Browsing by Author "Kaya, N."

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Development of a Cobalt Tetra (Diethoxycarbonylmethyl) Phthalocyanine-Based Benzydamine-Selective Poly Vinyl Chloride Membrane Potentiometric Sensor
(John Wiley and Sons Inc, 2026) Kanberoğlu, G.S.; Kaya, N.; Aǧirtaş, M.S.
Benzydamine (BNZ) overdose can lead to serious adverse effects, including hallucinations, urticaria, bronchospasm, and renal dysfunction. Therefore, its selective and sensitive determination is essential. In this study, a novel potentiometric sensor for BNZ was developed using cobalt tetra(diethoxycarbonylmethyl)phthalocyanine (CoPc) as the ionophore. The surface morphology of the sensor was confirmed by scanning electron microscopy (SEM). The developed sensor exhibited a Nernst slope of 59.6 mV/decade in the concentration range of 1.0 × 10−8−1.0 × 10−2 M, a detection limit of 9.5 × 10−9 M, a fast response time of 10 s, and stable performance in the pH range of 2.10–8.00. It demonstrated a 34-day operational lifetime and high selectivity, with stability further confirmed by water layer tests and potential drift measurements. Successful application in pharmaceutical formulations and physiological serum samples validated its practical utility. Compared to previously reported potentiometric sensors, this sensor offers a wider linear range and lower detection limit, providing a rapid, selective, and reliable tool for BNZ determination. © 2026 Wiley-VCH GmbH.
Development of a MOF-Based Oxytetracycline-Selective PVC Membrane Potentiometric Sensor
(John Wiley and Sons Inc, 2025) Kanberoğlu, G.S.; Kaya, N.
Oxytetracycline is widely used in veterinary medicine to protect animals from infections, treat existing conditions, and mitigate stress-related events such as vaccination, transportation, and medication. However, an overdose of oxytetracycline may lead to several adverse effects, including renal dysfunction, altered mental status, hepatotoxicity, and gastrointestinal disorders. Therefore, accurate determination of oxytetracycline is essential to ensure both therapeutic efficacy and patient safety. In this study, a polyvinyl chloride (PVC) membrane-based potentiometric sensor selective for oxytetracycline was developed using MIL-53 (Materials of Institut Lavoisier) as the ionophore. The optimal membrane composition consisted of 3% MIL-53, 64% nitrophenyloctylether (NPOE), 1% potassium tetrakis(4-chlorophenyl)borate (KTpClPB), and 32% PVC. The sensor exhibited a linear response in the concentration range of 1.0 × 10−2 to 1.0 × 10−⁷ M, with a Nernstian slope of 53.1 mV/decade. The pH working range was determined to be 4.56–11.00. It can be concluded that the developed solid contact potentiometric sensor offers satisfactory analytical properties. Analytical application of the sensor was successfully implemented in pharmaceutical formulations, physiological serum, and different water samples. © 2025 Wiley-VCH GmbH.
The Prevalence of Gynecomastia and Its Relationship With Age in 1589 Turkish Patients Who Underwent Ct Scans Due To Various Reasons
(Yuzuncu Yil Universitesi Tip Fakultesi, 2023) Kaya, N.; Aydın, M.A.; Kiziltan, R.
In this study, we aimed to contribute to the literature on the prevalence of gynecomastia and its relationship with age in Turkey by examining patients who underwent chest CT scans ordered for various reasons in male patients in our hospital. A total of 1589 male patients were included in our study. If a patient underwent multiple chest CT scans, only the first examination was used for the analysis. Patients’ age, presence of gynecomastia (GM) and laterality were recorded. Furthermore, the patients were divided into age decades. The correlations between GM, laterality and age decades were investigated. In CT examinations, GM was detected incidentally in 439 (27.6%) of the patients. Of all GMs, 234 (53.3%) were bilateral, 117 (26.6%) were left unilateral and 88 (20.0%) were right unilateral. GM peaked in the age range of 60-70 years and 70-80 years. A significant positive correlation was found between bilateral GM and age, (r=0.115, p<0.001). In our study, the prevalence of GM was found as 27.6%. Bilateral GMs were more common by 53.3%, while left unilateral GMs were more frequent. The prevalence of GM peaked to times in the age ranges o f 60-70 years and 4 70-80 years. There was a statistically significant correlation between bilateral GM and age. © 2023, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
A Study on Abu Mullet {liza Abu Heckel, 1843) (Diyarbakir), Turkey
(Medwell Journals, 2014) Elp, M.; Kaya, N.
In this study, population structure, growth and reproduction properties of Liza abu which lives in Devegecidi Dam Lake and its inlets were observed between November 2008 and January 2010 and totally 1005 individuals sampled. Maximum age, fork length and weight were determined as IV, 21.8 cm, 122 g, respectively. Sex ratio (male:female) was calculated as 1:0.94. Condition factor was found as 1.261 ±0.003. No any mature sample could be caught from the dam lake tributaries between April and July. At the same period abundantly mature samples could be caught from the dam lake. This situation has led to the opinion that reproduction go on in the dam lake. Fecundity was found 26393±1375 eggs per female and 538±21 eggs per gram gonad weight. The eggs diameters were calculated as 0.6±0.02 mm. © Medwell Journals, 2014.