Browsing by Author "Ozdemir, Pinar"

Now showing 1 - 2 of 2

The Comparison of Aripiprazole and Risperidone Augmentation in Selective Serotonin Reuptake Inhibitor-Refractory Obsessive-Compulsive Disorder: a Single-Blind, Randomised Study
(Wiley, 2011) Selvi, Yavuz; Atli, Abdullah; Aydin, Adem; Besiroglu, Lutfullah; Ozdemir, Pinar; Ozdemir, Osman
Objective To investigate the comparative efficacy of aripiprazole and risperidone as augmenting agents in the treatment of obsessive-compulsive disorder (OCD) patients who did not show a >= 35% decrease in the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) after 12-week monotherapy with selective serotonin reuptake inhibitors (SSRIs). Methods The study consists of two different periods of treatment: a 12-week prospective period to determine resistance to SSRI treatment and an 8-week single-blind addition period for refractory patients only. Ninety patients were randomly assigned to receive one of the SSRI treatments. Sixty-nine patients (76.6%) completed the 12-week SSRI monotherapy period. Forty-one patients (59.4%) were considered refractory and were randomised to receive either risperidone (20 patients, 3 mgr daily) or aripiprazole (21 patients, 15 mgr daily) as augmentation to SSRI treatment. Sixteen patients (76.2%) in the aripiprazole group and 18 patients (84%) in the risperidone group completed the 8-week treatment period. Results Eight patients (50%) in aripiprazole and 13 patients (72.2%) in risperidone group met response criteria of Y-BOCS decrease >= 35% at the end of the study. The risperidone group showed a significant improvement in Y-BOCS obsession scores compared with aripiprazole. Conclusions The present findings suggest that risperidone may be more effective than aripiprazole. Copyright (C) 2011 John Wiley & Sons, Ltd.
Traumatic Experiences, Dissociation and Attitudes Toward Delinquency in the Juvenile Male Delinquents
(Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2011) Ozdemir, Osman; Polat, Fatih Hakan; Besiroglu, Lutfullah; Selvi, Yavuz; Ozdemir, Pinar; Atli, Abdullah; Akbayram, Sinan
Objective: In this study the factors associated with juvenile delinquency were investigated by focusing on childhood trauma and dissociative experiences. Methods: Forty male adolescents (13-15 years old) referred to Yuzuncu Yil University, Medicine Faculty, Department of Psychiatry for forensic psychiatric evaluation and 40 male adolescents with mild infectious disease from pediatric outpatient clinic as control subjects were included in the study. The Childhood Trauma Questionnaire (CTQ), Adolescent Dissociative Experiences Scale (A-DES) and Attitudes toward Delinquency Scale (ADS) were administered to the children to collect data. Result: Compared to control group, emotional abuse scores of juvenile delinquents were significantly higher. There was no significant difference between groups for CTQ emotional abuse, physical abuse, sexual abuse, physical neglect and total scores. The ADS scores of juvenile delinquents were found significantly higher than control group. While the A-DES passive influence scores of juvenile delinquents significantly higher than control group, there were no differences for A-DES amnesia, absorbsion, depersonalition and total scores between two groups. The ADS scores of juvenile delinquents were significantly associated with CTQ scores except for physical neglect whereas the ADS scores of control subjects were only associated with emotional abuse scores. Lower economical level, A-DES passive influence, CTQ emotional neglect and ADS scores were significant predictors of delinquency in logistic regression model. Conclusion: Socioeconomical factors, traumatic experiences and passive influence tendency of juvenile boys are associated with attitudes toward delinquency and delinquent behaviours through reciprocal influences and feedback. (Anatolian Journal of Psychiatry 2011; 12:68-75)