Browsing by Author "Kirimi, E."

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Acute Respiratory Distress Syndrome Due To Overdose Desferrioxamine: Report of a Child
(2005) Atas, B.; Caksen, H.; Tuncer, O.; Oner, A.F.; Kirimi, E.; Akbayram, S.
In this article, we present an 18-month-old girl with acute iron poisoning who died from acute respiratory distress syndrome due to overdose of desferrioxamine. Our purpose is to emphasize the importance of close follow-up of children with acute iron poisoning for desferrioxamine toxicity.
Bacillus Anthracis Sepsis in a Newborn
(Lippincott Williams and Wilkins, 2000) Özkaya, E.; Kirimi, E.; Berktas, M.; Odabaş, D.
Baller-Gerold Syndrome Associated With Dextrocardia
(Medecine Et Hygiene, 2011) Ceylan, A.; Peker, E.; Dogan, M.; Tuncer, O.; Kirimi, E.
Baller-Gerold syndrome associated with dextrocardia: Baller-Gerold Syndrome (BGS) is a rare autosomal recessive disorder that is apparent at birth. The disorder is characterized by distinctive malformations of the skull and facial area and bones of the forearms and hands. We report a 4 year old boy in whom the clinical features of craniosynostosis and bilateral absent thumbs and radii led to a diagnosis of Baller-Gerold syndrome. Physical examination revealed that the heart was localized to the right side. Echocardiography confirmed dextrocardia. Dextrocardia has not previously been reported with Baller-Gerold syndrome. To the best of our knowledge, this is the first reported case of Baller-Gerold syndrome associated with dextrocardia.
A Case of Bartter’s Syndrome Associated With Nephrocalcinosis Presenting With Tetany
(2004) Ataş, B.; Çaksen, H.; Tuncer, O.; Kirimi, E.; Arslan, S.; Erol, M.; Yuca, S.A.
A 10-year-old boy was admitted to hospital with a 3 month history of intermittent spasms of the wrists and ankles, and twitching of the eyelids. He also had polyuria, polydipsia, nocturnal enuresis, fatigue and constipation since he was a toddler. Physical examination revealed normal blood pressure, myokymia on the right eyelid and bilateral carpopedal spasms. Laboratory investigation revealed hypocalcemia, hypokalemia, increased plasma renin and aldosterone, hypercalciuria, metabolic alkalosis, and bilateral medullary nephrocalcinosis. Cranial computed tomography was normal. Based on the clinical and laboratory findings he was diagnosed as having Bartter’s syndrome, which is characterized by hypochloremia, hypokalaemia and metabolic alkalosis associated with potassium renal leakage, with normal blood pressure despite increased plasma renin activity. It is well known that tetany is not uncommon in the neonatal form of Bartter’s syndrome and nephrocalcinosis is usually not present in the classic form. Interestingly, our patient had both the clinical manifestations of the neonatal form and of the classic form of Bartter’s syndrome. In conclusion, we would like to emphasize that both the clinical manifestations of neonatal and classic forms of Bartter’s syndrome (as an overlapping syndrome) might be seen in children and that Bartter’s syndrome should also be considered in children with tetany as in our case. © 2004, IOS Press. All rights reserved.
Comparison of Cerebral Oximeter and Pulse Oximeter Values in the First 72 Hours in Premature, Asphyctic and Healthy Newborns
(Univ West indies Faculty Medical Sciences, 2014) Kaya, A.; Okur, M.; Sal, E.; Peker, E.; Kostu, M.; Tuncer, O.; Kirimi, E.
Aim: The monitoring of oxygenation is essential for providing patient safety and optimal results. We aimed to determine brain oxygen saturation values in healthy, asphyctic and premature newborns and to compare cerebral oximeter and pulse oximeter values in the first 72 hours of life in neonatal intensive care units. Methods: This study was conducted at the neonatal intensive care unit (NICU) of Van Yuzuncu Yil University Research and Administration Hospital. Seventy-five neonatal infants were included in the study (28 asphyxia, 24 premature and 23 mature healthy infants for control group). All infants were studied within the first 72 hours of life. We used a Somanetics 5100C cerebral oximeter (INVOS cerebral/somatic oximeter, Troy, MI, USA). The oxygen saturation information was collected by a Nellcor N-560 pulse oximeter (Nellcor-Puriton Bennet Inc, Pleasanton, CA, USA). Results: In the asphyxia group, the cerebral oximeter average was 76.85 +/- 14.1, the pulse oximeter average was 91.86 +/- 5.9 and the heart rate average was 139.91 +/- 22.3. Among the premature group, the cerebral oximeter average was 79.08 +/- 9.04, the pulse oximeter average was 92.01 +/- 5.3 and the heart rate average was 135.35 +/- 17.03. In the control group, the cerebral oximeter average was 77.56 +/- 7.6, the pulse oximeter average was 92.82 +/- 3.8 and the heart rate average was 127.04 +/- 19.7. Conclusion: Cerebral oximeter is a promising modality in bedside monitoring in neonatal intensive care units. It is complementary to pulse oximeter. It may be used routinely in neonatal intensive care units.
Comparison of Low and High Dose of Vitamin D Treatment in Nutritional Vitamin D Deficiency Rickets
(Freund Publishing House Ltd, 2003) Cesur, Y.; Çaksen, H.; Gündem, A.; Kirimi, E.; Odabaş, D.
In this study, we compared three different therapy modes (150,000 IU, 300,000 IU, and 600,000 IU vitamin D p.o.) in infants with nutritional vitamin D deficiency rickets (VDR). Our purpose was to determine the most effective dosage of vitamin D with least side effects for treating VDR. The study included 56 patients, 3-36 months of age, with nutritional VDR and 20 age-matched control infants. In all infants, serum calcium, phosphorus, alkaline phosphatase, magnesium, serum 25-hydroxycholecalciferol, plasma intact parathormone levels and urinary Ca/creatine ratio were determined. Of 56 patients, 52 were able to be followed long-term. These patients were reexamined on the 3rd day, 7-10th day, and 25-30th day after treatment. On the 30th day post-treatment, we did not find any difference between the doses in the improvement of rickets. However, hypercalcemia was present in eight infants who had been administered 300,000 IU (two infants) and 600,000 IU (six infants) of vitamin D. In conclusion, our findings showed that 150,000 IU or 300,000 IU of vitamin D was adequate in the treatment of VDR, but 600,000 IU of vitamin D may carry the risk of hypercalcemia.
Comparison of Various Treatments in Childhood Brucellosis
(2006) Yuca, S.A.; Ceylan, A.; Çaksen, H.; Kirimi, E.; Yilmaz, C.; Bay, A.
The aim of this study was to evaluate the effectiveness of different drug combinations for treatment of brucellosis in children. Sixty children (mean age 9.2 ± 3.1 years, range 10 months to 15 years) were treated with four different drug combinations. The diagnosis of brucellosis was established by positive serum agglutination titer, and/or the isolation of Brucella species from blood cultures. The most frequent findings were fever and arthritis in 12 (20%) and 13 (21.6%) patients respectively. The children under 8 years old comprised Group 1 and 2, and older than 8 years comprised Group 3 and 4 according to treatment regimens. Nine patients (Group 1) were treated with trimethoprim-sulfamethoxazole (TMP-SMZ) for 45 days plus ceftriaxone for 5 days and, rest nine patients (Group 2) were managed with TMP-SMZ for 45 days plus gentamicin for 5 days. Twenty-one patients (Group 3) were managed with doxycycline for 45 days and ceftriaxone for 5 days and, other 21 (Group 4) patients were managed with doxycycline for 45 days and gentamicin for 5 days. All patients recovered. Relapse and improvement rates were similar for all groups (P >0.05). Each regimen was effective in the treatment of childhood brucellosis. Using cheaper drugs such as doxycycline and gentamicin in children 8 years of age and older, and TMP-SMZ and gentamicin in children 7 years of age or younger for the treatment of brucellosis in children is a practical and useful approach in our region and in the developing countries. © 2006 - IOS Press and the authors.
Congenital Primary Hypothyroidism Associated With the Rare Form of Nonimmune Hydrops Fetalis
(2010) Yuca, S.A.; Cesur, Y.; Kirimi, E.; Sari, S.; Kaya, A.; Doǧan, M.
We present a male newborn born with diffuse edema and ascites. A diagnosis of congenital primary hypothyroidism was made based on thyroid hormone levels of total T4 1.74 μg/dL, free T4 0.30 ng/dL and TSH >75 μIU/mL and thyroid hormone replacement therapy was initiated. At day 15 of therapy, the thyroid function tests of the patient reached normal limits, and his edema and ascites regressed. In this report we present a newborn case of hypothyroidism that was accompanied by nonhydrops fetalis. We want to emphasize that congenital hypothyroidism may present with severe symptoms such as hydrops.
Esophageal Atresia Concomitant With Congenital Hypothyroidism and Phenylketonuria in a Newborn
(Walter de Gruyter GmbH, 2010) Peker, E.; Tuncer, O.; Cagan, E.; Dogan, M.; Kaya, A.; Aveu, S.; Kirimi, E.
Giant Cavernous Hemangioma in Two Neonates With Kasabach-Merritt Syndrome: Successful Management With Interferon Alpha and Prednisolone
(Blackwell Publishing, 2008) Kirimi, E.; Tuncer, O.; Akgun, C.; Ceylan, A.
Hallermann Streiff Syndrome
(Wiley-blackwell, 2008) Tuncer, O.; Kirimi, E.; Demir, H.; Caksen, H.; Gulmemet, F.
Increased Serum Malondialdehyde Level in Neonates With Hypoxic-Ischaemic Encephalopathy: Prediction of Disease Severity
(Sage Publications Ltd, 2010) Kirimi, E.; Peker, E.; Tuncer, O.; Yapicioglu, H.; Narli, N.; Satar, M.
Increased serum level of malondialdehyde (sMDA) in neonates with hypoxic-ischaemic encephalopathy (HIE) was evaluated as a possible criterion for determining HIE severity. Mean body weight and gestational age in a healthy control group of neonates (n = 63) and in neonates with HIE (n = 69) were statistically similar. Apgar scores at 1 and 5 min for the HIE group were significantly lower than for the control group. The mean sMDA level for the HIE group was significantly higher than the control group. Within the HIE group, the sMDA level for neonates with Sarnat's grade II and III was significantly higher than for those with Sarnat's grade I. There was a significant correlation between Sarnat's grading and the sMDA level. The sMDA level was significantly higher for neonates who died (n = 20) compared with those who survived (n = 49). In conclusion, the sMDA level was highest in neonates with HIE and correlated with HIE severity. The sMDA concentration could, therefore, be used as a criterion for predicting disease severity.
Joubert Syndrome Associated With Patent Ductus Arteriosus in a Newborn Infant
(Medecine Et Hygiene, 2009) Peker, E.; Kirimi, E.; Sal, E.; Ceylan, A.; Ustyol, L.; Caksen, H.
Management of Respiratory Distress of Newborn
(2007) Kirimi, E.
Respiratory distress are more often seen in the newborn period specially in premature infants because of immature lungs than other life period of children. Respiratory distress that becomes manifested by tachypnea, intercostal retractions, cyanosis, expiratory grunting, and nasal flaring is a nonspecific response to serious illness. Not all of the disorders producing neonatal respiratory distress are primary diseases of the lungs. The differential diagnosis of respiratory distress includes pulmonary, cardiac, hematologic, infectious, anatomic, and metabolic disorders that may involve the lungs directly or indirectly. Surfactant deficiency causes RDS, resulting in cyanosis and tachypnea; infection produces pneumonia, shown by interstitial or lobar infiltrates; meconium aspiration results in a chemical pneumonitis with hypoxia and pulmonary hypertension; bronchopulmonary dysplasia or chronic lung disease of newborn causes prolonged tachypnea, oxygen dependency and fibrosis shown in chest graph. Transient tachypnea of newborn or wet lung is a benign course for newborn. It also is clinically useful to differentiate the common causes of respiratory distress according to gestational age. All these disorders have been reviewed in the light of last literatures.
Powder Topical Rifampicin on Reducing Infections After Neural Tube Defect (Ntd) Surgery in Infants
(Springer, 2016) Demir, N.; Peker, E.; Gulsen, I.; Kocaman, S.; Tuncer, O.; Kirimi, E.
Rubella Seroprevalence in Adolescent Girls in the Eastern Region of Turkey
(2002) Çaksen, H.; Ceylan, A.; Ceylan, N.; Arslan, S.; Öner, A.F.; Kirimi, E.; Gölbasi, C.
Thanatophoric Dysplasia Type I: Case Report
(Blackwell Publishing, 2008) Kirimi, E.; Bektas, S.; Ceylan, A.; Gulmehmet, F.