained from 21 trauma patients with femoral or tibial fractures at 6th, 24th and 48th hour following trauma. Serum IL-6, CRP, ALP, calcium and phosphorus levels were measured in these samples. Serum levels of IL-6, CRP and ALP at 24th hour were found to be significantly elevated in comparison to their levels at 6th hour (p=0.01, p<0.01 and p<0.05, respectively). Moreover, the levels of CRP and ALP were found to be significantly elevated at 48th hour compared to their levels at 6th hour (p<0.01). However, serum IL-6 levels at 48th hour were found to be lower than the levels at 6th hour (p<0.01). There was not a significant correlation between CRP and IL-6 levels at different time points. Serum calcium and phosphorus levels did not change significantly. We have demonstrated that IL-6 reached its peak level in 24 hours after trauma and its level in the 48th hour decreased below that of 6th hour. CRP, as an acute phase reactant, increased for the first 24 hours and stayed elevated for the next 24 hours. Further studies should be conducted to demonstrate the correlation between the extent of injury and IL-6 and CRP levels.Conference Object The Serum Interleukin 6 and C-Reactive Protein Levels in the Patients After Trauma(Blackwell Publishing, 2006) Karakaya, C.; Noyan, T.; Sayilir, N.; Ekin, S.
