Browsing by Author "Kesli, Recep"

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Hepatitis C Testing Among Adults Born Between 1945 and 1965 in Turkey: a Multicentre Study
(Natl inst Public Health, 2018) Altindis, Mustafa; Demiray, Tayfur; Koroglu, Mehmet; Atasoy, Ali Riza; Kesli, Recep; Tosun, Selma; Guducuoglu, Huseyin
Objective: Hepatitis C virus (HCV) infection is a major public health problem and affects large populations all over the world. Serum anti-HCV level is a valuable marker to determine HCV infection. Anti-HCV testing has been recommended for high-risk population. The Center for Disease Control (CDC) and Prevention in the United States proposed a new high-risk population group - adults born between 1945-1965. Under this perspective, we designed a multicentre retrospective study to determine the seropositivity of anti-HCV among adults born between 1945 and 1965 and adults born after 1965 in Turkey. With the data collected, we aimed to determine whether there was a need for anti-HCV testing especially in people born between 1945 and 1965. Methods: We requested data from ten different medical centres in ten different provinces. Each medical centre collected the anti-HCV test results of adult patients for five-year period between 2009 and 2014 from hospital records. Results: A total of 974,449 anti-HCV test results were included in this study. When the seropositivity rates in the two groups of adults were compared, anti-HCV seropositivity rates were higher in nine medical centres out of ten. Anti-HCV seropositivity in adults born between 1945-1965 was significantly higher than in adults born after 1965 (p <0.05). Conclusions: We determined that the anti-HCV seropositivity rate is significantly higher in adults born between 1945-1965 compared to the younger adults as indicated in the literature. According to data from this study together with the WHO and CDC suggestions, we believe that it is appropriate to offer anti-HCV serology testing for people over 50 years of age since the anti- HCV seroprevalence in this age group is relatively high.
The Relationship of Hepatitis C Seroprevalence and Age, Sex, and Hemodialysis Time of Patients Undergoing Hemodialysis
(Galenos Yayincilik, 2006) Kurtoglu, Muhammet Guzel; Bozkurt, Hamza; Kesli, Recep; Berktas, Mustafa
In the present study which investigates the effect of hemodialysis time to hepatit C virus (HCV) seroprevalence, sera belonging to 216 patients treated with hemodialysis from three centers were used as materials. Microparticle Enzyme Immune Assay (MEIA) and chemiluminescence assays were used to investigate anti-HCV antibodies in patients sera and the obtained results were recorded. The relationship among sex, age and hemodialysis time of the patients and the obtained results were investigated. It was established that anti-HCV positivity is 23.2% in men and 14.4% in women, and mean HCV seroprevalence is 19%. The mean age of the patient is 47.8 +/- 17.3 year, mean dialysis time is 47.8 +/- 42.5 month. In conclusion, while there is not any relationship among anti-HCV positivity, sex and the age of patients, there was statistically important relationship between anti-HCV positivity and beginning time to dialysis (r=0.501, p=0.0001).