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Browsing by Author "Ozcelik, Sinem"

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    Chronic Pain in Multiple Sclerosis: a Two-Year Longitudinal Study
    (Sage Publications Ltd, 2023) Karakas, Hilal; Ozdogar, Asiye Tuba; Ozcelik, Sinem; Kahraman, Turhan; Ozakbas, Serkan
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    Comparative Analysis of Restless Legs Syndrome and Neuropathic Pain Impact on Walking and Balance in Multiple Sclerosis: Clinical and Radiographic Insights
    (Sage Publications Ltd, 2024) Ozdogar, Asiye Tuba; Kaya, Ergi; Ozcelik, Sinem; Unal, Gozde Deniz; Ozakbas, Serkan
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    Comparison of Two Commonly Used Depression Questionnaires Based on Reflecting Physical and Cognitive Functions in People With Multiple Sclerosis
    (Sage Publications Ltd, 2023) Ozdogar, Asiye Tuba; Sagici, Ozge; Aslan, Taha; Ozcelik, Sinem; Ozakbas, Serkan
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    Do Brand-Name and Generic-Brand Drugs of Dimethyl Fumarate Show Similar Efficacy and Safety Profiles in Relapsing-Remitting Multiple Sclerosis
    (Sage Publications Ltd, 2023) Kaya, Ergi; Sagici, Ozge; Ozdogar, Asiye Tuba; Ozcelik, Sinem; Ozakbas, Serkan
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    Effects of Two Grams of Methylprednisolone in People With Multiple Sclerosis Who Received One Gram of Methylprednisolone for Relapses
    (Sage Publications Ltd, 2023) Alizada, Said; Ozcelik, Sinem; Dastan, Seda; Sagici, Ozge; Ozdogar, Asiye Tuba; Ozakbas, Serkan
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    Efficacy of Original Fingolimod Vs. Generic-Brand Drugs in Treating Multiple Sclerosis: a Comparative Study Using Real-World Data From Turkey
    (Sage Publications Ltd, 2023) Ozcelik, Sinem; Sagici, Ozge; Ozdogar, Asiye Tuba; Kaya, Ergi; Ozakbas, Serkan
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    Enhancing Disability Progression Assessment in Multiple Sclerosis: Introducing the Edss-Plus Score
    (Sage Publications Ltd, 2024) Ozcelik, Sinem; Ozdogar, Asiye Tuba; Alizada, Said; Cinar, Bilge Piri; Ozakbas, Serkan
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    Evaluating the Effectiveness of No Evidence of Disease Activity-3 in Managing Progression Independent of Relapse Activity and Relapse-Associated Worsening in Multiple Sclerosis
    (Sage Publications Ltd, 2024) Ozcelik, Sinem; Ozdogar, Asiye Tuba; Alizada, Said; Ozakbas, Serkan
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    Article
    Factors Related To Restless Leg Syndrome in Neuromyelitis Optica Spectrum Disorder
    (Elsevier Sci Ltd, 2025) Ozdogar, Asiye Tuba; Karakas, Hilal; Dastan, Seda; Kaya, Ergi; Sagici, Ozge; Ozcelik, Sinem; Ozakbas, Serkan
    Objective: Although the feeling of unrest in the legs is frequently reported as a sensory symptom by people with Neuromyelitis Optica Spectrum Disorder (NMOSD, pwNMOSD), there are limited studies to investigate the relationship between Restless Legs Syndrome (RLS) and NMOSD. The study's primary aim is to determine the frequency and severity of RLS in pwNMOSD. The other aim is to compare the sleep quality, daytime sleepiness level, quality of life, fatigue, magnetic resonance imaging results, and cognitive functions in RLS-positive and negative pwNMOSD. Methods: The RLS diagnosis was performed with RLS-Diagnostic Index criteria. The patient-reported outcomes were RLS Severity Rating Score, The Preference-Based Multiple Sclerosis Index (PBMSI), the Modified Fatigue Impact Scale (MFIS), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS). Cognitive function was assessed with The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) battery. The neurologist recorded the demographic and clinical characteristics of the participants. Results: The RLS was detected in 17 (21.5 %) of the 79 pwNMOSD participants. Fifty-six pwNMOSD were reached to assess cognitive functions and patient-reported outcomes. The rate of RLS was 60.71 % in this group. The PBMSI, PSQI, MFIS, and ESS scores were significantly different in RLS-positive participants than in RLS-negative (p < 0.05). Moreover, while participants' visuospatial and verbal learning was similar, the processing speed was slow in the RLS-positive group (p > 0.05). Conclusions: Our preliminary results have shown that the RLS frequency is high in pwNMOSD. This study suggests a connection between the presence of RLS and worse sleep quality, fatigue level, processing speed, and quality of life in the NMOSD population. However, our results should be considered with the fact that the study has a small sample size and needs future studies to confirm our results for solid evidence.
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    Identifying the Related Factors With Restless Legs Syndrome in Persons With Multiple Sclerosis
    (Sage Publications Ltd, 2023) Ozdogar, Asiye Tuba; Karakas, Hilal; Aldemir, Enes; Dastan, Seda; Ozcelik, Sinem; Cilingir, Vedat; Ozakbas, Serkan
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    Objective Assessment To Predict the 12-Item Ms Walking Scale: Timed 25-Foot Walk or Six Spot Step Test
    (Sage Publications Ltd, 2023) Dastan, Seda; Ozdogar, Asiye Tuba; Ozcelik, Sinem; Baba, Cavid; Ozakbas, Serkan
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    Pregnancy in Multiple Sclerosis and Its Impact on Disease Course
    (Sage Publications Ltd, 2024) Aslan, Taha; Kaya, Ergi; Simsek, Yasemin; Ozcelik, Sinem; Ozdogar, Asiye Tuba; Ozakbas, Serkan
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    Recommendation Regarding Health-Related Quality of Life Measurement in People With Multiple Sclerosis
    (Sage Publications Ltd, 2023) Ozdogar, Asiye Tuba; Sagici, Ozge; Ozcelik, Sinem; Dastan, Seda; Baba, Cavid; Ozakbas, Serkan
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    Which One Is More Progressive; Primary, or Secondary Progressive Multiple Sclerosis
    (Sage Publications Ltd, 2024) Ozcelik, Sinem; Kaya, Ergi; Ozdogar, Asiye Tuba; Ozakbas, Serkan