Browsing by Author "Kilicalp, Dide"

Now showing 1 - 2 of 2

Effects of Green Tea on Electrocardiography of Guinea Pigs Exposed To Electromagnetic Field Emitted by Mobile Phones
(Kafkas Univ, veteriner Fakultesi dergisi, 2009) Kilicalp, Dide; Deger, Yeter; Cinar, Ali
This study was carried out to determine the effects of green tea on Electrocardiography (EKG) of Guinea pigs exposed to a 900 MHz electromagnetic field emitted by mobile phones. Because green tea has a beneficial effect on endothelial function, tea consumption is associated with decreased cardiovascular risk. Twenty-eight healthy guinea pigs weighing 600-800 g were used. After one week adaptation period, animals were randomly divided into four groups. Four experimental groups labeled as controls (Group A), irradiated (Group B), irradiated receiving green tea extract (Group C) and green tea only (Group D) were formed with seven randomly chosen animals. Group A and D were housed in a separate room without exposing EMF of mobile phones. Irradiation was accomplished by exposing the animals in Group B and C to a 900 MHz electromagnetic field from a 217-Hz pulse rate, 2-W maximum peak power mobile phone placed in the cage were the animals were kept. ECG of guinea-pigs in four groups was recorded by a direct writing electrocardiograph at the end of the 30-day experimental period during exposure to mobile phone. Sinus bradycardia (lower heart beat) and prolongation of the P-R interval was observed in Group B and C after exposure to electromagnetic field (P<0.05). Whereas the heart rate in the green tea extract supplemented group was close to the control group's level, it was found to have been the lowest in the only irradiated (Group B). We found measurable effects in the heart rate and P-R interval parameters in the EM-exposed guinea pigs. It was found that EMF exposure for 30 days have some effects on ECG findings of guinea-pigs. The results suggest that exposure of guinea pigs to EM fields can cause disturbances in autonomic cardiac regulation.
Effects of X-Ray Radiation on Oxidation Products of Nitric Oxide in Rabbits Treated With Antioxidant Compounds
(Walter de Gruyter Gmbh, 2009) Dede, Semiha; Deger, Yeter; Kahraman, Tahir; Kilicalp, Dide
Objectives: The aim of this study was to investigate the effect of supplemental antioxidant vitamins and minerals on the nitric oxide oxidation products nitrite and nitrate in rabbits after exposure to X-rays. Methods: The animals were divided into two experimental, one control group. The vitamin-supplemented group was given daily oral doses of vitamins E and C. Supplemental amounts of manganese, zinc, and copper were mixed with the feed and given to the mineral-supplemented group. Blood samples were taken from all groups before and after 4 weeks of vitamin and mineral administration and after irradiation with 550-rad X-rays. The nitric oxide oxidation products levels were analyzed in blood serum. Results: After irradiation, the control group showed increased levels of nitric oxide oxidation products (p<0.05). In the vitamin group, the concentration of nitric oxide oxidation products was lower (p<0.05) when compared to controls. In the MG, the mineral treatment was not affected nitric oxide oxidation products, but, irradiation was increased nitrate levels. Conclusion: It is concluded that the elevated levels of nitrate and nitrite concentrations in serum is the result of damage caused by the x-ray radiation. The results suggest that supplementation with antioxidant vitamins and minerals may serve to reinforce the antioxidant systems, thus having a protective effect against cell damage by X-rays.