Browsing by Author "Kurdoglu, Z."
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Conference Object Can Monoclonal Antibody Against Laminin Receptor-1 Be a Novel Therapy for Preeclampsia: a Hypothesis for Further Studies on a Rat Model(Wiley-blackwell, 2014) Kurdoglu, M.; Sendag, S.; Kurdoglu, Z.; Wehrend, A.Article Early Prenatal Diagnosis of Conjoined Twins at 7 Weeks and 6 Days' Gestation With Two-Dimensional Doppler Ultrasound: a Case Report(2009) Taner, M.Z.; Kurdoglu, M.; Taskiran, C.; Kurdoglu, Z.; Himmetoglu, O.; Balci, S.This case report presents the prenatal diagnosis of conjoined twins at 7 weeks and 6 days' gestation according to the last menstrual period and 6 weeks and 4 days' gestation according to crown-rump length in a 32-year-old Turkish woman, using two-dimensional Doppler ultrasound. The twins were fused to each other at the thoracic region (thoracopagus). In the light of previous reports of conjoined twins this appears to be one of the earliest prenatally diagnosed cases in the medical literature. © 2009 Taner et al; licensee Cases Network Ltd.Article Eclampsia With Neurological Complications: a Five-Year Experience of a Tertiary Centre(I R O G Canada, inc, 2013) Kurdoglu, Z.; Ay, G.; Sayin, R.; Kurdoglu, M.; Kamaci, M.Purpose: The neurological signs and symptoms in 107 pregnant women with eclampsia in the last five years at the Department of Obstetrics and Gynecology at the Yuzuncu Yil University School of Medicine are presented. Materials and Methods: The medical records of 107 pregnant women with eclampsia in the Clinic of Obstetrics and Gynecology at the Yuzuncu Yil University consulted with neurology clinic from September 2005 to December 2010, were evaluated. Results: The most common symptoms of the patients were seizure, headache, and seeing spots of light. Although neurologic examination was normal in 81 patients, 26 had pathological signs. The most common neurologic pathologic signs determined were alterations in consciousness. Conclusion: In eclamptic patients, brain scanning might reveal pathological results in spite of normal neurological examination. With neurological examination and brain scanning, it may be possible to diagnose and treat severe complications that may otherwise result in maternal mortality.Article Evaluation of Maternal Mortality Ratio and Causes in a University Hospital in Eastern Turkey(S.O.G. CANADA Inc., 2015) Kurdoglu, Z.; Dalbudak, T.; Kurdoglu, M.; Yildizhan, R.; Sahin, H.G.Aim: To investigate the maternal mortality ratio (MMR) and causes of maternal death in order to decrease these deaths. Materials and Methods: The number of live births, maternal deaths, and the causes of deaths in Yuzuncu Yil University were recorded between 2004 and 2013. Results: The MMR was 268 per 100,000. Forty-nine maternal deaths were examined in terms of cause. The most frequent cause of death is eclampsia (33%) and associated intracerebral complications. The antenatal follow-up rate was 23.3%. The majority of patients had low income (92.3%), 72.2% were from rural areas, and 95.5% were illiterate. Conclusion: The high MMR may arise from the high incidence of pregnancy complications in eastern Turkey, the rareness of antenatal follow-ups, and the present hospital being a referral hospital. The most frequent cause of maternal mortality is eclampsia and associated complications, followed by bleeding.Article Evaluation of the Relationship Between Endogenous Gonadotropins and Female Sexual Function and Psychological Status in Predialysis and Hemodialysis Patients(C I C-edizioni int Srl, 2012) Kurdoglu, Z.; Soyoral, Usul Y.; Tasdemir, M.; Kurdoglu, M.Article Evisceration of the Fallopian Tube at the Site of a Pezzer Drain After Caesarean Section: Is Conservative Management Possible(Taylor & Francis inc, 2015) Kurdoglu, Z.; Elci, E.; Cetin, O.; Kurdoglu, M.Conference Object Is There a Role of Laminin Receptor-1 in Brucella-Related Abortions(Wiley-blackwell, 2015) Kurdoglu, M.; Sendag, S.; Kurdoglu, Z.Article Management of Haemangiopericytoma Located in the Spinal Cord Diagnosed During Pregnancy(Taylor & Francis inc, 2015) Kurdoglu, Z.; Cetin, O.; Bulut, G.; Erten, R.; Gulsen, I.; Sahin, H. GulerArticle Oxidative Status and Its Relation With Insulin Resistance in Young Non-Obese Women With Polycystic Ovary Syndrome(Springer, 2012) Kurdoglu, Z.; Ozkol, H.; Tuluce, Y.; Koyuncu, I.Background: Oxidative stress may play a role in the pathophysiology of polycystic ovary syndrome (PCOS). Insulin resistance (IR) also can be found in young non-obese women with PCOS. Hyperglycemia may increase reactive oxygen species production and decrease antioxidant levels. Aim: To investigate oxidative status and its relation with IR in young non-obese patients with PCOS. Material/subjects and methods: Thirty-one patients with hyperinsulinemic (no.=13) and normoinsulinemic (no.=18) PCOS and 29 healthy controls were included in this study. Serum levels of glucose, insulin, gonadotropins, total testosterone, DHEAS, SHBG, 2-h plasma glucose on oral glucose tolerance test, malondialdehyde (MDA), protein carbonyl (PC), reduced glutathione (GSH), beta carotene, vitamin A, C, E and the enzyme activities of catalase and glutathione S-transferase (GST), IR [by homeostasis model assessment (HOMA)-IR], and beta cell function [by HOMA-B] were assessed. Results: Serum glucose, insulin, total testosterone, DHEAS. HOMA-IR levels, and LH/FSH ratios were higher in young non-obese women with PCOS. Serum MDA and PC levels were also higher but GSH, vitamin C and E levels, and GST enzyme activity were lower in these women than in healthy controls, independently of the status of IR (p<0.05). Conclusions: Oxidative stress characterized by increased oxidants and decreased antioxidant levels which are independent of IR may be involved in the pathogenesis of PCOS in young non-obese women. (J. Endocrinol. Invest. 35: 317-321, 2012) (C)2012, Editrice KurtisConference Object Posterior Reversible Encephalopathy Syndrome in Eclamptic Patients: Five Years Experience of a Tertiary Center(Wiley-blackwell, 2014) Kurdoglu, Z.; Sayin, R.; Cetin, O.; Dirik, D.; Karaagac, N.Article Serum Myeloperoxidase and Adenosine Deaminase Activities in Polycystic Ovary Syndrome(2012) Kurdoglu, Z.; Ozkol, H.; Kurdoglu, M.Objective: To evaluate serum myeloperoxidase (MPO) and adenosine deaminase activities and to investigate whether there was a correlation between these and sex hormones, and lipids in polycystic ovary syndrome. Design and methods: Forty-five women with polycystic ovary syndrome and 40 healthy controls were included in this study. Leukocyte counts, serum MPO and adenosine deaminase activities, and high-sensitive C-reactive protein (hs-CRP), sex hormone and lipid levels were assessed. Results: Leukocyte counts and serum MPO activities were higher (p<0.01 and p<0.05, respectively) and there was a significant correlation between serum adenosine deaminase and hs-CRP level in women with polycystic ovary syndrome (r=0.853, p<0.01). Serum MPO and adenosine deaminase levels did not correlate with sex hormones or lipid profiles in these patients. Conclusion: Polycystic ovary syndrome may involve an inflammatory process by increasing serum MPO activity independent of sex hormones, body mass index and lipid profiles. © 2012 Informa UK, Ltd.Article Serum Trace Elements and Heavy Metals in Polycystic Ovary Syndrome(Sage Publications Ltd, 2012) Kurdoglu, Z.; Kurdoglu, M.; Demir, H.; Sahin, H. G.Objective: We aimed to investigate the serum levels of essential trace elements copper (Cu), zinc (Zn), manganese (Mn), magnesium (Mg) and heavy metals cadmium (Cd), cobalt (Co) and lead (Pb) in the patients with polycystic ovary syndrome (PCOS). Methods: A total of 65 (35 patients with PCOS and 30 healthy controls) women were included in the study. Serum Cu, Zn, Mn, Pb, Mg, Co and Cd levels were analyzed using atomic absorption spectrophotometric method. Results: Serum Cu and Zn levels were significantly higher, but Mn and Pb levels were lower in patients with PCOS compared with the healthy participants (p<0.01). There was no difference between patients with PCOS and the controls with respect to the serum levels of Mg, Co and Cd. Conclusions: This is the first study investigating serum Cu, Zn, Mn, Pb, Co, Mg and Cd levels in the patients with PCOS. The serum levels of trace elements and heavy metals might change in patients with PCOS. The findings in this study should be investigated with further trials in order to obtain new insights into PCOS.Article Spontaneous Iliopsoas Haematoma During Heparin Anticoagulation: Cause of Fetal Loss(informa Healthcare, 2008) Kurdoglu, M.; Onan, M. Anil; Turp, A.; Kurdoglu, Z.Article An Unusual Cause of Dyspnea in a Pregnant Woman: Supraglottic Hemangioma(Medquest Communications LLC, 2014) Kurdoglu, Z.; Kurdoglu, M.; Cankaya, H.Dyspnea is a common complaint among pregnant women; upper airway obstruction is a rare cause of it. We report a case of supraglottic hemangioma in a 20-year-old pregnant woman who presented with increasing dyspnea and hoarseness at 40 weeks of gestation. She gave birth to a healthy 3,100-g girl by caesarean delivery under epidural anesthesia. She was able to breathe easily during the postpartum period. This case represents a rare instance of dyspnea caused by a supraglottic hemangioma in a pregnant woman.