Browsing by Author "Odabaş, D."

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Bacillus Anthracis Sepsis in a Newborn
(Lippincott Williams and Wilkins, 2000) Özkaya, E.; Kirimi, E.; Berktas, M.; Odabaş, D.
Central Diabetes Insipidus Following Intracranial Hemorrhage Due To Vitamin K Deficiency in a Neonate
(2005) Çaksen, H.; Odabaş, D.; Kaya, A.; Cesur, Y.; Kiymaz, N.; Etlik, Ö.; Turhan, S.
A previously healthy 30-day-old girl presented with seizures, irritability and inability to sleep for three days. Vitamin K was not given just after birth. She was lethargic. A multifocal clonic seizure was evident during examination. Anisocoria was diagnosed on eye examination. Brain magnetic resonance imaging showed intracerebral hemorrhage, ventricular dilatation, and hematoma in the left temporofrontal region extending to the hypothalamus. Central diabetes insipidus was diagnosed by water deprivation due to dehydration and hypernatremia, and then desmopressin was added to phenobarbital. The possible mechanism of central diabetes insipidus in our patient is damage of vasopressin pathway resulting from compression of hemorrhage. An operation of ventriculoperitoneal shunt was also performed due to hydrocephalus. While she was symptom-free except for neurological sequel during routine control examinations after discharging from hospital, the parents said that she died, most probably from bronchopneumonia, at the age of 7.5 months. In conclusion, we emphasize that prophylactic vitamin K should be administrated to all babies just after birth, and infants with intracranial hemorrhage should carefully be monitored for central diabetes insipidus.
Comparison of Low and High Dose of Vitamin D Treatment in Nutritional Vitamin D Deficiency Rickets
(Freund Publishing House Ltd, 2003) Cesur, Y.; Çaksen, H.; Gündem, A.; Kirimi, E.; Odabaş, D.
In this study, we compared three different therapy modes (150,000 IU, 300,000 IU, and 600,000 IU vitamin D p.o.) in infants with nutritional vitamin D deficiency rickets (VDR). Our purpose was to determine the most effective dosage of vitamin D with least side effects for treating VDR. The study included 56 patients, 3-36 months of age, with nutritional VDR and 20 age-matched control infants. In all infants, serum calcium, phosphorus, alkaline phosphatase, magnesium, serum 25-hydroxycholecalciferol, plasma intact parathormone levels and urinary Ca/creatine ratio were determined. Of 56 patients, 52 were able to be followed long-term. These patients were reexamined on the 3rd day, 7-10th day, and 25-30th day after treatment. On the 30th day post-treatment, we did not find any difference between the doses in the improvement of rickets. However, hypercalcemia was present in eight infants who had been administered 300,000 IU (two infants) and 600,000 IU (six infants) of vitamin D. In conclusion, our findings showed that 150,000 IU or 300,000 IU of vitamin D was adequate in the treatment of VDR, but 600,000 IU of vitamin D may carry the risk of hypercalcemia.
Hyponatremic Dehydration: an Analysis of 78 Cases
(2001) Çaksen, H.; Odabaş, D.; Şar, A.; Çelebi, V.; Arslan, S.; Kuru, M.; Abuhandan, M.
Our purpose was to determine the frequency of convulsion in children with hyponatremic dehydration (HD). We also investigated whether or not there was a relationship between the severity of hyponatremia and the degrees of malnutrition in our region (Eastern Anatolia of Turkey) in where malnutrition is frequently observed. In this study, the clinical and laboratory findings of 78 patients with diarrhoea (acute, persistent or chronic diarrhoae) and HD were studied. When diarrhoea lasts longer than 2 and 4 weeks they were accepted as persistent and chronic diarrhoea, respectively. Patients were said to have HD if they had the clinical findings of dehydration associated with hyponatremia [Serum sodium (SNa) <130 mmol/L)]. Nutritional status of the children was assessed by the Gomez classification using weight for age; it was accepted as normal those were between 90%-110%, mild malnutrition 75%-89%, moderate malnutrition 60%-74% and severe malnutrition <60%. Of 78 patients, 40 were boys, 38 were girls. The age and weight of the patients ranged from 40 days to 36 months (8.94 ± 5.49 months) and from 2000 to 10300 g (5535.25 ± 1702.10 g) respectively. All patients except four had malnutrition; 15 (20.3%) had mild malnutrition, 30 (40.5%) had moderate malnutrition and 29 (39.2%) had severe malnutrition. Forty-seven patients had acute, 16 patients had persistent, and 15 patients had chronic diarrhoea. SNa levels were between 104 and 129 mmol/L (121.21 ± 6.12 mmol/L). There was not statistically a significant difference between SNa level and the degree of malnutrition, and SNa level and the types (acute, persistent or chronic) of diarrhoea (p > 0.05). Of 78 patients, 12 (15.3%) patients had convulsion, of whom eight had convulsion associated with fever. Convulsion was noted in nine (19.1%) and three (18.7%) patients with acute and persistent diarrhoea, respectively (p > 0.05). Also, we observed that when hyponatremia was severer, convulsions tended to be more occurring (p < 0.05). Five (6.4%) children died and all of them had severe malnutrition and septicemia. We determined that the frequency of convulsion in HD was 15.3% (12/78), and there was not a difference between the cases of acute, persistent and chronic diarrhoea for the frequency of convulsion. We also found a significant difference was not present between SNa level and the degree of malnutrition, and between SNa level and the types (acute, persistent or chronic) diarrhoea. However, we observed that when hyponatremia was severer, convulsions tended to be more occurring.
Measles Is Still a Severe Problem in Eastern Turkey
(2004) Çaksen, H.; Odabaş, D.; Köse, D.; Şar, Ş.; Tuncer, O.; Ataş, B.
In this study, we reviewed the demographic and clinical findings of 143 children with measles to draw attention the importance of measles and its complications in Eastern Turkey. Of 143 patients, 75 (52.5%) were boys, 68 (47.5%) were girls. The patients' age ranged from 5 months to 13 years (3.97 ± 3.11 years). The peak of admissions (37%) occurred in the age range five to 24 months. The majority of the cases (84.7%) were not immunized against measles. Of 143 cases, 104 (72.7%) cases were malnourished. Of 143 children,57(40%) children had one or more complication of measles and the most common complication was pneumonia. Two (1.3%) children died In conclusion, our findings showed that measles and its complications were severe problem in our country. We think that it is primarily related to very low socioeconomic status of our region.
Relapsing Hepatitis a in Children: Report of Two Cases
(2002) Arslan, Ş.; Çaksen, H.; Öner, A.F.; Odabaş, D.; Rastgeldi, L.
Viral A hepatitis is a self-limited infection occurring predominantly among children usually as an anicteric often subclinical illness. After a stage of typical hepatitis A, a biphasic or relapsing form of viral hepatitis A (R-HA) may occur. Although relapse occurs in 3 to 21% of patients with acute hepatitis A, the patients with R-HA have been unusually reported in the literature. In this article, we report two children with R-HA because of unusual presentation and to draw attention to the importance of R-EA.