Browsing by Author "Karatas, Ceyhun"

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Synthesis of Some Metallophthalocyanines With Dimethyl 5-(phenoxy) Substituents and Evaluation of Their Antioxidant-Antibacterial Activities
(Pergamon-elsevier Science Ltd, 2015) Agirtas, M. Salih; Karatas, Ceyhun; Ozdemir, Sadin
The synthesis, characterization, spectral, antioxidant and antibacterial properties of dimethyl 5-(phenoxy)-isophthalate substituted Zinc, Cobalt, Copper, and Nickel phthalocyanines are reported. The novel compounds have been characterized by using electronic absorption, nuclear magnetic resonance spectroscopy, infrared, elemental analysis and mass spectrometry. The antioxidant and antibacterial activities of newly synthesized phthalocyanines and its starting material are tested. The DPPH free radical scavenging ability of phthalocyanine Co(II) and Zn(II) complexes on DPPH are 44.8% and 40.1% at 100 mg/L concentration, respectively. The phthalocyanine Co(II) and Cu(II) complexes show very strong ferrous ion chelating activity of 91.2% and 89.3% at concentration of 100 mg/L, respectively. Compound 3 displays strong reducing power like alpha-tocopherol. Antibacterial activities of phthalocyanine Co(II) and Amikacin (30 mu g/disk) against Micrococcus luteus (ATCC 9341) are 16 mm in diameter. (C) 2014 Elsevier B.V. All rights reserved.
Synthesis of Some Novel Phthalocyanines With Methyl 2-(oxy) Substituents, Evaluation of Their Antioxidant- Antibacterial Activities and Electronic Properties
(Wiley-v C H verlag Gmbh, 2015) Agirtas, M. Salih; Karatas, Ceyhun; Gumus, Selcuk; Okumus, Veysi
The synthesis, characterization, spectral, antioxidant, and antibacterial properties of methyl 2-(oxy)-2,2-diphenylacetate substituted metallophthalocyanines (4-7) are reported. A novel phthalonitrile, methyl 2-(2,3-dicyanophenoxy)-2,2-diphenylacetate (3) was prepared and characterized. The new compounds were characterized by using electronic absorption spectroscopy, nuclear magnetic resonance spectroscopy, infrared spectroscopy, and elemental analysis. All compounds were tested for their antioxidant activity by using 2,2-diphenyl-1-picrylhydrazyl radical scavenging ability, metal chelating, and reducing power. Furthermore, these compounds were screened for their in vitro growth inhibiting activity by disc diffusion method against four gram positive and two gram negative bacteria. The electronic data of the new compounds were obtained by computational calculations at B3LYP/6-31G(d,p) level of theory.
Synthesis, Aggregation Behavior, and Electronic Properties of Some Metallophthalocyanines With 2-Isopropyl Substituents
(Wiley-v C H verlag Gmbh, 2015) Agirtas, M. Salih; Karatas, Ceyhun; Gumus, Selcuk
The aim of this study was to perform facile synthesis of novel phthalocyanines with high solubility. The synthesis and characterization of 2-isopropyl-5-methylphenoxy substituted copper, zinc, nickel, and cobalt phthalocyanines are reported. The compounds were characterized by using electronic absorption, nuclear magnetic resonance spectroscopy, infrared and elemental analysis. The aggregation investigations carried out in different concentrations indicate that 2-isopropyl-5-methylphenoxy substituted phthalocyanine complexes do not have any aggregation behavior for the concentration range of 1x10(-5) to 1x10(-6) M in THF. Additionally, the ground-state geometries of the complexes were optimized using density functional theory methods at B3LYP/6-31G (d, p) level in order to obtain information about the 3D geometries and electronic structure.