Browsing by Author "Kiroglu, Ahmet Faruk"

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The Effect of Nitrous Oxide on the Outcomes of Underlay Tympanoplasty: a Prospective Study
(Sage Publications inc, 2019) Duzenli, Ufuk; Bozan, Nazim; Turan, Mahfuz; Agirbas, Semra; Tekeli, Arzu Esen; Kiroglu, Ahmet Faruk
The main aims of tympanoplasty are eradication of chronic middle ear disease, repair of the tympanic membrane, and restoration of hearing. Nitrous oxide (N2O) is not a commonly preferred anesthetic agent for tympanoplasty because this agent may increase middle ear pressure and displace the graft. In this study, we researched the surgical outcomes of the underlay tympanoplasty performed with N2O anesthesia. Patients who underwent tympanoplasty were included in this prospective study. A type 1 tympanoplasty was performed in all patients using the underlay technique. Patients were randomized to groups that did and did not receive N2O. Preoperative and postoperative hearing thresholds were evaluated, postoperative pain scores were recorded, and the differences between the groups were statistically evaluated. There were 44 patients who received N2O and 44 who did not. The graft success rate was 93.2% in the N2O-receiving group and 84.1% in the nonreceiving group (P > .05). Hearing levels improved significantly after surgery in each group (P < .05), but the difference between the groups was not significant (P > .05). The postoperative pain score was 3.72 +/- 1.3 in the N2O-receiving group and 4.45 +/- 2.3 in the nonreceiving group (P > .05). Nitrous oxide is a cheap, safe, and readily available anesthetic agent that provides acceptable success rates in patients undergoing tympanoplasty.
Etiological and Epidemiological Factors in Hearing-Impaired Students in Van, East of Turkey: a Case Series
(Pakistan Medical Assoc, 2017) Kiroglu, Ahmet Faruk; Ari, Muzaffer; Bozan, Nazim; Parlak, Mehmet; Cankaya, Hakan
The aim of the present case series was to investigate the causes of hearing loss in the children studying at a primary School for the deaf in Van Province, Turkey. The present series included 95 children with sensorineural hearing loss. Otoscopic and ophthalmological examinations, pure-tone audiometry, and tympanometry were performed for each patient. Measles IgG, rubella IgG, cytomegalovirus (CMV) IgG, toxoplasma IgG, herpes simplex virus (HSV) Type I (HSV-I) IgG, HSV Type II (HSV-II) IgG, and Mycoplasma pneumonia IgG were evaluated in serum samples. Temporal bone anomalies were analyzed on temporal bone computed tomography (CT). A total of 7 radiologically distinct inner ear malformations were detected in 19 children. Twelve children were detected with various fundus pathologies. The most common cause of hearing loss was family-related factors (52%). In conclusion, the etiological and epidemiological factors were consistent with those reported in the literature.
Gradenigo Syndrome Induced by Suppurative Otitis Media
(Lippincott Williams & Wilkins, 2018) Bozan, Nazim; Duzenli, Ufuk; Yalinkilic, Abdulzaziz; Ayral, Abdurrahman; Parlak, Mehmet; Turan, Mahfuz; Kiroglu, Ahmet Faruk
Gradenigo syndrome was defined as a clinical triad of otitis media, severe orbito-facial pain, and ipsilateral sixth cranial nerve palsy. It may occur as a complication of either acute or chronic otitis media. Herein, we will report a case of Gradenigo syndrome induced by suppurative chronic otitis media that was promptly diagnosed and aggressively treated.
A Honey Bee Can Threat Ear: Sudden Sensorineural Hearing Loss
(W B Saunders Co-elsevier inc, 2017) Duzenli, Ufuk; Bozan, Nazim; Ayral, Abdurrahman; Yalinkilic, Abdulaziz; Kiroglu, Ahmet Faruk
Sudden sensorineural hearing loss is an otologic emergency. Many etiological factors can lead to this pathology. Honey bee (Apis mellifera) sting may lead to local and systemic reactions due to sensitization of the patient. In this paper we described a sudden sensorineural hearing loss occurred after honey bee sting. (C) 2017 Elsevier Inc. All rights reserved.
Lip Cancer: a 16-Year Retrospective Epidemiological Study in Eastern Part of Turkey
(Pakistan Medical Assoc, 2016) Bozan, Nazim; Kocak, Omer Faruk; Cankaya, Hakan; Kiroglu, Ahmet Faruk; Gur, Mehmet Hafit; Erten, Remzi
Objective: To review lip cancer patients with respect to age, gender, location and histological type of tumour, and risk factors. Methods: This retrospective study was conducted at the Yuzuncu Yil University, Van, Turkey, and comprised-medical records of the histologically confirmed lip cancer patients who presented between 1994 and 2010. No patient had neck nodes or evidence of distant metastasis. Results: Of the 91 patients 73(80.22%) were men and 18(19.78%) were women. The overall mean age was 62.32 +/- 13.88 years (range: 25 to 97 years). Histologically, the tumour was a squamous cell carcinoma in 81(89.01%) cases and a basal cell carcinomas in 10(10.99%) cases. Upon admission, the mean diameter of the tumour in squamous cell carcinoma patients was 2.03 +/- 1.23 cm and 1.87 +/- 1.29 cm in basal cell carcinoma patients. As for the tumour differentiation, 67(84.72%) of the squamous cell carcinoma cases were well differentiated, while 14(17.28%) were moderately differentiated. Conclusion: The incidence of lip cancer was found to be higher among men, while the histopathological type was mostly squamous cell carcinoma and well differentiated.
Mean Platelet Volume, Red Cell Distribution Width, and Neutrophil-To Ratio Before and After Surgery in Patients With Carotid Body Tumors
(Lippincott Williams & Wilkins, 2017) Bozan, Nazim; Kocak, Omer Faruk; Dinc, Mehmet Emre; Demir, Canser Yilmaz; Turan, Mahfuz; Kiroglu, Ahmet Faruk
Objective: Carotid body tumors (CBTs) are rare hypervascular benign tumors that originate from the paraganglia at the carotid bifurcation. The red cell distribution width (RDW), neutrophil-to-lymphocyte ratio (NLR), and mean platelet volume (MPV) may serve as markers in inflammatory, cardiovascular, and neoplastic diseases. However, their prognostic value in CBTs is unknown. The purpose of this study was to assess the leukocyte count, MPV, RDW, and NLR before and after surgery in patients with CBTs. Methods: This retrospective trial included data from 80 patients with CBTs and 65 age-matched healthy controls. The leukocyte, neutrophil, lymphocyte and platelet counts, RDW, and MPV were extracted and NLR was calculated from the complete blood count results of participants. Results: The leukocyte and neutrophil counts as well as RDW levels were significantly increased in patients with CBTs compared with healthy controls (P = 0.005, P = 0.003, and P = 0.026; respectively). Patients with CBTs had lower lymphocytes counts (P = 0.241) and higher NLRs (P = 0.054); however, the difference was statistically insignificant. Moreover, no statistically significant difference was detected between groups in terms of platelet counts and MPV levels. Furthermore, the leukocyte count, platelet numbers, MPV, RDW, and NLR levels in patients with CBTs were not statistically significant after surgery (all; P> 0.05). Conclusion: This is the first study that documents the increased RDW levels and leukocyte count in patients with CBTs. The combined use of RDW and the leukocyte count along with other clinical assessments can be used as a biomarker for CBTs. Further clinical trials with larger cases series are required to determine the actual predictive roles of these systemic biomarkers.
Mean Platelet Volume, Red Cell Distribution Width, Platelet-To and Neutrophil-To Ratios in Patients With Ankylosing Spondylitis and Their Relationships With High-Frequency Hearing Thresholds
(Springer, 2016) Bozan, Nazim; AlpaycAñ, Mahmut; Aslan, Mehmet; Cankaya, Hakan; Kiroglu, Ahmet Faruk; Turan, Mahfuz; Ilter, Server
The mean platelet volume (MPV), red cell distribution width (RDW) and neutrophil-to-lymphocyte ratio (NLR) comprise laboratory markers in ankylosing spondylitis (AS). There is a controversy in the literature regarding which type of ear involvement is characteristic of AS. The aim of this study was to simultaneously investigate the MPV, RDW, platelet to lymphocyte (PLR) and NLR in patients with AS and their relationships with high-frequency hearing thresholds. Thirty patients with AS and 35 age-matched healthy subjects were included. Each subject was tested with low- (250, 500, 1000 and 2000 Hz) and high- (4000, 8000, 10,000, 12,000, 14,000 and 16,000 Hz) frequency audiometry. Additionally, the case and control groups were evaluated regarding the average hearing thresholds in bone conduction. The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels were measured. The RDW, MPV, neutrophils, lymphocytes and platelet counts were evaluated with the complete blood count. Furthermore, the NLR and PLR were calculated. The complete blood count, platelet numbers, ESR, CRP and NLR levels were significantly increased in the AS patients compared with the healthy controls (p < 0.001, p = 0.007, p < 0.001, p < 0.001 and p = 0.047, respectively). There was no statistically significant difference in the RDW, PLR or MPV levels (p > 0.05) in the AS patients compared with the healthy controls. The BASDAI score and disease duration were not correlated with the ESR, CRP levels, MPV, PLR, RDW or NLR in patients with AS (all; p > 0.05). The AS patients had increased average measurement values for the hearing threshold in both ears at frequencies of 250, 500, 1000 and 2000 Hz; however, there was no statistically significant difference (p > 0.05). The average values of the hearing threshold in both ears at the high frequencies of 4000, 6000, 8000, 10,000, 12,000 and 14,000 Hz were significantly increased in the case group; however, it was not significantly increased at 16,000 Hz. The current study is the first to investigate the PLR, NLR, MPV and RDW levels in acute AS. We identified a significantly increased NLR, leukocyte count, ESR and CRP in AS patients. Sensorineural hearing loss, especially at extended high frequencies, is common in patients with AS and may represent an extra-articular feature of the disease. The combined use of NLR with the leukocyte count and other clinical assessments may facilitate the diagnostic process of ankylosing spondylitis.
Meatal Obstruction Following Canal Wall Down Mastoidectomy
(Pakistan Medical Assoc, 2017) Bozan, Nazim; Duzenli, Ufuk; Kundi, Pinar; Turan, Mahfuz; Kiroglu, Ahmet Faruk
Chronic otitis media (COM) is completely treated with a single procedure in most patients but may require multiple surgeries in some cases. The main goals of open cavity mastoidectomy are to completely eradicate the disease, create a large enough meatus for examination and mastoid air cells, and provide a self-cleaning epithelized dry cavity, and achieve maximum hearing. In this report, we present a very rare case of COM who underwent revision mastoidectomy in our clinic due to meatal obstruction in the right ear, total sensorineural hearing loss, and pain and tenderness in the postauricular region.
Pediatric Inverted Papilloma of the Middle Ear: Case Report and Review of the Literature
(Elsevier Ireland Ltd, 2014) Ulkumen, Burak; Kaplan, Yunus; Kiroglu, Ahmet Faruk; Bayram, Irfan
Inverted papilloma of middle ear is a very rare clinical entity. It has been reported only in the adult population. We report a middle ear inverted papilloma in an 11-year-old male. To the best of our knowledge it is the first pediatric inverted papilloma of middle ear. The patient had a history of chronic suppurative otitis media and the lesion was found during preoperative evaluation for a tympanoplasty procedure. Total excision of the lesion and a tympanoplasty operation was accomplished. We reviewed the middle ear inverted papilloma cases regarding the age distribution, pathophysiology, treatment and prognosis. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
Reconstruction of the Columella Using the Prefabricated Reverse Flow Submental Flap: a Case Report
(Wiley, 2006) Tan, Onder; Kiroglu, Ahmet Faruk; Atik, Bekir; Yuca, Koksal
Background. The reconstruction of columellar defects is still a challenging procedure because of limited local and regional flap options and the characteristics of the anatomy of this site. Although a number of methods are available to repair nasal columella defects, no treatment of choice ensuring an excellent texture and color-matched tissue in one stage has been determined to date. Method. In this case, we used a reverse-flow submental island flap prefabricated with the costal cartilage for the reconstruction of a complex columellar defect. Result. The flap survived completely with reversible venous congestion, The cosmetic result and nasal respiratory function were acceptable during the follow-up time of 6 months. Conclusion. We propose that the prefabricated reverse submental flap may be an alternative among the surgical options for columellar defects, This flap may also be considered in the reconstructive repertoire of other composite defects of the head and neck region, (c) 2006 Wiley Periodicals, Inc.
Serum Trace Elements and Heavy Metal Levels in Patients Diagnosed With Chronic Otitis Media and Their Association With Surgical Treatment Outcomes
(Aves, 2017) Bozan, Nazim; Dinc, Mehmet Emre; Demir, Halit; Yalinkilic, Abdulaziz; Gonullu, Edip; Turan, Mahfuz; Kiroglu, Ahmet Faruk
OBJECTIVE: To determine the serum iron (Fe), zinc (Zn), manganese (Mn), copper (Cu), magnesium (Mg), cobalt (Co), and lead (Pb) levels in patients with chronic otitis media (COM) and to evaluate the association of the serum levels of these elements with treatment outcomes. MATERIALS and METHODS: Thirty-one healthy volunteers and 31 patients with COM were prospectively included in this study. Serum levels of Fe, Zn, Mn, Mg, Cu, Co, and Pb were determined by an atomic absorption UNICAM-929 spectrophotometer. RESULTS: Serum Co, Pb, and Fe levels were significantly increased (p<0.001) and serum Cu, Zn, Mg, and Mn levels were significantly reduced in patients with COM compared with controls (p<0.001). Serum Co and Mn levels were significantly decreased (p<0.001 and p<0.005, respectively) and serum Cu levels were significantly increased after surgery (p<0.005). The other evaluated blood chemicals and heavy metals did not exhibit significant differences (p>0.05). CONCLUSION: Significant alterations in the serum chemical composition of patients with COM were observed. Moreover, with surgical treatment, serum levels of some of these chemicals were significantly altered. Further prospective studies are warranted to elucidate the exact association of these alterations in the etiopathogenesis of COM.
Tympanic Membrane Perforation Caused by Thunderbolt Strike
(Lippincott Williams & Wilkins, 2016) Bozan, Nazim; Kiroglu, Ahmet Faruk; Ari, Muzaffer; Turan, Mahfuz; Cankaya, Hakan
Thunderbolt strike is a life-threatening entity. In the patients presenting with thunderbolt strike, the central nervous system and the cardiovascular system should be primarily evaluated, followed by tympanic membrane lesions. The most important symptom connected with ear is the loss of hearing. In this report, a 43-year-old male patient with unilateral tympanic membrane perforation, tinnitus, and bilateral sensorineural hearing loss caused by thunderbolt strike is presented through a review of the literature.