Browsing by Author "Ozdemir, Nihal"

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The Association of Left Ventricular End-Diastolic Pressure With Global Longitudinal Strain and Scintigraphic Infarct Size in St-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention
(Springer, 2021) Cap, Murat; Erdogan, Emrah; Karagoz, Ali; Den Hartigh, Ozden Savas; Acar, Rezzan Deniz; Gecmen, Cetin; Ozdemir, Nihal
Left ventricular end-diastolic pressure (LVEDP) is an independent predictor for prognosis in ST-elevation myocardial infarction (STEMI) patients. We aimed to investigate the relationship of admission LVEDP measured after a successful primary percutaneous coronary intervention (pPCI) with scintigraphic infarct size (IS) and global longitudinal strain (GLS), a strong predictor of IS, in STEMI patients. A total of 62 consecutive patients with STEMI were enrolled in the study. LVEDP measurements were performed after pPCI in patients who had TIMI-3 flow. Echocardiography was performed 24 h after pPCI and repeated 3 months later. GLS was calculated as an average peak strain from the 3 apical projections. IS was evaluated at the third month by technetium 99m sestamibi. The mean age was 56 +/- 8 years in the study population. The mean LVEDP was found 19.4 +/- 4.4 mmHg. Median IS was 4% (0-11.7 IQR).The mean GLS at the 24th hour and the third month were found to be - 15.4 +/- 2.8 and - 16.7 +/- 2.5 respectively. There was a moderate negative correlation between LVEDP and GLS (24th-hour p < 0.001 r = - 0.485 and third-month p < 0.001 r = - 0.489). LVEDP had a moderate positive correlation with scintigraphic IS (p < 0.001 r = 0.545). In the multivariable model, we found that LVEDP was significantly associated with scintigraphic IS (beta coefficient = 0.570, p = 0.008) but was not associated with the 24th hour (beta coefficient = 0.092, p = 0.171) and third month GLS (beta coefficient = 0.037, p = 0.531). This study demonstrated that there was a statistically significant relationship between LVEDP and scintigraphic IS, and IS was increased with high LVEDP values. However, there was not a relationship between LVEDP and GLS.
Early Systolic Lengthening Is Associated With Syntax Score in Patients With Non-St Acute Coronary Syndrome
(Kare Publ, 2024) Unkun, Tuba; Gecmen, Cetin; Cap, Murat; Izci, Servet; Erdogan, Emrah; Onal, Cagatay; Ozdemir, Nihal
Background: Early systolic lengthening is a echocardiographic strain parameter previously used to determine the lesion severity in patients with stable coronary artery disease. In the present study, we aimed to evaluate the relationship between early systolic lengthening and anatomic SYNTAX score in troponin (-) and (+) groups among patients with non-ST-elevation acute coronary syndrome (ACS). Methods: A total of 95 patients diagnosed with non-ST-elevation ACS were included in the prospective, non-randomized, single-center study. The patients were categorized into 2 groups as troponin (+) and troponin (-). The patients were evaluated in terms of echocardiographic, clinical, and angiographic parameters. Results: The baseline characteristics, including age (58 +/- 13 vs. 60 +/- 10 respectively, P=.340), a history of hypertension (67.1% vs. 64%, respectively, P=.479), diabetes (28.6% vs. 32%, respectively, P=.467), global longitudinal strain (-14.37 +/- 5.11 vs. -16.42 +/- 3.93, respectively, P=.095), left ventricular ejection fraction (58.71 +/- 8.73 vs. 57.20 +/- 8.70, respectively, P=.263), and E/e' (8.44 +/- 2.13 vs. 8.33 +/- 1.99, respectively, P=.785), were similar between troponin (+) and troponin (-) groups. Left ventricle end-systolic diameter (3.2 +/- 0.78; 3.50 +/- 0.74 vs. 3.2 +/- 0.78, respectively, P=.031), left ventricle end-systolic volume (55.57 +/- 32.17 vs. 38.28 +/- 13.63, respectively, P=.013), left ventricle end-diastolic volume (115.31 +/- 49.54 vs. 91.23 +/- 20.57, respectively, P=.042), the rate of early systolic lengthening (65.7% vs. 28%, respectively, P=.001), the duration of early systolic lengthening (24.02 +/- 31 ms vs. 15.56 +/- 30.19 ms, respectively, P=.009), and the SYNTAX score (16 +/- 11 vs. 10 +/- 10, respectively, P=.023) were higher in the troponin (+) group. Furthermore, a significant correlation was found between early systolic lengthening and SYNTAX score (r = 0.43, P < .001). Conclusion: The rate and duration of early systolic lengthening were higher in patients in the troponin (+) group. Early systolic lengthening is related to SYNTAX score in patients with non-ST-elevation ACS.