Browsing by Author "Kiliçalp, D"

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The Effects of Carbon Tetrachloride (Ccl4) Induced Experimental Acute and Chronic Intoxication on Histological Structure of Liver and Some Hematological Values and Electrocardiogram in Rabbits
(Scientific Technical Research Council Turkey, 1999) Çinar, A; Yörük, M; Meral, I; Kiliçalp, D; Koç, A; Ertekin, A
This paper reports an investigation of the effects of acute and chronic carbon tetrachloride intoxications on the histologic structure of the liver and hematological values and electrocardiograms in rabbits. The rabbits were divided into 3 groups of 7. The first group was the control group, the second group was acutely intoxicated and the third group was chronically intoxicated. In the acutely intoxicated group, caryorexsis, along with necrosis was observed in the hepatocyte of the centrolobular area of the liver. In the chronically intoxicated group, connective tissue mass around the V. centralis increased. This increase of connective tissue caused chirrosis. Hematological values of the groups were as follows: red blood cells 5.86+/-0.6, 5.95+/-1.5, 4.26+/-0.7 billion/mm(3); white blood cell: 6.9+/-1.35, 5.90+/-0.8, 4.0+/-2.44 thousand/mm(3); hemoglobin concentration: 12.7+/-0.9, 13.6+/-1.5, 11.8+/-1.2 gr/dl; hematocrit value: 41.8+/-3.3, 44.6+/-4.9, 33.0+/-4.4%; sedimentation: 5.2+/-1.6, 8.0+/-2.8, 10.2+/-1.3 45 degrees/1 hours respectively. The formula leukocyte was as follows: in the control group: neutrophil 34+/-5.3%, eosinophil 0.6+/-0.8%, basophil 0.2+/-0.4%, lymphocyte 62+/-5.02%, monocyte 3.2+/-0.97%. In the acutely intoxicated group: neutrophil 7.75+/-1.1%; eosinophil 1+/-0%; basophil 0+/-0%; lymphocyte 88.5+/-1.3%; monocyte 3.5+/-1.8%. In the chronically intoxicated group: neutrophil 60+/-8.51%; eosinophil 1+/-0.71%; basophil 0+0%: lymphocyte 35.75+/-7.33%; monocyte 3.2+/-0.83%. The extremity leads and 2 vertical and 1 horizontal chest leads were used in the electrocardiograph of the rabbits, All waves were observed in all derivations. The P and T waves were negative in the III and aR leads and positive in the other leads, The amplitudes of waves decreased (hypo voltage) as a result of intoxication. In the groups, the heart rates were 219+/-21 in the control. 215+/-17 in the acutaly intoxicated, 201+/-35 per minute in the chronically intoxicated and the mean electrical axes of the heart rate were 45 degrees+/-20, 50 degrees+/-27. 35 degrees+/-20 respectively. Statistical comparisons were carried out using analysis of variance and Q test.
Investigation of the Effects of Age, Sex and Season on Electrocardiographs (Ecg Values) and Heart Radiographs of Healthy Van Cats
(Scientific Technical Research Council Turkey, 2003) Kiliçalp, D; Çinar, A
This study was carried out to investigate the effects of age, sex and season change on electrocardiograms of Van cats. Thirty-eight (male and female) healthy Van cats, 3-15 months old were used. Electrocardiograms (ECGs) and heart radiographs were obtained from cats seperately in summer, autumn, winter and spring. ECGs were recorded as bipolar, augmented unipolar and precordial leads (CV6LL, CV6LU, V-10). Durations and amplitudes of waves on the trace were measured in lead II and the electrical axis also measured in leads I and III. Radiographic examination was performed in the right lateral recumbency position (covering the whole thoracic cavity) and the dose of the X-ray beam was 44-47 kV. The duration of P wave was 0.04 s. and its amplitude was 0.10 mV-0.12 mV. The PR interval was 0.06-0.08 s. The duration of the QRS complex was 0.03-0.04 s and its amplitude was 0.16 mV-0.5 mV. The duration of the T wave was 0.06-0.09 s. and its amplitude was 0.1 mV-0.15 mV. The duration of the QT interval was 0.15-0.18 s. The T wave was negative in all of the aVR leads and in some of leads 11, aVL and V4. The mean electrical axis of the cats was +66.5degrees to +87.5degrees. No significant differences were seen among the groups. The heart rate in the first group was determined by seasons to be 200 +/- 12(a), 170 +/- 5.9(b), 193.2 +/- 12(a) and 207.2 +/- 15(a) beat/min (a,b: P < 0.05); in the second group 201 +/- 8.7, 179.8 +/- 5.1, 202.8 +/- 14 and 195.6 +/- 5.2 beat/min; in the third group 176.2 +/- 7.7, 170 +/- 7, 186.6 +/- 13 and 193.5 13 beat/min; and in the fourth group 186.3 +/- 16, 180 +/- 14, 200 +/- 11 and 210 +/- 15 beat/min, respectively. According to radiographic examinations. the heart was located 4(th) - 7(th) and 5(th) - 7(th) intercostal intervals.
Possible Association Between Chronic Laminitis and Some Biochemical Parameters in Dairy
(Australian veterinary Assn, 2004) Belge, F; Bildik, A; Belge, A; Kiliçalp, D; Atasoy, N