Browsing by Author "Kebapci, Fatih"

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Authors' Reply To: Using Anterior Segment Optical Coherence Tomography To Compare the Smoothness of Anterior Iris Surface Between Two Eyes in Unilateral Fuchs' Uveitis Syndrome
(Springer, 2019) Ozer, Muhammet Derda; Kebapci, Fatih; Batur, Muhammed; Seven, Erbil; Tekin, Serek
Choroid Vascularity Index as a Parameter for Chronicity of Fuchs' Uveitis Syndrome
(Springer, 2020) Ozer, Muhammet Derda; Batur, Muhammed; Tekin, Serek; Seven, Erbil; Kebapci, Fatih
Purpose This study aimed to compare the choroidal vascularity index (CVI) of eyes having Fuchs' uveitis syndrome (FUS) with healthy fellow eyes (N). Methods This prospective, cross-sectional study included unilateral FUS cases and an age- and gender-matched healthy control group. Thirty-nine participants were included in the FUS group, and 24 age- and gender-matched individuals were randomly selected for the control group. Endothelial cell density (ECD) was measured using Tomey specular microscopy. Spectral-domain optical coherence tomography was used to acquire the choroidal images, and binarization was applied to the images. Two blinded investigators analyzed the CVI in both eyes of the FUS cases and the right eyes of the healthy control group. Results CVI was found to be significantly decreased in FUS (p < 0.001). Additionally, ECD had a strong positive correlation with CVI (r = 0.383, p = 0.008). Conclusion CVI may provide information about the chronicity of the disease.
The Depigmentation Degree of Iris Pigment Epithelium in Pseudoexfoliation Syndrome
(Elsevier, 2021) Ozer, Muhammet Derda; Batur, Muhammed; Tekin, Serek; Seven, Erbil; Kebapci, Fatih; Bilmez, Rumeysa
Background: To compare the optical density of iris pigment epithelium (ODIPE) and iris stromal thickness (IST) measurements in patients having pseudoexfoliation syndrome (PXS) and age-gender matched participants. Methods: This is a cross-sectional study. Patients with PXS were enrolled in the study group. Age and gendermatched healthy subjects with no evidence of PXS were recruited as controls. After a comprehensive ophthalmological evaluation, the anterior segment images were acquired using anterior segment spectral-domain optical coherence tomography (AS SD-OCT). The acquired pictures were further analyzed using the ImageJ program. Two investigators measured the ODIPE and the IST of the subjects, and the repeatability and reproducibility were checked. SPSS program was used for statistical analysis. Results: The PXS group was comprised of twenty-two eyes (n = 22 patients), and the control group contained twenty-six eyes of 26 age and gender-matched healthy subjects. The mean temporal ODIPE of the study group was found to be decreased significantly in comparison to the mean temporal ODIPE of the control eye (p = 0.018). Both the mean nasal (N) and temporal (T) ISTs of the PEX eyes were thinner than the control eyes (p = 0.006 and p = 0.002, respectively). The mean baseline IOP was found to significantly negatively correlate with the ODIPE in the PEX group at both N and T sides (r = -0.531, p = 0.011 and r = -0.685, p < 0.001, respectively). Conclusion: The pupillary margin IPE was found more depigmented, and the mean N and T IST were significantly thinner in the PEX group by comparison with the age-gender matched healthy controls. The mean baseline IOP was negatively correlated with the pupillary margin's IPE pigmentation degree in patients with PXS.
In Vivo Analysis and Comparison of Anterior Segment Structures of Both Eyes in Unilateral Fuchs' Uveitis Syndrome
(Springer, 2019) Ozer, Muhammet Derda; Kebapci, Fatih; Batur, Muhammed; Seven, Erbil; Tekin, Serek
PurposeTo compare corneal endothelial cell density (ECD), iris stromal thickness (IST), iris pigment epithelium optical density (IPE OD), and Schlemm's canal (SC) measurements in patients having unilateral Fuchs' uveitis syndrome (FUS).MethodsThis is a randomized, prospective study. Currently, diagnosed unilateral FUS and phakic cases were defined to be the inclusion criteria to the study. The specular microscope was used to measure ECD. Anterior segment images were acquired by using SD-OCT. The images were extracted and uploaded to the ImageJ program for further analysis. Two blinded investigators analyzed the IST, IPE OD, and SC area in both healthy (N) and affected eyes (FUS) and the comparative analysis was made by using SPSS program.ResultsOf twenty-one participants, 13 were female (62%). The mean age of the participants was 309 (18-47) years. ECD was 2228 +/- 365 and 2513 +/- 209cells/mm(2) in the FUS and N, respectively (p<0,001). In FUS, the mean nasal and temporal (n-t) IST was measured as 380 +/- 44 and 347 +/- 41m, compared to 393 +/- 61 and 355 +/- 62m in N, respectively (p=0.3 and p=0.4 respectively). The mean n-t IPE OD was measured as 1110 +/- 499 and 937 +/- 370 in FUS, compared to 1147 +/- 528 and 1267 +/- 428 in N, respectively (p=0.008 temporal). The mean n-t SC area was measured as 5479 +/- 1951 and 5624 +/- 2722m(2) in FUS, compared to 5736 +/- 2574 and 5633 +/- 1835m(2) in N, respectively (p=0.9 and p=0.7 respectively).Conclusion Decreased ECD in FUS may lead to serious complications after cataract surgery. Temporal IPE depigmentation occurs prior to the nasal side in FUS.
In Vivo Analysis and Comparison of Anterior Segment Structures of Both Eyes in Unilateral Herpetic Anterior Uveitis
(Taylor & Francis inc, 2021) Ozer, Muhammet Derda; Batur, Muhammed; Seven, Erbil; Tekin, Serek; Kebapci, Fatih
Purpose: To compare the Schlemm's canal area (SCA) and to define iris features in patients with unilateral herpetic anterior uveitis (HAU) by using anterior segment spectral-domain optical coherence tomography (AS SD-OCT). Methods: Unilateral HAU cases that had been in complete remission for >= 3 months were included. Two investigators analyzed the iris features of HAU. SCA in both healthy (N), and affected eyes (HAU) were compared. Results: The mean age of the participants (n = 22) was 36.3 +/- 15 (17-70) years. The mean nasal and temporal (n-t) SCA was measured as 10,844 +/- 4806 mu m(2)and 8,772 +/- 3138 mu m(2)in HAU in comparison with 10,200 +/- 4,824 mu m(2)and 10,045 +/- 3,889 mu m(2)in N, respectively (p= .47 andp= .12, respectively). The most common iris features were the sectoral iridoplegia (100%) on biomicroscopy and the disorganization of the iris layers (DIL) (77%) on AS SD-OCT images. Conclusion: SCA found similar on both sides. DIL is the most common iris feature of affected eyes.