Browsing by Author "Karakok, M"

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Comparison of Thickness Measurements in Cutaneous and Subcutaneous Lesions Preoperatively (By Ultrasonography) and Postoperatively (By Ruler)
(Springer verlag, 1998) Bekerecioglu, M; Arslan, H; Ugras, S; Karakok, M; Akpolat, N
Vertical thickness of cutaneous and subcutaneous lesions cannot be assessed accurately by simple examination. To achieve this ultrasonography was performed preoperatively and ruler assessment postoperatively. These measurements were then compared and evaluated using the Wilcoxon test. The results were not statistically significant (p=0.6592, z=0.4410). Cutaneous and subcutaneous ultrasonography is a simple, quick, accurate method of assessing lesion thickness.
Effect of Intra-Articular Administration of Hyaluronan and Cortisone on Secondary Osteoarthritis of the Infected Rabbit's Knee
(Tohoku Univ Medical Press, 2001) Karakok, M; Ugras, S; Tosun, N; Fuat, A; Aydin, A
Hyaluronan is known to play an important role in the healing of degenerative osteoarthritis. But there is no clear consensus how it effects on osteoarthritis compare to cortisone. The purpose of the research was to determine the comparative effects of hyaluronan and cortisone on the healing of degenerative osteoarthritis. A rabbit model used in which & degenerative osteoarthritis were created in the articular cartilage by the inoculation of Staphylococcus Aureus (S. Aureus). The rabbits divided into two groups namely injected with hyaluronan (group A) and cortisone (group B) at days 20, 23 and 26. After hyaluronan and cortisone injections for treatment of osteoarthritis at day of 25 and 35 six rabbits (each of three injected with hyaluronan and cortisone) and at day 50 (six of injected with hyaluronan and five of cortisone) were sacrified. In biopsies obtained from these knees both articular cartilage degeneration and inflammation around the joint were examined by light microscopy. It was seen that the histopathologic findings were consistent with active chronic inflammation at day 10, followed by chronic inflammation. At day 5 of treatment the degeneration decreased (60%) in group A, and clinical findings disappeared after day 9 of treatment. At day 15 of hyaluronan treatment the degeneration degree regressed and at day 30 absolutely healed (all except :)ne). In group B, at day 5 of treatment, the clinical findings disappeared and the healing rate was 72%. At day 15 of cortisone treatment, the degeneration slightly increased and at day 30 the degeneration degree increased more than that day of 15. The results showed that cortisone is effective in the treatment of cartilage degeneration and inflammation early in the course of the septic arthritis whereas the therapeutic effect of hyaluronan is higher late in the course of the disease. Further studies are required in order to understand the effectiveness of the combined or consecutive use of these drugs in degenerative osteoarthritis.
Hydatid Disease in a Thyroglossal Cyst
(Assoc Soc Scientifique Med Belges, 1997) Ugras, S; Demirtas, I; Akdeniz, H; Kutluhan, A; Akpolat, N; Karakok, M
The location of hydatid disease in organs other than the liver and lung is unusual and occasionally producing difficulties in diagnosis. Thyroglossal cyst itself is not so common, so that more careful search of thyroglossal cyst for the presence of scolex and/or laminated membrane may result in increase in frequency of such a condition in the area where hydatid disease is prevailed. Since we were unable to find a case of hydatid disease involving thyroglossal cyst, as in our present case, we feel justified in reporting this case, considering it would be the first publication in world literature.
Immunohistochemical Study on Histogenesis of Congenital Epulis and Review of the Literature
(Blackwell Science, 1997) Ugras, S; Demirtas, I; Bekerecioglu, M; Kutluhan, A; Karakok, M; Peker, O
Congenital epulis is a very rare lesion found only in newborn infants. This tumor is multiple in about 10% of reported cases, rarely with the simultaneous involvement of the maxilla and mandibula, as in this article. In the presented case, light microscopy demonstrated large eosinophilic granular cells arranged in solid nests that are separated by thin fibrovascular areas. The tumors in the maxilla and mandibula were investigated with a panel of polyclonal and monoclonal antibodies, and using immunoperoxidase methods on formalin-fixed, paraffin-embedded sections. Immunohistochemical studies revealed strong and diffuse cytoplasmic staining for neuron specific enolase and vimentin. However, all other reactions were negative. These results suggest that the congenital epulis may be derived from uncommitted nerve-related mesenchymal cells.
Malondialdehyde Levels in Serum of Patients With Skin Cancer
(Springer, 1998) Bekerecioglu, M; Aslan, R; Ugras, S; Kutluhan, A; Sekeroglu, R; Akpolat, N; Karakok, M
The relationship of free radicals with some types of carcinomas is known, these studies have been performed on samples taken from the tumor tissue. In this study, the malondialdehyde levels in the serum of patients with skin cancer were studied and compared with a control group. The differences between malondialdehyde levels in these two groups were evaluated using Mann Whitney-U. There was a very statistically significant increase in malondialdehyde levels in serum of the skin cancer patients compared with the control group (p=0.0095, z=-2.59). Thus, increased serum malondialdehyde levels may be a sign of carcinoma.
Spinal Epidural Granulocytic Sarcoma (Chloroma) in a Non-Leukemic Child
(Blackwell Publishing Asia, 2001) Ugras, S; Cirak, B; Karakok, M; Guven, B