Browsing by Author "Keskin Tunc, Serap"

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Can Extracorporeal Shock Wave Therapy Be Effective in Temporomandibular Joint Disorder?: a Pilot Study
(Lippincott Williams & Wilkins, 2024) Keskin Tunc, Serap; Unalan Degirmenci, Beyza; Bilen, Mustafa; Toprak, Mehmet Emin; Kaplan, Sehmus; Turan, Mahfuz
Background:This study aimed to compare extracorporeal shock wave therapy (ESWT) with the use of stabilization splint in nonsurgical temporomandibular disorders treatments, and to evaluate the effects.Methods:In this study, individuals, who are diagnosed with disc displacements with reduction according to the diagnostic criteria for temporomandibular disorder examination criteria. The patients in the first control group (n = 36) were applied a medical treatment + stabilization splint. The second group (n = 25) was applied the ESWT (2 days a week for 4 weeks) + medical treatment + stabilization splint. Visual Analog Scale scores, painless maximum painless mouth opening, and passive-forced mouth opening measurements were recorded for the first and second weeks.Results:The ESWT application significantly contributed to pain-reducing (Visual Analog Scale) in patients at short notice (P = .030) in the second group. There were statistically significant differences between the groups in painless maximum active mouth opening (P = .009) and passive forced measurements (P = .004) in the second week.Conclusion:This pilot study showed that short-term ESWT addition to stabilization splint and medical treatment may yield satisfactory outcomes.
Comparative Evaluation of the Effects of Diclofenac Sodium and Vitamin D Supplementation on Symptoms in Individuals With Myofascial Pain and Vitamin D Deficiency: A Randomized Controlled Clinical Trial
(BioMed Central Ltd, 2025) Kahraman, Nazlı Hilal; Keskin Tunc, Serap
Background: Temporomandibular joint disorders are significant health issues characterized by dysfunctions in the masticatory muscles and the temporomandibular joint. These disorders are often associated with stress, oral parafunctions, and habits such as bruxism. Treating bruxism and other parafunctional habits can reduce symptoms of myofascial pain. While the etiology of bruxism remains unclear, psychological factors like stress and anxiety, along with central nervous system, are thought that it will provoke. Additionally, a significant relationship has been reported between low serum vitamin D levels and bruxism. The aim of this study is to comparatively evaluate the effectiveness of nonsteroidal anti-inflammatory drug treatment and vitamin D supplementation on symptoms in individuals with myofascial pain and vitamin D deficiency. Methods: This study included patients aged 18–40, diagnosed with myofascial pain (MP) according to DC/TMD criteria, and individuals with vitamin D deficiency. Two different treatment methods were applied to the patients. One group received medical treatment with diclofenac sodium and an occlusal splint. The other group received vitamin D supplementation and an occlusal splint. The patients’ mouth opening and pain scores were evaluated at four stages; before treatment, and 1 week, 4 weeks, 12 weeks after the initiation of treatment. Results: The study ultimately included 40 participants, with 20 patients per group. Of the participants, 3 (7.5%) were male and 37 (92.5%) were female. At the end of the study, the changes in mouth opening and VAS scores were homogeneous in both groups. Conclusions: Vitamin D may serve as an alternative with anti-inflammatory and analgesic effects compared to NSAIDs. Trial registration: This randomised trial was approved by the Van Yüzüncü Yıl University Faculty of Medicine Clinical Research Ethics Committee (May 18, 2022, decision no: 05). The trial was registered with the Clinical Trial Registry (Number and date: NCT06111573, 10/31/2023). © 2025 Elsevier B.V., All rights reserved.
Erbium, Chromium-Doped: Yttrium, Scandium, Gallium, Garnet and Diode Lasers in the Treatment of Peri-Implantitis: Clinical and Biochemical Outcomes in a Randomized-Controlled Clinical Trial
(Springer London Ltd, 2022) Alpaslan Yayli, Nazli Zeynep; Talmac, Ahmet Cemil; Keskin Tunc, Serap; Akbal, Damla; Altindal, Dicle; Ertugrul, Abdullah Seckin
This study aims to evaluate the effects of 940 nm diode laser and 2780 nm erbium, chromium-doped: yttrium, scandium, gallium, garnet (Er,Cr:YSGG) laser used in addition to mechanical therapy in the non-surgical treatment of peri-implantitis on clinical parameters and matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) levels in the peri-implant crevicular fluid. A total of 50 patients with peri-implantitis were randomized into three groups to receive peri-implant treatment. The control group (n = 17) only received conventional non-surgical mechanical therapy. The trial groups [(diode group (n = 16) and Er,Cr:YSGG group (n = 17)] received dental laser in addition to mechanical therapy. Gingival index (GI), plaque index (PI), bleeding on probing, probing depth (PD), MMP-9, and TIMP-1 levels were assessed at baseline (T0) and at 6 months after treatment (T1). The GI, PI, and PD significantly decreased in all groups at T1, compared to T0 (p < 0.05). The decrease in the PD was similar between the control and diode groups with Er,Cr:YSGG providing more reduction (1.16 +/- 0.64 mm) than either method (p = 0.032). A significant intra-group decrease in MMP-9 level was only observed in the Er,Cr:YSGG group (p = 0.009). The decrease in TIMP-1 level from T0 to T1 was similar between the control and the diode groups (p > 0.05) and it was significantly lower than the decrease in the Er,Cr:YSGG group (p < 0.05). Addition of diode laser to non-surgical mechanical therapy does not provide any additional benefit for treatment outcomes. The Er,Cr:YSGG laser seems to be more efficient both at clinical and molecular levels.