Browsing by Author "Koca, Halil"

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Green Synthesis of 1-Methyl
(Health & Environment Assoc, 2021) Calis, Hatice; Koca, Halil; Kivrak, Arif
Indole and derivatives have emerged as central candidates for material chemistry since they show remarkable properties in solar cells. Many synthetic methods have been employed for the synthesis of indoles. Moreover, 3thiopehenylindoles could be play very critical roles for the synthesis of novel organic materials. In the present study, 1-methyl-2-phenyl-3-(thiophen-2-yl)-1H-indole is synthesized by using three different reaction ways including Suzuki-Miyaura coupling reaction, Stille coupling reaction and MW assisted cyclization reaction. It was investigated that microwave assisted green reaction could be best ways for the formation of 1-methyl-2-phenyl-3-(thiophen-2yl)-1H-indole.
Iodine-Catalyzed Oxidative Cyclizations for the Construction of Thienocarbazole Derivatives
(Amer Chemical Soc, 2017) Kivrak, Arif; Koca, Halil
Synthesis and Biological Properties of Novel 1-Methyl Hydrazine Analogues
(Tubitak Scientific & Technological Research Council Turkey, 2018) Kivrak, Arif; Yilmaz, Can; Konus, Metin; Koca, Halil; Aydemir, Selahattin; Oagaz, Jeger Ali
1-Methyl-2-(2-(prop-2-yn-1-yloxy)benzylidene)hydrazine analogues were readily prepared in good yields by the reaction of 2-(prop-2-yn-1-yloxy)benzaldehydes and methyl hydrazine. The reaction tolerates a variety of substituents on the 2-hydroxybenzaldehyde to form nitro-, halo-, methoxy-, and naphthyl-substituted 1-methyl-2-(2-(prop-2-yn-1-yloxy)benzylidene)hydrazines. The in vitro antioxidant capacity measurements revealed that among all the analyzed hydrazine analogues that surpassed the Trolox standard, 1-(2-(but-3-ynyl)-5-nitrobenzylidene)-2-methylhydrazine had the maximum value, which was approximately 1.7 times that of Trolox.