Browsing by Author "Mermi̇t, Buket"

Now showing 1 - 5 of 5

Aklınızda Bulunsun: Klomifen Sitrat Kullanımına Bağlı Pulmoner Emboli
(2021) Mermi̇t, Buket; Sunnetcioglu, Aysel; Yıldız, Hanifi
Yirmi sekiz yaşındaki bayan hasta bir gündür devam eden göğüs ağrısı nedeniyle başvurdu. Ovulatuar disfonksiyonun klomifen sitrat ile tedavisi 20 gün önce başlatılmıştı. Hastanın nabız hızı 120 vuru / dakika ve kan basıncı 100/60 mmHg idi. Elektrokar- diyografide sinüs taşikardisi saptandı. Arteriyel kan gazı testi sonucunda hem hipoksi hem de hipokapni tespit edildi. D-dimer seviyesi 5.2 μg / ml olarak ölçüldü. Bilgisayarlı tomografi anjiyografisinde sağ alt lob pulmoner arter ve alt lob segment dallarında pulmoner emboli ile uyumlu dolum defektleri görül- dü. Transtorasik ekokardiyografide ejeksiyon fraksi- yonu %65 idi ve trombüs izlenmedi. Hastaya klomifen sitrat kullanımına bağlı pulmoner emboli tanısı kon- du. Bemiparin sodyum ile antikoagülan tedavi baş- landı ve hasta taburcu edildi. Klomifen sitrat kullanı- mına bağlı akut pulmoner emboli, nadir görülen ancak karşılaşıldığında yaşamı tehdit eden bir komp- likasyon olabilir. Doktorlar olası pulmoner emboli riskinin farkında olmalıdır.
Batın Cerrahi Sonrası Radyolojik Bulgu Gösteren Akciğer Komplikasyonlarının Değerlendirilmesi
(2021) Ekin, Selami; Sunnetcioglu, Aysel; Mermi̇t, Buket; Yuzkat, Nureddın
GİRİŞ ve AMAÇ: Cerrahi girişimler ve uygulanan anestezi sonrasında meydana gelen patofizyolojik değişiklikler akciğer komplikasyonlarının gelişimini kolaylaştırmaktadır. Bu çalışmada batın cerahisi sonrası radyolojik bulgu gösteren akciğer komplikasyonlarının değerlendirilmesi amaçlandı. YÖNTEM ve GEREÇLER: Genel enestezi altında batın cerahisi yapılan 619 hastadan istenen göğüs hastalıkları konsültasyonları retrospektif olarak incelendi. Radyolojik bulgu saptanan hastalar çalışmaya alındı. BULGULAR: Postoperatif göğüs hastalıkları konsültasyonu istenen hastaların %20,7’sinde radyolojik bulgu tespit edildi. Hastaların yaş ortalaması 57.28±11.2 olarak saptandı. Değerlendirilen 128 hastanın, 81 (63.2%) üst batın, 47’ne (36.7%) alt batın cerahisi yapılmıştı. Üst batın cerahi yapılan hastaların 51’i (62.9%) 60 yaş üzerindeydi. En sık akciğer komplikasyonları plevral effüsion (32.8%), pnömoni (26.5%), atelektazi (17.9%) idi. Üst batın cerahisinde ateletazi(69.5%) ve plevral effüzyon(66%) daha fazla iken alt batın cerrahisinde pnömoni (76%) daha sıktı. TARTIŞMA ve SONUÇ: Plevral efüzyon, pnömoni ve atelektazi, batın cerahisi sonrası radyolojik bulgu veren en yaygın akciğer komplikasyonlarıydı. Özellikle üst batın cearahisi sonrası ateletazi ve plevral efüzyon, alt batın cerahisi sonrası ise pnömoni daha sık görülmesine rağmen bu komplikasyonların gelişiminde risk faktörleri arasında önemli bir fark yoktu.
Could a New Measurement, a New Body Shape Index, Replace Bmi in Detecting Obesity and Predict the Presence of Obesity and Depression in Asthma Control
(2022) Ekin, Selami; Mermi̇t, Buket; Gunbatar, Hulya; Yıldız, Hanifi; Sunnetcioglu, Aysel
Obesity is common in asthma. Depression is thought to be one of the risk factors that increase obesity. It is known that depression has an effect on poor asthma control. Body Mass Index (BMI) is mostly used to define obesity. In recent years, however, the ‘A Body Shape Index’ (ABSI) based on waist circumference (WC) measurement has been developed and the higher ABSI corresponds to a more central body volume concentration. Our aim was to examine the effect of obesity and depression on asthma control in a way that questions the usability of ABSI, which is new in abdominal obesity measurement. A total of 99 asthmatic patients aged between 18-80 years who were followed up in Chest Diseases outpatient clinics were included in the study. Demographic and medical history of the patients were recorded. Waist circumference /BMI2/3 X Length(m) 2/3 was calculated for ABSI measurement. Beck Depression Scale (BDS) and Asthma Control Test (ACT) were applied. Pulmonary Function Test was applied to all patients by the same trained person. Obese and morbidly obese patients had poor asthma control. We found that the presence of depression caused poor asthma control in all BMI groups. The poorly controlled asthma group and the obese and morbidly obese patients had higher depression scores. BMI and waist circumference were higher in the poorly controlled asthma group (p=0.002, 0.033 respectively). However, there was no significant difference between the asthma groups in terms of ABSI (p=0.529). The findings of this study indicate that depressive symptoms, increased BMI and WC were significantly associated with poor asthma control. But ABSI is no superior to BMI in detecting asthma control and depressive mood. However, we should prompt our patients to treatment and exercise, especially for abdominal obesity. We should recommend that asthma patients with depression consult a psychiatrist. In this way, we can control our asthma patients more effectively by minimizing the existing risks.
Evaluation of Platelet Distribution Width(PDW) and Mean Platelet Volume(MPV) in Patients With Obstructive Sleep Apnea Syndrome(OSAS): A Retrospective Clinical Study
(Yuzuncu Yil Universitesi Tip Fakultesi, 2024) Mermi̇t, Buket
This study aimed to evaluate the association between PDW and MPV with Obstructive Sleep Apnea Syndrome (OSAS). The study’s design is a retrospective evaluation of OSAS patients admitted to our pulmonology department between January 2022 and June 2024. The data and clinical-laboratory parameters of patients diagnosed with polysomnography were evaluated. The PDW and MPV measurements were retrieved from the complete blood counts’ of the patients. OSAS patients were divided into three groups according to the Apnea-hypopnea Index(AHI) score as mild, moderate and severe OSAS. Healthy subjects with no known chronic disease admitted to our outpatient clinic were enrolled as control group. In total, 140 patients with OSAS and 120 healthy subjects as control group were included in the study. The OSAS groups consisted of as 60 mild, 45 moderate, and 35 severe. The mean age of OSAS group and control group were as 51.8 12 and 47.611, respectively which was not statistically significant. There was statist ically significant difference between OSAS and control group with respect to the BMI(31.85.0 vs 26.44.2, p:0.01). The male/female patients were 96/44 in OSAS and 86/34 in control group which was not statistically different (p:0.04). The mean PDW and MPW were 18.82.5 and 10.71.2 in OSAS group. The mean PDW and MPV were 14.61.7 and 7.82.4 in control group. There was statistically significant difference between OSAS and control group with respect to mean PDW and MPV values (p:0.02 and p:0.01). The subgroup analysis showed that MPV increased statistically significant as OSAS severity got impaired. This study showed that increased PDW and MPV was associated with OSAS and also the activation of platelets has potential effect on the severity of OSAS.
Is It in Our Genes That We're Going to Have Pulmonary Embolism
(Yuzuncu Yil Universitesi Tip Fakultesi, 2024) Mermi̇t, Buket; Üney, İbrahim Halil; Gunbatar, Hulya; Yıldız, Hanifi; Ekin, Selami; Sunnetcioglu, Aysel; Arisoy, Ahmet
Pulmonary thromboembolism is a disease with high mortality and morbidity, which can be recurrent, difficult to diagnose, yet preventable and treatable. In this study, our aim was to evaluate comorbidities, risk factors, laboratory results, and clinical scoring in patients diagnosed with pulmonary embolism. Our primary goal was to detect genetic mutations in cases of pulmonary embolism with acquired risk factors. Our study is a prospective study that includes clinical information, laboratory tests, Wells scoring, admission, and the prospective history of 60 patients with no previous history of venous thromboembolism (VTE) and no history of anticoagulation use. These patients were admitted to the chest diseases outpatient clinic, emergency department, or hospitalized for another reason and diagnosed with pulmonary thromboembolism. The mean age of the patients was 59.9 ± 18.7 years. The most common presenting complaints were shortness of b reath and sharp chest pain. Nearly half of the patients had at least one comorbid disease. There was at least one genetic/congenital risk factor in all cases, and at least two risk factors were present in more than half of the cases. The most common mutations were plasminogen activator inhibitor type 1 (PAI -1) and Methylenetetrahydrofolate Reductase (MTHFR) heterozygote mutations. Pulmonary embolism continues to be a more prevalent disease with increasing age and associated risk factors. Since there is at least one acquired risk factor in all of our cases, we believe that almost every patient may have an acquired risk factor if the history is thoroughly investigated. We also believe that genetic or thrombophilic conditions may be detected in almost all cases diagnosed with pulmonary embolism. It has been concluded that immobilization and obesity are the most common preventable risk factors associated with VTE.