Browsing by Author "Milanlioglu, A."
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Article The Association Between Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels and Clinical Prognosis in Patients With Ischemic Stroke(Turkish Society of Cerebrovascular Diseases, 2015) Yasar, H.; Tombul, T.; Milanlioglu, A.Objective: Recent studies report that the insulin-like growth factor system may be involved in stroke pathogenesis, and is reported to increase myelination, maturation, cell proliferation and neuronal sprouting of the central nervous system.The aim of the present study is to demonstrate the role of insulin-like growth factor system in ischemic stroke pathogenesis and its association with the prognosis by investigating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 levels in patients diagnosed with acute ischemic stroke. MATERIAL and METHODS: Sixty-eight patients and 20 healthy individuals were included to this study. Clinical evaluation of the patients was performed according to National Institute of Health Stroke Scale and functional outcomes were graded according to Modified Rankin Scale. Bamford classification was used for the clinical classification of ischemic strokes, and the TOAST system for etiological classification. Each patient's levels of insulin-like growth factor-1 and insulin-like growth factor binding protein-3 were measured on the first, fifth and thirtieth day of ischemic stroke. RESULTS: Only the levels of insulin-like growth factor binding protein-3 on the day of 5 were significantly decreased compared to the control group. The decrease in IGF-1 values was associated with an increased risk of death and was accompanied by clinical worsening and decreased functionality. CONCLUSION: It has been concluded that the levels of investigating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 may affect mortality risk, clinical condition and functionality outcomes in patients presenting with ischemic stroke, and further studies are needed for the investigation of different effects of insulin-like growth factor- 1 in future.Article Clinical Subtypes, Seasonality, and Short-Term Prognosis of Guillain-Barre Syndrome in an Eastern City of Turkey(Asean Neurological Assoc, 2022) Kiraz, M.; Yilgor, A.; Milanlioglu, A.; Cilingir, V; Cagac, A.; Ozkan, S.Background & Objective: This study aimed to analyze the frequency Guillain-Barre syndrome (GBS) subtypes and their relationship with clinical characteristics, seasonal variations and early prognosis in Van City, Turkey. Methods: Patients with GBS who were admitted between January 2007 and December 2017 and diagnosed with acute inflammatory demyelinating neuropathy (AIDP), acute motor axonal neuropathy (AMAN) or acute motor sensory axonal neuropathy (AMSAN) were reviewed. Demographics, season of clinical onset, history and type of preceding infection, the Hughes Disability Score (HDS) at admission and discharge were recorded. Results: Of a total 100 patients, 51% was diagnosed with AIDP, 25% with AMAN and the remaining 24% with AMSAN subtype. The most common seasonal onset was during the spring (34%), followed by the fall (30%). The history of gastroenteritis (GE) was present in 26% of the patients and these patients were more likely to have AMAN and AMSAN subtypes. HDS on admission and at discharge were significantly higher in patients with AMAN and AMSAN compared to those with AIDP (p=0.003 and p<0.001, respectively). The most important predictor of poor outcome at discharge was HDS on admission explaining between 50% and 80% of the total variance.Conclusion: There is a high prevalence of AMAN and AMSAN subtypes in Eastern region of Turkey. The history of GE, which is also commonly found in patients with GBS in this region, is more likely detected in patients with AMAN and AMSAN subtypes. Finally, clinical severity on admission is the most important contributor to clinical outcome at discharge.Conference Object Coping Strategies and Profile of Mood States in Patients With Multiple Sclerosis(Sage Publications Ltd, 2013) Milanlioglu, A.; Ozdemir, P. Guzel; Cilingir, V.; Aydin, M. N.; Tombul, T.Article Eeg Under Sleep-Deprived Conditions: Its Usefulness in Psychiatry: Two Case Examples(American Psychiatric Publishing Inc., 2014) Özdemir, O.; Aydin, A.; Milanlioglu, A.; Yilmaz, E.Epilepsy is a brain disorder characterized by recurrent and unpredictable seizures. It is associated with an increased risk of developing mental disorders. Electroencephalography (EEG) is the most important diagnostic tool for this disease; however, a normal EEG cannot exclude the diagnosis of epileptic seizures, so EEG performed under sleep deprivation was performed in two case examples treated in the psychiatry clinic, in order to prove that sleep deprivation may increase epileptiform discharges. © 2014 by the American Psychiatric Association.Article Magnetic Resonance Imaging Findings in Cerebral Venous Thrombosis Due To Behcet's Disease and the Importance of Susceptibility-Weighted Imaging: Case Report(Turkish Society of Cerebrovascular Diseases, 2015) Bulut, M.D.; Yavuz, A.; Milanlioglu, A.; Bora, A.; Gülsen, I.Cerebral venous thrombosis (CVT) is an uncommon disorder that can lead to an unfavorable prognosis and even be fatal in some cases. CVT is seen mainly in females, especially those between the ages of 20 and 35 years. The disorder has many etiologic factors. This report presents the case of a 34-year-old male patient with Behçet's disease admitted with complaints of headache and vomiting. The major venous vascular structures that were visible in cranial magnetic resonance imaging (MRI) and MR venography were found to be filled with thrombosis. The patient's susceptibilityweighted imaging (SWI) revealed marked hypointensities consistent with thrombosis in the transverse sinus, sigmoid sinus, and in the venous vascular structures of the posterior fossa. Thus, it was found that cerebral venous thrombosis due to Behçet disease could clearly be determined by the SWI sequence; in addition, thrombosis by the venous vascularity in veins of the posterior fossa were more visible than via the other MR sequences. The conclusion was made that SWI can promptly demonstrate cerebral venous thrombosis, contribute to the diagnosis, and provide useful additional information.Letter The Relationship Between Neuroinflammation, Mpv and Parkinson's Disease(Springer, 2013) Tanik, N.; Milanlioglu, A.; Okyay, M. Yavuz; Celikbilek, A.; Atalay, T.; Gocmen, A. Yesim; Aydin, M. NuriConference Object Rhythmic Tremor Artifact Mimicking Ictal Epileptiform Pattern on Eeg of Non-Epileptic Psychogenic Seizures(Wiley-blackwell, 2012) Tombul, T.; Milanlioglu, A.
