Browsing by Author "Konur, Sevki"

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Course of Acute Pancreatitis in the Elderly Evaluated With Computed Tomography Scan
(Gunes Kitabevi Ltd Sti, 2020) Konur, Sevki; Surmeli, Neslihan; Gunduz, Ihsan; Iliklerden, Umit Haluk; Dertli, Ramazan; Kayar, Yusuf
Introduction: In our study, we aimed to evaluate how age affects the severity and course of acute pancreatitis according to the modified Balthazar scoring system. Materials and methods: 354 patients diagnosed with acute-pancreatitis and followed-up in our hospital between July/2013-February/2019 were included our study. Demographic data, comorbid diseases and mortality rates of all patients were documented. Patients with aged 65 and over were assessed as geriatric population. All patients included in the study underwent contrast enhanced abdominal computed-tomography within the first 12 hours and on days 3 to 7. According to the modified Balthazar score, patients with mild, moderate and severe acutepancreatitis respectively. The relationship between age and computed-tomography findings was analyzed. Results: 206 (58.2%) of the patients included in the study were women. Mean age was 54.8 +/- 17.9 years (18-100 years). Geriatric population consisted of 129(36.5%) patients. There was no statistically significant difference between the two groups according to the modified Balthazar classification on the initial computedtomographies on admission (p>0.05). However, on computed-tomography scans taken after the third day, severe acute-pancreatitis was detected significantly more frequently in the elderly (p<0.05). Additionally, in comparing the disease progression on computed-tomography scans, disease progression was significantly higher in the elderly group (p <0.05). In addition, comorbidity score and mortality rate were found to be significantly higher in the elderly group (p<0.001, p:0042, respectively). Conclusion: In acute pancreatitis, age may have an effect on the severity of the disease. For this reason, multidisciplinary approach and close follow-up with monitoring is crucial in geriatric patients.
The Severity of Acute Pancreatitis According To Modified Balthazar Classification in Patients With Pancreatic Cancer
(Sage Publications Ltd, 2020) Konur, Sevki; Ozkahraman, Adnan; Surmeli, Neslihan; Gunduz, Ihsan; Iliklerden, Umit Haluk; Dertli, Ramazan; Kayar, Yusuf
Objective: Although acute pancreatitis (AP) is a self-limited disease under supportive and medical treatment, it can have life-threatening potential in some patients. Results of studies reporting outcomes of AP-associated pancreatic malignancy are controversial. The aim of this study was to evaluate the severity and prognosis of pancreatic cancer (PC)-related AP by modified Balthazar score. Methods: A total of 354 patients hospitalized and followed up in our clinic between 2013 and 2019 were included in the study. Demographic data of all patients were recorded. The etiology of all cases was determined. According to the etiology, the cases were divided into 2 groups: AP related to pancreatic malignancy and AP due to nonmalignant causes. The patients underwent computed tomography of the abdomen within the first 12 hours of admission and after 3 to 7 days. Patients were evaluated and classified by modified Balthazar classification. Results: Malignancy-related AP was detected in 18 (5.1%) patients. A total of 336 cases (94.9%) were related to nonmalignant causes. There was no statistically significant difference in the severity of AP in both groups at admission and after 3 days (p> 0.05). The changes (regression, progression, or no change) in the disease severity at the first and the subsequent imaging were examined. There was no significant relationship between the 2 groups (p> 0.05). Conclusion: AP may be the clinical manifestation of PC or PC may induce AP in various ways. It was shown that the underlying malignancy did not adversely affect the severity and course of AP.