Browsing by Author "Metin, A."

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Oesophageal Involvement During Attacks in Pemphigus Vulgaris Patients
(Wiley, 2006) Calka, O.; Akdeniz, N.; Tuncer, I.; Metin, A.; Cesur, R. S.
Pemphigus vulgaris (PV) is a rare autoimmune bullous skin disorder characterized by frequent involvement of the mucous membranes, usually beginning at the mouth. To investigate the oesophageal involvement in patients with PV and to explore the primary relationship of the disease with symptoms such as dysphagia, odynophagia and retrosternal burning. Oesophageal involvement was investigated by upper gastrointestinal endoscopy and biopsy during the early phase of the attacks in 26 patients with PV (12 men, 14 women, age range 24-63 years). Histopathological examination and direct immunofluorescence of the oesophageal biopsy specimens revealed pemphigus involvement in 12 of 26 patients (46.15%). The oesophagus is an important predilection zone for PV, thus care must be taken to detect these lesions at an early stage.
Otorhinolaryngological Aspects of Xeroderma Pigmentosum
(1999) Kutluhan, A.; Bekerecioglu, M.; Güney, E.; Metin, A.
Objective: to evaluate the probable presence of otorhinolaryngological pathology accompanied by head and neck region skin findings in patients with Xeroderma pigmentosum. Methods: a total of 19 patients with Xeroderma pigmentosum were investigated for otorhinolaryngological findings. The patients gave their anamnesis and underwent physical examination, audiological tests and endoscopic examination. Results: various malignancies developed in 14 patients on the sun-exposed areas of the head and neck region. Multiple malignancies were found in six of them. There was no other pathological condition secondary to this rare clinical entity. Conclusion: Xeroderma pigmentosum causes skin lesions. Some otolaryngological findings such as rhinitis, sinusitis etc. were thought to be coincidental. Copyright (C) 1999 Elsevier Science Ireland Ltd.
Upper Esophageal Stenosis in a Case With Rothmund-Thomson Syndrome
(2001) Tuncer, I.; Metin, A.; Uǧraş, S.; Uygan, I.
Rothmund-Thomson Syndrome is an autosomal recessive disease that may be accompained by development abnormalities. Etiology of the disease has been postulated to DNA repair deficiency and intestinal anomaly has been very rarely. The case of RTS. admitted with dysphagia due to esophagus stenosis and his complaints disappeared completely after esophagus dilatation, was discussed ill the light of literature aknowledgement.