Browsing by Author "Kaya, Bulent"

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The Prevalence of Brucellosis in Adults in Northeastern Region of Turkey
(Ahvaz Jundishapur Univ Med Sci, 2013) Arvas, Gulhan; Akkoyunlu, Yasemin; Berktas, Mustafa; Kaya, Bulent; Aslan, Turan
Background: Brucellosis is prevalent in the Mediterranean basin, the Indian subcontinent, the Arabian peninsula, and in parts of Central Asia, Africa, Central and South America. However it continues to be one of the major health problems in developing countries, including Turkey. Objectives: The current study aimed to determine the incidence of brucellosis, which is previewed to be very common in the northeastern region of Turkey, in order to emphasize the problem. Materials and Methods: Seroprevalence of brucellosis was examined in sera of 2913 patients who referred to Igdir State Hospital between February and December of the year 2010 by Standard Tube Agglutination Test method. Results: Results were statistically evaluated using chi-square trend analysis method. Significantly high level (1/40 dilution) of specific antibodies were detected in 525 (18 %) patient sera (P = 0.111). Conclusions: We hope that Turkey will be one of the brucellosis-free countries in near future with highlights from the current and further studies.
The Prevalence of Rotavirus and Adenovirus in the Childhood Gastroenteritis
(Kowsar Publ, 2016) Ozsari, Tamer; Bora, Gulhan; Kaya, Bulent; Yakut, Kahraman
Background: Acute gastroenteritis stemming from viral causes is very common during the childhood period. Rotavirus and enteric adenovirus are the most common factors of acute gastroenteritis encountered in infants and children. However, the epidemiology of rotavirus and enteric adenovirus gastroenteritis in the east Anatolia region is not well-known. Objectives: We aimed to evaluate the relationship between the distribution of antigen positivity in rotavirus and enteric adenovirus antigen tests required cases and demographic data retrospectively in pediatric patients admitted to our hospital. Patients and Methods: The records of stool sample analyses for 1154 patients admitted to our hospital from June 2011 to December 2011 with complaints of diarrhea were retrospectively examined. The presence of rotavirus and enteric adenovirus antigens in stool specimens was investigated by means of an immunochromatographic test. Results: Viral antigens were detected in 327 (28.3%) stool specimens out of 1154. Among the positive results, the frequency was 73.7% for rotavirus and 26.2% for adenovirus. While the detected rotavirus antigen rate was high for all age groups, it was highest for children under the age of 2, with a rate of 57.1%. Moreover, the rotavirus infections were observed at a rate of 44.3% in winter and of 24.6% in autumn. Conclusions: The most important factor in childhood acute gastroenteritis in east Anatolia is the rotavirus. Rotavirus and adenovirus antigens should be routinely investigated as a factor in fresh stool samples for the accurate diagnosis and treatment of gastroenteritis in children in the winter and autumn months.
The Seroprevalance of Acute Hepatitis a in 0-18 Age Group Children Who Applied To Igdir State Hospital
(Aves Yayincilik, Ibrahim Kara, 2011) Aryas, Gulhan; Kaya, Bulent; Berktas, Mustafa
Objective: Hepatitis A is one of the most widely known infections in the world and has a significant role in the etilogy of hepatitis. Human beings are the principal reservoirs. The Hepatitis A prevalence is higher in children in developing countries. This study aims to detect acute hepatitis A seroprevalance in children between 0-18 years who applied to Igdir State Hospital from Feb 2010-Dec 2010. Material and Method: The existence of anti-HAV IgM antibodies has been examined in seras separated from blood samples taken from 990 children, whose ages range between 0-18, using Vitros ECI Q J&J Company Ortho Clinical Diagnostic macro ELISA device. The results have been evaluated according to age, gender and seasons using chi-square trend analysis. Results: In this study, the overall seroprevalance of anti-HAV IgM has been found to be 18.1%, 19.6% for girls and 17.0% for boys (p=0.304). In terms of age groups, the positivity rate is 2.1% in the 0-6 age group, 12% in the 6-12 age group and 3.7% in 12-18 aged children (p<0.001). On the other hand, the seasonal positivity rate has been determined as 4% between Februrary and June, 3.1% between June and September and 10.9% between Sept-Dec (p=0.002). Discussion: The positive results were evaluated statistically according to age groups and genders. The difference between the statistical analysis yielded no significance in terms of gender. However, the disease was most significnatly seen in the 6-12 age group which involves to primary school age. Seasonally, it was mostly detected between the Sept-Dec period. Coclusion: It is suggested that necessary precautions should be taken in order to prevent sewage water intermingling with drinking water during the time of vaccination for pre-school children and seasons of frequent rainfall.
Seroprevalence of Rubella in Northeastern Turkey
(Springer Wien, 2013) Akkoyunlu, Yasemin; Arvas, Gulhan; Ozsari, Tamer; Hakyemez, Ismail Necati; Kaya, Bulent; Aslan, Turan
Aim The aim of this study was to search rubella prevalence and compare the results with national and international data. Materials and methods The presence of anti-rubella immunoglobulin G (IgG) and anti-rubella immunoglobulin M (IgM) antibodies were studied in the sera obtained from cases with fever in last week and applied to the Microbiology Laboratory in the period between February 2010 and December 2010. No clinical sign or symptom regarding rubella infection has been evaluated for cases to obtain blood samples. IgM and IgG antibodies were tested with ELISA (Vitros ECI Q (J&J) Company Ortho Clinical Diagnostic Macro) method. The data obtained were assessed with SPSS statistical package using chi-square trend analysis method. Results Anti-rubella IgM positivity was found 6/68 (8.8%) of males and 3/138 (2.2%) of females who are under 18 years-old (p = 0.028). Meanwhile 47/65 (72.3%) of males and 99/122 (81.8%) of females under 18 years-old were presented with anti-rubella IgG positivity (p = 0.164). In all, 2/8 (25 %) males and 28/1,181 (2.4 %) females older than 18 years-old were anti-rubella IgM positive (p = 0.013). Anti-rubella IgG antibodies were found positive in 862/1,181 (73 %) of females and all males (8/8) older than 18-years-old (p = 0.086). Conclusions In spite of the active immunization programme commenced after 2006, rubella infection is still a risk in Turkey without discriminating the gender.