Browsing by Author "Ozbek, M."

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Clinicopathological and Biochemical Evaluation of Feline Infectious Peritonitis in Turkish Van Cats
(Hellenic veterinary Medical Soc, 2022) Ozbek, M.; Ozkan, C.; Kaya, A.; Yildirim, S.; Kozat, S.; Akgul, Y.
This study was performed to evaluate serum homocysteine and nitric oxide levels in cats with Feline Infectious Peritonitis and present biochemical and clinicopathological alterations related to the disease. The material of this study consisted of 30 Turkish Van Cats of different ages and genders with Feline Infectious Peritonitis that were definitely diagnosed by post-mortem examinations and immunohistochemistry. The control group consisted of 6 healthy Turkish Van Cats of different ages and genders that were brought for routine clinical examination. Cats in the study group had clinical findings such as loss of appetite, weight loss, high fever, persistent fever, jaundice, dehy-dration, vomiting, respiratory system symptoms, anemia, nervous findings, uveitis, and ascites. These cats were mon-itored and following the death, post-mortem examinations were performed and cases with a definitive diagnosis were included in the study. Among the cats consisting study group, while 25 had the dry form of the disease, 5 had wet form. According to the hematological results, there was a statistically significant reduction in platelet counts. The biochemi-cal results showed statistically significant alterations that creatinine, aspartate aminotransferase, alkaline phosphatase, creatine kinase myocardial band, homocysteine, and nitric oxide concentrations were higher than the control group. Besides albumin concentrations were lower and the albumin/globulin ratio was 0.53. As a result; this is the first detailed study in Turkish Van Cats with Feline Infectious Peritonitis that evaluated clinical, hematological, biochemical, and pathological findings. Furthermore, serum homocysteine and nitric oxide levels were evaluated for the first time in cats with vasculitis which is the most important complication of the disease. It is concluded that the evaluation of serum homocysteine and nitric oxide concentrations in Feline Infectious Peritonitis may assist the antemortem diagnosis of e disease.
Effect of Fluid Therapy and Oxygen Application on Venous Blood Parameters of Diarrheic Calves With Hyperkalemia
(Hellenic veterinary Medical Soc, 2024) Ozbek, M.; Ozkan, C.; Altan, Y.
The purpose of this study was to evaluate the effect of oxygen therapy on clinical, hematological, biochemical and venous blood gases in diarrheic calves with hyperkalemia in addition to routine diarrhea and fluid-electrolyte therapy. Animal material was consisted of 20 diarrheic and hyperkalemic calves, with different ages. Diarrheic calves with serum potassium levels greater than 6 mmol/L were included in the study following the clinical examination and analysis results. The calves were divided into 2 groups. Calves in the 1(st )Group (n=10) received routine diarrhea and fluid-electrolyte treatment and calves in the 2(nd) Group (n=10) received routine diarrhea and fluid-electrolyte treatment as well as oxygen applications by mask. Blood samples were taken from the animals for blood gases, hematological and biochemical analyses. The decrease in heart and respiratory rate was more significant in the 2(nd) group when compared to the 1(st) group. When statistically comparing the same time periods of both two groups, heart rates were lower in the oxygen applied group and this decrease was statistically significant. In the 2(nd )group; decrease in WBC, Lym, RBC, Hct%, Hb, MCH, MCHC and MCV levels and increase in Neu and THR levels were statistically significant. Increase in pH, PO2, sO(2), Na, Cl, cHCO(3) and decrease in pCO(2), K, Lac, cBaseEcf and AnionGap were detected. When comparing the same time period of 1(st) and 2(nd) groups, there was statistically significant differences were determined on the 5th hour in K, on the 24(th) hour in pH and pO(2) values. Particularly in the oxygen applied group; there were statistically significant alterations in pH, pCO(2), pO(2), sO(2), K and Lac. Among biochemical parameters; decrease in LDH and TP in the 2(nd) group, and decrease in TP and ALB in the 1(st) group were found to be statistically significant. As a result, oxygen administration in addition to routine diarrhea treatment is thought to have positive effects on pH, pO(2), pCO(2), sO(2), K. Based on the results obtained in this study, it was concluded that oxygen therapy would be beneficial for calves with diarrhea and hyperkalemia. It is believed that this study will lead to future studies on calves with diarrhea and will shed light on these studies.
Evaluation of Cobalt, Copper, Manganese, Magnesium and Phosphorus Levels in Cows With Clinical Ketosis
(Univ Agriculture, Fac veterinary Science, 2016) Kaya, A.; Ozkan, C.; Kozat, S.; Akgul, Y.; Ozbek, M.
The objective of this study was to examine the association between 13-hydroxybutyrate (BHBA) and glucose, cobalt (Co), copper (Cu), manganese (Mn), magnesium (Mg), and phosphorus (P) in cows with clinical ketosis and control group. At the beginning; while serum glucose levels, Co, Cu, Mn, Mg and P concentrations in cows with clinical ketosis were lower, BHBA levels were higher than control group. At the 3rd day after the treatment, serum Co, Cu, Mn and P concentrations were lower in cows with clinical ketosis than control group. According to these results, mineral level decrease was detected in cows with ketosis. It is thought that there should be more study performed about the contribution of minerals to the treatment of ketosis. This study will provide an insight to the studies will be performed in this respect. (C) 2015 PVJ. All rights reserved