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Browsing by Author "Oagaz, Jeger Ali"

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    Synthesis and Biological Properties of Novel 1-Methyl Hydrazine Analogues
    (Tubitak Scientific & Technological Research Council Turkey, 2018) Kivrak, Arif; Yilmaz, Can; Konus, Metin; Koca, Halil; Aydemir, Selahattin; Oagaz, Jeger Ali
    1-Methyl-2-(2-(prop-2-yn-1-yloxy)benzylidene)hydrazine analogues were readily prepared in good yields by the reaction of 2-(prop-2-yn-1-yloxy)benzaldehydes and methyl hydrazine. The reaction tolerates a variety of substituents on the 2-hydroxybenzaldehyde to form nitro-, halo-, methoxy-, and naphthyl-substituted 1-methyl-2-(2-(prop-2-yn-1-yloxy)benzylidene)hydrazines. The in vitro antioxidant capacity measurements revealed that among all the analyzed hydrazine analogues that surpassed the Trolox standard, 1-(2-(but-3-ynyl)-5-nitrobenzylidene)-2-methylhydrazine had the maximum value, which was approximately 1.7 times that of Trolox.