Browsing by Author "Oksuz, Mustafa"

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The Effect of the Active Ingredient Thymoquinone on Flap Viability in Random Pattern Flaps in Rats
(Springer, 2016) Kocak, Omer Faruk; Bozan, Nazim; Oksuz, Mustafa; Yuce, Serdar; Demir, Canser Yilmaz; Bulut, Gulay; Ragbetli, Murat Cetin
Thymoquinone (TQ) is a plant extract that has been shown to have antioxidant, anti-inflammatory, angiogenic, antimicrobial, and anticarcinogenic effects. The aim of this study is to research how the use of TQ affects flap viability. 42 rats were placed into 6 groups, with 7 rats in each. A 3 x 10 cm McFarlane flap model was used on the test animals. The sham group had used neither surgical nor TQ treatment. The control group had surgery but no treatment afterwards. The preoperative TQ group was given oral doses of 2 mg/kg. TQ for 10 days preoperatively with no treatment after the surgical procedure. The postoperative TQ group received oral doses of 2 mg/kg TQ for 10 days after the surgical process. The preoperative + postoperative (pre + postoperative) TQ group was given oral doses of 2 mg/kg TQ for 10 days both preoperatively and postoperatively. Finally, the dimethylsulfoxide group received 10 mg/kg dimethylsulfoxide (DMSO) for 10 days both preoperatively and postoperatively. Ten days after surgery the findings were evaluated. The average rates of necrosis were found to be 29.7 % in the control group, 19.18 % in the preoperative TQ group, 13.05 % in the postoperative TQ group, 8.42 % in the pre + postoperative TQ group, and 29.03 % in the DMSO group. The experimental groups had better area measurement, histopathological, and electron microscopic results than the control group (All; p < 0.05). We believe that, because of its antioxidant, anti-inflammatory, and angiogenic properties, thymoquinone is an agent that can prevent ischemia-reperfusion damage and, therefore, prevent necrosis.
Effects of Ozone Pretreatment on Viability of Random Pattern Skin Flaps in Rats
(Taylor & Francis Ltd, 2015) Oksuz, Mustafa; Yuce, Serdar; Kocak, Omer Faruk; Canbaz, Yasin; Ragbetli, Murat Cetin; Mercantepe, Tolga
Background: Medical ozone is a chemical agent that consists of three oxygen atoms and has antioxidant, angiogenic and vasodilator effects. This study evaluated the effects of medical ozone pre-treatment on flap survival. Materials and methods: Rats were divided into four groups of 10 rats each and a 9 x 3 cm McFarlane flap was used. Sham group: Neither surgical nor ozone pretreatment was used. Control group: No pretreatment was used after surgery. Preoperative ozone group: Preoperative 1 mg/kg ozone was given intraperitoneally for 7 days. No pretreatment was used after surgery. Postoperative ozone Group: Postoperative 1 mg/kg ozone was given intraperitoneally for 7 days. After postoperative 1 week, all groups were evaluated by surface area measurement, histopathology and electron microscopy. Results: With the experimental McFarlane flap model, the experimental groups had better surface area measurements, along with histopathological and electron microscopic results when compared with the control group. Conclusion: Medical ozone had positive effects on flap survival due to its antioxidant, angiogenic and vasodilator qualities.
A Forgotten Disease "leprae" and Limb Lesions
(Medknow Publications & Media Pvt Ltd, 2016) Oksuz, Mustafa; Kocak, Omer Faruk; Yuce, Serdar; Topkara, Adem; Sultanoglu, Yilmaz
Leprae, which is a forgotten infectious disease, presents with primary findings of skin lesions and peripheral nerve lesions. Neuropathic ulcers are frequently found and may cause deformities, particularly in the extremities. It should not be forgotten that malignant tumors seen on the floor of chronic ulcers can also be seen on the floor of neuropathic ulcers depending on leprae. In our study, a 61-year-old male patient with an ulcerated and unhealed lesion in the volar surface of the second finger of his right hand that existed for approximately 6 months is presented. Although leprae is not common these days, early defect repairs will prevent osteomyelitis and sequelae of amputation, depending on the malignancy in these patients.
Groin Flap Experience in the Reconstruction of Soft Tissue Defects of the Hand
(Medknow Publications & Media Pvt Ltd, 2016) Yuce, Serdar; Oksuz, Mustafa; Ersoz, Muhammet Eren; Kocak, Omer Faruk; Kahraman, Ahmet; Isik, Daghan; Atik, Bekir
Objective: Pediculated groin flap has been playing an important role in hand reconstructive surgery for a long time. In this study, the cases where pediculated groin flap in the reconstruction of soft tissue defects of the hand was used are presented in terms of literature. Material and Methods: The cases included in the study where a groin flap was used for hand defects between 2010 and 2014 in the Plastic, Reconstructive, and Aesthetic Surgery Department. The age, gender, reason of defect, its localization, groin flap size, donor area closure method, flap separation time, other treatments, and complications were thoroughly examined. Results: Twenty-two groin flaps were used in 13 male and 7 females. It was used to close the amputated part in 8 patients as a result of finger amputation and degloving injury, in 3 patients as a result of hand and finger crush defect, in 1 patient as a result of burn finger defect, in 5 patients for extension contracture, and in 3 patients for flexion contracture due to burn sequel. Flap loss was not recorded in any of the cases. Conclusion: Pediculated groin flap is a good alternative that can be easily and safely used in suitable cases and has an important place in the reconstruction of hand defects.
Incidental Findings in Trauma Patients: Bifid Nervus Medianus
(Medknow Publications & Media Pvt Ltd, 2016) Kocak, O. Faruk; Oksuz, Mustafa; Ersoz, M. Eren; Yuce, Serdar
Investigation of Skin Cancer in the Geriatric Age Group
(Gunes Kitabevi Ltd Sti, 2014) Yuce, Serdar; Oksuz, Mustafa; Ersoz, Muhammed Eren; Kahraman, Ahmet; Isik, Daghan; Atik, Bekir
Introduction: With the increase in lifespan, age related diseases including cancer also increase. With this in mind, in our study we evaluated treatment methods and results of patients who were older than age 65 and operated for skin cancer in the Plastic Surgery Clinic. Material and Method: Patients older than age 65 who were operated between 2010 and 2014 for skin cancer in the Department of Plastic Surgery were included in our study. Age, gender, diagnosis, localization, operation, lymph node dissection and additional treatments were analysed. Results: 91 geriatric patients with skin cancer were detected. The average age of patients was 74.4 years. 47 (51.65%) patients were female; 44 patients (48.35 %) were male. With respect to diagnosis, 58 (63.74%) had basal cell carcinoma, 27 (29.67%) had squamous cell carcinoma, and in 6 (6.59%) patients cutaneous melanoma was detected. A review of surgical operations showed that 22 (24.17%) patients had lesion excision + primary suturation, 19 (20.88%) had lesion excision + graft repair, 48 (52.75%) had lesion excision + local flap repair, and 2 (2.20%) had amputation. Conclusion: In recent years, skin cancer, especially the incidence and mortality of cutaneous melanoma, has been seen more frequently in elders, compared to younger patients. In health controls, the mortality of skin cancer may be reduced by taking into account the geriatric age group.
An Unexpected Long-Term Complication of Genital Burn in a Child: Secondary Cryptorchidism
(Turkish Assoc Trauma Emergency Surgery, 2018) Oksuz, Mustafa; Deliaga, Hasan; Topkara, Adem; Kocak, Omer Faruk
Genital and perineal burns are rare and challenging injuries with serious long-term complications. Involvement of the testes is a sign of severity. There is limited knowledge in the literature about the management of complications and testes involvement in genital and perineal burns. In this report, we present the case of an 8-year-old boy with secondary cryptorchidism due to burn contracture who was treated by increasing the scrotal volume by Z-plasties, skin graft, and orchidopexy.
Use With Tissue Expander Face, Scalp and Neck Reconstruction
(Modestum Ltd, 2015) Yuce, Serdar; Oksuz, Mustafa; Ersoz, Muhammet Eren; Kahraman, Ahmet; Isik, Daghan; Atik, Bekir
The tissue expander has found widespread use in reconstructive surgery. The donor area is needed, the recipient site with similar characteristics (color, thickness, hair follicle) features, minimal scarring and leads to donor site morbidity. In our study, presented face, scalp and neck reconstruction results obtained with the use of expander. The face, scalp and neck areas expander was used to evaluate patients in the Plastic, Reconstructive and Aesthetic Surgery Department of Yuzuncu Yil University. Age, gender, expander indication, defect or scar area localization, expander residential area, expander shape, volume, valve location (internal-external), expansion time, major and minor complications were reviewed. 30 number expanders were used in 17 patients (8 male, 9 female patients). Expanders were used burn sequelae in 14 patients, tumor-related defects in 2 patients and due to giant hairy nevus in 1 patient. The expanders are scalp (19 cases), face (3 cases), supraclaviculer (7 cases) and the neck (1 case) has to be placed. In 4 of 17 patients (three major and one minor) complications were encountered. Use the expander is a good option especially in the reconstruction of soft tissue defects in the head and neck region.
A Village in the Ottoman Jerusalem: Beit Jala (16th Century)
(Afyon Kocatepe Univ, 2022) Oksuz, Mustafa
Modern-day Beit Jala, which hosts a Christian and Muslim population, is a city located in Palestine, a region at the hearth of world politics. It is possible to find information about the past of the city in the archives of the Ottoman Empire, which ruled the region for four centuries. Various documents that have survived to the present day, especially cadastral surveys, muhimme and foundation registers and court records, contain important information about Beit Jala, which was a Christian village in the sixteenth century. Based on these sources, this study aims to contribute to the understanding of the historical aspect of today's Palestine issue. Beit Jala was administered as a village in the Jerusalem district of the Jerusalem Sanjak under the Ottoman administration in the sixteenth century. This village, where only the Christian population lived, had close relations with the city due to its location. The troubles that occurred in the region during the Ottoman-Mamluk conflict had a negative impact on this place. It is seen that the region entered into a recovery process with the measures taken after Suleiman the Magnificent (1520-1566) ascended the throne. It is understood that the stable structure that was created began to shake after the death of this sultan and the population of the village decreased. Although the detailed cadastral record register dated 1005h/1596-97 of the reign of Mehmed III (1595-1603) provides some clues about positive developments in terms of population in the village, the thirty-four-year gap between this register and the previous record makes it difficult to make a definitive evaluation. When we look closely at Beit Jala in the first century of Ottoman rule, it is possible to understand that there were some administrative changes. Beit Jala, which formed a part of the financing of the Haremeyn charity of the Mamluk Sultan Kayitbay, had become a fully-fledged foundation village after Hurrem Sultan's allocation to the Imaret Foundation in Jerusalem. While this change tightened its connection with the city, the attention of both the administrators in the sanjak and the administrators in the capital was on this place since it became one of the sources that financed a prestigious project of the empire. Its stability, therefore, was naturally of great importance. Ultimately, this transformation made Beit Jala even more dependent on Jerusalem and started to turn the wheels of production for the city/foundation economy. The sources offer a wealth of information on the agricultural product here. It is seen that various agricultural activities related to olive production, beekeeping and goat breeding were also carried out in the village where various plants, especially wheat, barley, olive and viticulture, were cultivated. Taxes on crops have changed over the century, sometimes to produce more income. This was a sign that a flexible mode of production had been adopted by the villagers . They have updated themselves in this regard by closely following the changes and transformations in the market. Undoubtedly, the ecological conditions and the change/transformation that took place in the region played a major role in the adoption of this attitude. In addition to not being closed to the outside world, the residents of Beit Jala preferred to go and settle in Jerusalem over time. When the situation worsened and they were forced to leave the city, they returned to their villages. As a matter of fact, there are signs confirming this situation in the statements in the cadastral records. There is enough information in the court records regarding the adventures of the residents of the city. Considering the flexible agricultural activities of the Muslims in the village, it is understood that the villagers belonging to the Orthodox sect do not have religious fanaticism. The poll tax paid by the Christians increased over time, and the capitation rate was determined as 70 akche during the conquest, considering the interests of the people. After the improvement of the economic situation in the village, the amount was increased to 80 akche and this amount was kept for most of the century. Considering the financial situation of the state and the depreciation of the akche, the villagers were obliged to pay the jizya as 90 akche at the end of the sixteenth century. In terms of other taxes, especially the jizya, the imperial administrators did not adopt a taxing practice that harass the people and tried to prevent all the practices they deemed illegal.