Browsing by Author "Mert, N."

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Ascorbic Acid and Heat Stress in Laying Hens
(Medwell Journals, 2014) Mert, H.; Mert, N.; Irak, K.
There are so many stressors, like heat, effects the egg production in laying hens. Experiment was conducted in a poultry farm inBursa. 1730Hy-Line W77 layer aged 40 weeks assigned to caging unit were used as research materials. Hens were divided into six groups and had different amount of ascorbate supplementation; 0, 50, 100, 150, 200 and 250 mg kg-1 feed. Egg production and body weighted were recorded. As result the best ascorbate supplementation to decrease heat stress for this experiment was 100 mg kg-1 feed.© Medwell Journals, 2014.
Biochemical Parameters and Histopathological Findings in the Forced Molt Laying Hens
(Facta-fundacio Arnco Ciencia Tecnologia Avicolas, 2016) Mert, N.; Yildirim, B. A.
The aim of this study was to evaluate the effects of forced molting using biochemical parameters and histopathological findings in laying hens. 36 Hyline W36 strain laying hens, 90 weeks old were chosen for this research. Eight of these chickens were randomly selected and placed in a cage as the control group before the molting program began. All the others 28 chickens were used for the forced molting program. Eight laying hens were slaughtered at the end of the molting program named as molting group. The remaining 20 hens were fed for 37 days, weighted and slaughtered when they reached the maximum egg production (80%) as postmolting group. Then, blood was analyzed for malondialdehyde, glutathione, catalase, glucose, calcium, phosphorus, albumin, globulin, total protein, triiodothyronine, thyroxine and Vitamin C. The malondialdehyde and glutathione levels of the thyroid and liver tissues were also analyzed along with an examination of the histopathological changes of the liver, ovarium and thyroid glands; and live body, liver, ovarium, thyroid weights and thyroid lengths. In conclusion, it was found that forced molting produces stress and notable side effects in hens, like the oxidant and antioxidant status of the organs, tissue weights and sizes, hormon profiles, blood biochemical and histopathological parameter changes. The activities of thyroid malondialdehyde (p<0.05), liver glutathione (p<0.01), plasma catalase (p<0.001) were significantly decreased in molting group compared to control values, while liver malondialdehyde levels were significantly increased (p<0.001) and thyroid glutathione levels had nonsignificant effect. These levels in molting hens were the first study for veterinary science.
Effect of Couch Grass (Agropyrum Repens) on Gentamicin-Induced Nephrotoxicity
(Yuzuncu Yil Universitesi Tip Fakultesi, 2022) Çibuk, S.; Yurtkulu, B.; Mert, N.; Mert, H.
Couch grass is used to clean the urinary tract during infections due to its diuretic and antimicrobial effects. The aim of this study was to investigate the possible protective or therapeutic effects of couch grass on gentamycin-induced nephrotoxicity in rats. Four groups of 10 rats were formed in the study. First group, Control: Rats were fed with standard rat feed and water. Second group (couch grass): 3 gr/L couch grass was added to the drinking water of rats for 7 days. The third group (gentamicin): Gentamicin 80 mg/ kg/ day/ i.p. was given for 7 days. The fourth group (gentamicin + couch grass): Gentamicin 80 mg/kg/day/ i.p. and 3 g/L couch grass was added to drinking water for 7 days. One week after the experimental application, blood samples were taken and serum was separated. Albumin, BUN, creatinine, urea, GGT, ALP, Na, Cl and K levels were determined in autoanalyzer. Cystatin C was measured by ELISA. Serum BUN, creatinine, urea, Na, K levels were highest in the gentamicin group. Na, K and cystatin C levels differences between groups were not statistically significant. The increase in BUN, urea and creatinine after gentamicin administration was statistically significant (p<0.05). The use of gentamycin and couch grass caused BUN, urea and creatinine levels to decrease. The difference between the groups was found to be statistically significant (p<0.05). The administration of gentamycin and couch grass decreased cystatin C levels, statistical significance was found between the groups (p<0.05). No statistically significant difference was found between the groups in albumin, Cl, GGT, ALP levels (p>0.05). As result, positive changes in serum parameters of gentamycin-induced nephrotoxicity when couch grass were given, showed that couch grass had a kidney protective effect and decreased nephrotoxic damage. © 2022, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Evaluation of Levels of Some Tumor Markers, Acute Phase Proteins, Sialic Acid and Lipid Bound Sialic Acid Before and After Treatment in Stomach Cancer Patients
(Blackwell Publishing, 2008) Cebi, A.; Mert, H.; Mert, N.
Serum Concentration of Copper, Zinc, Iron, and Cobalt and the Copper/Zinc Ratio in Horses With Equine Herpesvirus-1 (Biological Trace Element Research Doi: 10.1007/S12011-007-0023-y)
(2008) Yörük, I.; Deger, Y.; Mert, H.; Mert, N.
Serum Total and Lipid-Bound Sialic Acid Concentrations in Sheep With Natural Babesiosis
(veterinarni A Farmaceuticka Univerzita Brno, 2007) Deger, Y.; Mert, H.; Dede, S.; Yur, F.; Mert, N.
The aim of this study was to determine the serum concentrations of total and lipid-bound sialic acid in sheep naturally infected with Babesia ovis before and after treatment. Thirty diseased sheep and ten control animals were used. Babesia infection was confirmed with Giemsa's staining of blood smears. Compared to the control animals (1.351 +/- 0.100 mmol center dot l(-1); 0.385 +/- 0.001 mmol center dot l(-1)), a marked increase of serum total and lipid bound sialic acid concentrations (1.929 +/- 0.101 mmol center dot l(-1); 0.479 +/- 0.004 mmol center dot l(-1), respectively) was obtained in infected sheep (p < 0.05). One week after treatment, serum total and lipid bound sialic acid concentrations significantly decreased (1.554 +/- 0.005 mmol center dot l(-1); 0.411 +/- 0.02 mmol center dot l(-1), respectively) (P < 0.05). Despite this decline, total and lipid bound sialic acid concentrations of treated animals were still significantly increased in sera compared to the control animals (p < 0.05). When the infected animals were treated with an antiparasitic drug (diminazene aceturate), the serum total and lipid bound sialic acid levels had a tendency to decrease to the normal ranges. It can be concluded that Babesia ovis infection induced marked and persistent elevations of serum total and lipid-bound sialic acid concentrations, suggesting that these indicators would indirectly promote the invasion and presence of the parasite in the host.