Browsing by Author "Korkmaz, M.F."

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Problems Encountered in Screening Study With Ultrasound for Early Diagnosis of Developmental Dysplasia of Hip in Eastern Region of Turkey
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Ceylan, M.F.; Güner, S.; Gökalp, M.A.; Kurdoğlu, Z.; Gözen, A.; Korkmaz, M.F.; Tuncer, O.
The aim of this study is to evaluate results of the screening program of the development al dysplasia of the hip (DDH) examined in newborn period. The problems encountered in the applicability of the early screening program were e valuated. By interviewing with the family of 1680 newborns born in our institution or referred, the information was given about the DDH and its risk factors, obtained results were recorded. The families were told to bring their babies for examination and hip ultrasound at the 3rd or 4th week of birth. In addition, all the parents were called by telephone the day prior to their appointments. Five hundred and thirty-six babies (31.3%) were brought to the first appointment. Forty-two hips (3.9%) of the 30 infants (5.6%) were detected as dislocated (Type 2c, D, 3). The 8 of these 30 patients (26.7%) whom the treatment was started were brought for the second control. Asymmetry of thigh folds was positive in the highest rate as the finding of the examination in the infants brought to the appointment. The rate of swaddling at the first appointment was found to be 74.2%. Surprisingly, less than one third of children were brought to ultrasound examination at first control. Similarly, about 3/4 of the parents continued to use swaddling for their babies. For the success of national DDH screening program, additional precautions must be taken to ensure the participation of the families and re lease of the swaddling. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
The Therapeutic Efficacy of Dexpanthenol on Sciatic Nerve Injury in a Rat Model
(Taylor and Francis Ltd., 2020) Korkmaz, M.F.; Parlakpinar, H.; Erdem, M.N.; Ceylan, M.F.; Ediz, L.; Samdanci, E.; Kekilli, E.
Objective: The aim of this study was to evaluate histopathological, functional and bone densitometry examinations of the beneficial effects of dexpanthenol (DEX) on nerve regeneration in a rat model of peripheral nerve crush injury. Methods: Thirty adult Sprague-Dawley rats were divided equally into three groups. A crush injury was simulated in all rats by clamping the right sciatic nerve for one minute. In group 1, one day before the surgical procedure, 500 mg/kg DEX administered via intraperitoneally (ip) was initiated and continued three times in a week during the experiment period as 28 days. In group 2, rats received a dose of 10 mg/kg DEX to investigate possible effects of DEX alone. Group 3 served as the control (sciatic nerve injury) and was not given any drugs. Results: Performance was significantly lower in group 3 compared to the drug treatment groups during the rotarod test (30 rpm and 40 rpm) (p < 0.05). After a while, the rats which were able to remain on the rod was significantly lower in group 3 during the acceleration test (p < 0.05). Hot plate latency test results in group 3 were significantly lower when compared to the other groups (p < 0.05). Conclusion: DEX appears to be useful as a supportive clinical agent for the treatment of pain and nerve damage. © 2020 The Neurosurgical Foundation.