Browsing by Author "Ozgocmen, S."

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Can the Patient-Reported Outcome Instruments Determine Disease Activity in Rheumatoid Arthritis
(Aepress Sro, 2011) Durmus, B.; Altay, Z.; Baysal, O.; Ersoy, Y.; Erdal, A.; Cevik, R.; Ozgocmen, S.
Objectives: The aim of this study was to investigate the indicative value of the patient-reported outcome instruments (PROs) on disease activity in rheumatoid arthritis (RA). Methods: Three hundred sixty eight patients with RA were included in this cross-sectional study. Disease activity was evaluated using both the Disease Activity Score 28 (DAS 28) and the Clinical Disease Activity Index (CDAI). Patients who had DAS 28 score <3.60 points and CDAI score <10.00 points were allocated into the "low disease activity" group and those who had DAS 28 score >= 3.60 points and CDAI score >= 10.00 points into the "moderate or high disease activity" group. The Health Assessment Questionnaire (HAQ), Nottingham Health Profile (NHP), Rheumatoid Arthritis Quality of Life (RAQoL), and Short Form 36 (SF 36) were used as PROs. Logistic regression analysis was used to find variables, which had an indicative value for disease activity. Results: HAQ, pain and emotional reaction subscales of NHP, and bodily pain, general health and social functioning subscales of SF 36 had independent indicative values, when DAS 28 was used as dependent variable. On the other hand, HAQ, pain and emotional reaction subscales of NHP, and general health and emotional role limitation subscales of SF 36 had indicative values when CDAI was used as dependent variable. DAS 28 and CDAI both showed HAQ as the parameter with the highest odds ratio (OR). But RAQoL had shown no independent indicative value for projecting disease activity. Conclusion: It was concluded that HAQ could determine disease activity in RA better than other PROs included in this study (Tab. 4, Ref. 36). Full Text in free PDF www.bmj.sk.
Spontaneous Regression of Herniated Lumbar Intervertebral Disc
(2006) Yilmaz, N.; Kaya, A.; Ozgocmen, S.; Kiris, A.; Kocakoc, E.
The aim of this report is to describe the very rare condition, spontaneous regression of herniated lumbar intervertebral disc, and the results of clinical follow-up and imaging modalities. A 53-year-old housewife presented with a 1-month history of low back and right leg pain. She had severe pain in her right leg radiating from the buttock to the heel and weakness of the right foot plantar flexion (rated 4/5 by manual motor testing), and straight-leg raising test was positive at 45° on the right side. Magnetic resonance imaging (MRI) revealed a large para-median extruded intervertebral disc at the L5-S1 level. She was followed up with medical treatments and physiotherapy and rehabilitation intervention. Follow-up MRI after 18 months since initial presentation revealed that extruded intervertebral disc material was completely resolved. In conclusion, the regression of the disc correlated with clinical improvement and was illustrated in follow-up magnetic resonance imaging. The exact mechanism underlying this condition is still unclear. As in our case, extruded lumbar intervertebral disc herniations may spontaneously regress and non-surgical conservative treatments may be appropriate. © 2006 Asia Pacific League of Associations for Rheumatology.