Browsing by Author "Melek, M."

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An Analysis of Corrosive Substance Ingestion of Children in Eastern Turkey
(2008) Melek, M.; Edirne, Y.; Çobanoǧlu, U.; Ceylan, A.; Can, M.
In this study, we aimed at describing corrosive substance ingestion and related problems in Eastern Turkey. This type of injury is still a serious problem to be given a careful attention in our country like the other developing countries. The charts of children managed in our hospital with corrosive substance ingestion in the period of 1996- 2008 were evaluated retrospectively. Gender, age, ingested substance and the volume, symptoms, morbidity of caustic injury were considered in the analysis of the charts. We had 40 male and 35 female cases. 82% of children were under 5 years old. Mean age was determined as approximately 3.5 years. Bleach was the most common corrosive substance received and it was followed by hydrochloric acid. The volume of the ingested substance varied between 1-100 ml. The volume could not be estimated in 36 children. It was determined that 54% of ingested corrosive substance was in its original package. Twenty-five cases ingested the substance from food or drink containers that was stored somewhere in the kitchen. Five children had developed esophageal strictures. They were included in esophageal dilatation program. In our country the morbidity of caustic esophageal burn is still a problem that should be involved. Attention to the storage conditions and secured bottle cap seems to be the easiest and simplest way to prevent corrosive substance ingestion.
Management and Treatment of Foreign Bodies Ingestion in Childhood
(2011) Melek, M.; Cobanoglu, U.; Bilici, S.; Beger, B.; Kizilyidiz, B.S.; Melek, Y.
Ingestion of foreign bodies (FBs) is a significant problem that causes morbidity and mortality in childhood. The aim of this retrospective study was to report our experience of foreign body ingestion in pediatric patients. The medical records of 165 patients who were hospitalized for foreign body (FB) ingestion in pediatric and chest surgery departments between 2005 and January 2010 were evaluated retrospectively. X-ray films and abdominal ultrasound scan were used for the diagnostic approach of the patients. The common complaints were odynophagia-dysphagia (n=107), hypersalivation (n=81), cough (n=21), vomitting (n=20) and asymptomatic in 34 patients. Radiological examinations showed that FB was located in the esophagus in 81.2% (n=134) of the patients, in the stomach of 6.74% (n=11) patients, in the intestinal segments in 10.4% (n=17), in the rectum in 1.21% (n=2) and in the liver parenchyma 0.6% (n=1) patients. Endoscopic examination performed in 134 (81.2%), FB proceeded uneventfully in 23 (13.9%) in follow up period and 8 (4.8%) patients underwent surgery. The type of ingested FB varied widely. The coins (n=54, 32.7%) and pieces of plastic toys (n=29, 17.5%) were the most frequently ingested FBs. Foreign body ingestion is a major problem in childhood. Management depends on carefully and close follow up for complications and favorable treatment choice.
Mean Platelet Volume in Diagnosis of Acute Appendicitis in Children
(Makerere Univ, Fac Med, 2011) Bilici, S.; Sekmenli, T.; Goksu, M.; Melek, M.; Avci, V
Background: The clinical diagnosis of acute appendicitis (AA) in children is still problematic in status. Objectives: To investigate the diagnostic value of mean platelet volume (MPV) in acute AA at childhood. Methods: One hundred patients diagnosed as AA patients and 100 healthy individuals. Laboratory tests were studied in the hematology laboratory of the hospital. Results: The MPV was found to be lower than normal in 48 cases in the AA group, and it was normal or higher than normal in 52 cases. In the control group, while MPV was found to be lower than normal in 13 cases, it was normal or higher than normal in 87 cases. The MPV was significantly lower in the AA group compared to the control group (p<0.001). Conclusion: Our study indicated that MPV significantly decreased in pediatric AA patients. Hence, we believe that taking the MPV decrease into consideration along with the White Blood Cell Count elevation would be beneficial in patients with suspicion of AA.
A New Enema for Treatment of Intussusception With Hydrostatic Reduction: Olive Oil
(Wolters Kluwer Medknow Publications, 2019) Beger, B.; Duz, E.; Kizilyildiz, B.; Akdeniz, H.; Melek, M.; Agengin, K.; Sonmez, B.
Objectives: Intussusception is routinely treated using ultrasound-guided hydrostatic reduction (USGHR) with normal saline in our paediatric surgery department. With this study, olive oil was added to normal saline in ultrasound-guided reduction of intussusception. Materials and Methods: Forty patients who were diagnosed and treated for intussusception in Van Yuzuncu Yil University Faculty of Medicine Pediatric Surgery Department from March 2017 to May 2017 were included in the study. During this retrospective study, randomly chosen 20 patients that treated with USGHR using normal saline were marked as Group 1. Moreover, 20 patients that treated with USGHR using a mixture of olive oil and saline (10% olive oil 90% normal saline) were marked as Group 2. Patients' age, gender, symptoms, treatment techniques, complications and hospitalisation periods were retrospectively noted. Results: Forty patients were included in the study. In Group 1, 14 patients were treated in the first session, 4 patients were treated in the second session and 2 patients required laparotomy. Mean reduction time in this group was 15 min mean fluid volume used in each reduction was 80 ml/kg and mean hospitalisation period was 38 h. In Group 2, 19 patients were treated in the first session, and only 1 patient required a second session. Mean reduction time was 12 min, used fluid volume was 58 ml/kg for each reduction and hospitalisation period was 24 h. Conclusion: The average volume of fluid used for reduction, average reduction time, numbers of recurrent reductions and hospitalisation were less when a mixture of olive oil and normal saline were used in comparison with when normal saline was used alone to reduction the intussusception under ultrasound guidance. Using olive oil mixed with normal saline as a new enema fluid is likely to increase the success rate of ultrasound-guided reduction of intussusception. © 2019 Wolters Kluwer Medknow Publications. All rights reserved.
Ovarian Artery Injury as a Peritoneal Dialysis Complication: Case Report
(2009) Melek, M.; Edirne, Y.; Beger, B.; Çetin, M.
Patients treated with peritoneal dialysis are prone to many complications like peritonitis, catheter exit-site infection, catheter disfunction, insufficient clearance and ultra-filtration. Although hemoperitoneum is described as a benign complication, one should be cautious against it because of its life-threatening severe form seen in approximately 20 % of patients. There are several studies reporting intra-peritoneal hemorrhage during the procedure but a specific localization of the hemorrhage is not mentioned. We present here a case of 2 months old female infant who died due to intra-abdominal hemorrhage caused by ovarian artery injury on the 4th day after peritoneal dialysis was performed. Catheters made of hard material can cause hemorrhage. Fixation of these catheters is vital.
Oxidative Stress and Antioxidant Enzyme Activities in Newborns With Oesophageal Atresia and Their Mothers
(Sage Publications Ltd, 2012) Melek, M.; Demir, H.; Bilici, S.; Beger, B.; Cobanoglu, U.; Meral, I.; Ozmen, E.
OBJECTIVE: To measure the oxidant/antioxidant status of newborn babies with oesophageal atresia and their mothers, compared with healthy control subjects. METHODS: This case control study included 40 participants: 10 newborns with oesophageal atresia and their mothers, and 10 healthy newborns and their mothers. Whole blood malondialdehyde (MDA) levels and the activities of antioxidant enzymes (catalase, carbonic anhydrase [CA], glucose-6-phosphate dehydrogenase [G-6-PD], and superoxide dismutase [SOD]) were measured. RESULTS: MDA levels and CA activity were significantly higher, and catalase, SOD and G-6-PD activities were significantly lower, in newborns with oesophageal atresia and their mothers than in healthy newborns and their mothers. Although CA activity was similar between the newborns and mothers in the patient group, it was significantly lower in newborns than in mothers in the healthy group. CONCLUSIONS: Increased lipid peroxidation might play an important role in the pathogenesis of oesophageal atresia. Impairment of the free radical/antioxidant balance may lead to increased free radical and decreased antioxidant levels in oesophageal atresia.