Browsing by Author "Noori, Hussein Ali"

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Optical, Electrochemical and Dft Studies of Donor-Acceptor Typed Indole Derivatives
(Elsevier, 2023) Carbas, Buket Bezgin; Noori, Hussein Ali; Kavak, Emrah; Kaya, Yasemin; Kivrak, Arif
The donor-acceptor type indole chromophore motif presents an interesting molecular architecture to the scientific world, unfortunately, as in every special and beautiful formation needed; their synthesis represents a synthesis challenge. In the current search, new donor-acceptor typed indole derivatives, 1-methyl-phenyl-3-aldehyde indole (HAN-1), 2-(((1-methyl-2-phenyl-1H-indol-3-yl)methylene)malononitrile ( HAN-2), 1-ethyl-2-phenyl-3-aldehyde indole (HAN-3), 2-((1-ethyl-2-phenyl-1H-indol-3-yl)methylene)malononitrile (HAN-4) were successfully synthesized and the results supported with FTIR and NMR spectra analysis. All the molecules undergo excited state intramolecular electron transfer with unique charge transfer reaction. Their electrochemical and optical properties were investigated in relation to the acceptor effect of functional groups on the indole units in the conjugated structure. Density functional theory (DFT) calculations exhibited that higher electron withdrawing ability strength resulted in decreased HOMO-LUMU gaps of the molecules. Futhermore, donor acceptor typed indole derivatives undergo irreversibly one electron oxidation in the medium of 0.1 M TBAPF(6)/ACN solution with a similar onset oxidation potentials. Both experimental and theoretical studies showed that the electron withdrawing ability of the molecules affect more LUMO energy level of the molecules. Moreover, they suggest that donor acceptor indole molecules herein are potential candidates for fabrication of dye synthesized solar cells. (C) 2022 Elsevier B.V. All rights reserved.
Synthesis of Donor-Acceptor Type of Indoles Via Condensation Reaction
(2022) Noori, Hussein Ali; Kıvrak, Arif
Hetero halkalı bileşikler sınıfından olan indol türevleri çeşitli hastalıkları tedavi etmek için kullanılır. Genellikle antibakteriyel, antiparaziter, antikanser, antiinflamatuar ve antitümör ilaçlar gibi pekçol biyolojik aktiviteye sahiptirler. Ilaç olarak kullanılan birçok indol türvide vardır. Bu çalışma, yeni indol türevlerinin tasarımı ve sentezi yapılmıştır. İlk olarak indol yapısına 3 konumundan aldehit fonksiyonel grubu Vielsmier Haack tepkimesi ile bağlanmıştır. Daha sonra güçlü elektron çeken gruplardan birisi olan siyano grupları kondenzasyon tepkimeleri ile yapıya bağlanarak, hedeflenen elektron çeken-elektron veren yapısına sahip yeni türevlerin sentezi gerçekleştirilmiştir. Anahtar kelimeler: Elektron verici-alıcı, Fischer, İndol, Kondenzasyon reaksiyonu, Sentez.