Browsing by Author "Kisli, M"
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Article Auditory Brainstem Potentials in Children With Protein Energy Malnutrition(Elsevier Ireland Ltd, 2005) Odabas, D; Çaksen, H; Sar, S; Tombul, T; Kisli, M; Tuncer, J; Yilmaz, CObjective: In this study, auditory brainstern potentials (ABPs) were studied in children with protein energy malnutrition (PEM) to determine the effects of PEM on the developing brain in children. Methods: A total of 31 children, aged 3-36 months with moderate/severe PEM and 25 healthy children, aged 3-48 months were included in the study. Nutritional status of the children was assessed by the Gomez classification. Recordings of ABPs were performed by using Nihon Kohden Neuropack 2 device. Results: Of 31 children, 22 (71%) had severe malnutrition, 9 (29%) had moderate malnutrition. Additionally, 8 (26%) and 9 (29%) children had iron deficiency anemia and hypoalbuminemi, respectively. There were significant differences in the mean latencies of the waves I-V on the right and left ears and in the mean interpeak latencies (IPLs) of the waves III-V and I-V on the right ear between the study and control groups (P < 0.05). The mean IPLs of I-V on the left side were found to be longer in the moderate PEM group than those of severe PEM group (P < 0.05). There was not any difference between the groups of PEM with low serum albumin and PEM with normal serum albumin. While the mean IPLs of I-III on the right side were found longer in the cases of PEM without iron deficiency anemia, the mean latency of wave I on the left side, and the mean IPLs of III-Von the right side were longer in the children with PEM plus iron deficiency anemia (P < 0.05). Conclusions: Our findings showed that children with moderate/severe PEM had ABPs abnormalities in different degrees, which reflect defects in myelination of auditory brainstem pathways in children with moderate/severe PEM. However, we found contradictory results between abnormalities in ABPs and degree of malnutrition and iron deficiency anemia. We think that more extensive studies should be performed to determine whether or not there was a relationship between these parameters. (c) 2005 Elsevier Ireland Ltd. All rights reserved.Conference Object Brucellosis Incidence in Subjects With Headache in Eastern Turkey(Dr Dietrich Steinkopff verlag, 2004) Anlar, O; Tombul, T; Akdeniz, H; Kisli, M; Kocturk, F; Caksen, HArticle Visual Evoked Potentials in Multiple Sclerosis Before and After Two Years of Interferon Therapy(Taylor & Francis Ltd, 2003) Anlar, O; Kisli, M; Tombul, T; Ozbek, HMagnetic resonance imaging (MRI) is important in the diagnosis of and follow-up for the treatment of multiple sclerosis (MS); evoked potentials may be important if MRI is normal or cannot be performed. We assessed serial visual evoked potentials (VEPs) and cranial MRI in a group of clinically relapsing-remitting multiple sclerosis (N = 15) treated with interferon beta-lb (INFB-1b) and in normal subjects (N = 15). The investigations were done I week before INFB-lb therapy, 1 year later (N = 15), and 2 years later (N = 10). VEPs were abnormal in most of the patients; MRIs were abnormal in all patients. We used P100 latency as an electrophysiological index for the progress of illness. There were significant differences in VEPs between the beginning and ending of the interferon treatment. We concluded that VEPs would be a reliable index for following up the progress of MS under interferon therapy.