Browsing by Author "Karayil, A.R."

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Analysis of Incidental Thyroid Cancers in Surgically Treated Toxic Goiter Patients
(Yuzuncu Yil Universitesi Tip Fakultesi, 2025) Aras, A.; Karayil, A.R.; Yilmaz, Ö.; Aras, I.; Toktaş, O.; Kotan, Ç.
Differentiated Thyroid Cancer (DTC) is the most common endocrine cancer and the frequency of DTC detection in histopathological examinations in thyroid surgeries performed for non-cancer indications is increasing. The aim of this study is to investigate the rate of incidentally detected thyroid cancer in patients who underwent surgery for toxic goiter in our clinic. Histopathological data of patients who underwent surgery with a diagnosis of toxic goiter were retrospectively reviewed. Patients were divided into 3 groups as toxic adenoma (TA), toxic multinodular goiter (MNG) and Basedow-Graves disease. The presence of malignancy and clinicopathological features were investigated RESULTS: 84% of the cases were female and 16% were male, and the mean age was 43. 202 (65%) of the toxic goiter cases had TMG, 8 (3%) had TA, and 101 (32%) had Graves' disease. Histopathologically, the malignant/benign ratio was 65 (21%)/ 246 (79%). Malignancy was detected in 3 of the 15 patients with a family history of thyroid cancer Incidental thyroid cancer was detected in 65 (21%) of the patients with toxic goiter. Thyroid carcinoma was present in 45 (22%) of the patients with toxic MNG, 1 (12.5%) of the patients with TA and 19 (19%) of the patients with Graves. Histopathological examination revealed 62 papillary (38 microcarcinoma), 2 Non-invasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (NIFTP) and 1 medullary microcarcinoma. The incidence of incidental thyroid cancer in the patients with toxic goiter treated with surgery was found to be consistent with the literature. © 2025, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Are Appendix Weight and Length Related To Inflammatory Parameters and Alvarado Score in Acute Appendicitis
(Yuzuncu Yil Universitesi Tip Fakultesi, 2021) Kiziltan, R.; Çalli, I.; Karayil, A.R.; Aras, A.; Kotan, Ç.
We aimed to investigate if appendix weight and length affects clinical presentation. This study prospectively enrolled 50 patients who were operated with the diagnosis of acute appendicitis. The appendix material was weighed in milligram. Then, the diameter of the appendix was measured in millimeter from its widest point using a surgical ruler. The length of the appendix was measured in millimeter using the same ruler. As appendix length may have influenced its weight, weight in milligram per millimeter was used for standardization. The obtained value was expressed as the unit weight (mg/mm). In order to make a comparison by the obtained unit weight, the patients were divided into two groups. Among 50 patients enrolled in the present study, 24 (48%) were men and 26 (52%) were women. The mean CRP level of the study population was 29.4 (3-160). The mean appendix diameter measured with ultrasonography at the preoperative period was 8.49 mm (range 6-13 mm), and the mean appendix diameter measured with a ruler at the postoperative period was 10.3 mm (range 8-20 mm). There was approximately a 2 mm difference between these measurements which were made from the widest points. In conclusion, it was found that the unit weight of the appendix increased proportionally to the CRP level. The appendix would be more edematous, have a greater diameter and weight, and be more likely to perforate in patients with a higher unit weight. © 2021, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.