Browsing by Author "Ozgokce, F."

Now showing 1 - 9 of 9

Anti Microbial Activities of Leaves and Stems of Ulmus Minor Miller Subsp Minor
(Georg Thieme verlag Kg, 2011) Tag, O.; Yasa, I; Polat, E.; Ozgokce, F.; Karayildirim, T.
Anti-Inflammatory Activities of Diethyl-Ether Extracts of Helichrysum Plicatum Dc. and Tanacetum Balsamita L. in Rats
(Academic Journals inc, 2009) Karaca, M.; Ozbek, H.; Akkan, H. A.; Tutuncu, M.; Ozgokce, F.; Him, A.; Bakir, B.
The aim of this study was to investigate anti-inflammatory activity of the diethyl ether extract of Tanacetum balsamita L. subsp. (TB) and Helichrysum plicatum DC. subsp. (HP) in carrageenan-induced inflammation in rats. Lambda carrageenan (0.05 mL) was injected into the subplantar region of the right hind paw to induce inflammation. Control group and the reference group were administered isotonic saline solution and indomethacin, respectively. TB extract was injected in doses of 25, 50 and 100 mg kg(-1) in the groups TB-25, TB-50 and TB-100, respectively. HP-25 HP-50 and HP-100 groups were injected HP extract in doses of 25, 50 and 100 mg kg(-1). Before the injections and 3 h after the injections the volume of right hind-paw of rats was measured using a plethysmometer. TB and HP had anti-inflammatory effects matching to that of the reference agent at all doses. It was found that reduction in the inflammation was 95.21% with indomethacin, 51.93% with TB-25, 52.55% with TB-50, 61.51% with TB-100, 70.73% with HP-25, 73.15% with HP-50 and 82.90% with HP-100. Median effective dose (ED50) value of TB and HP were found to be 81.484 and 73.030 mg kg(-1), respectively. The results showed that Tanacetum balsamita L. subsp. and Helichrysum plicatum DC. subsp. had a significant anti-inflammatory activity.
Anti-Oxidant Properties of the Seeds of Gundelia Tournefortii L
(Wiley-blackwell, 2015) Sahin, S.; Coruh, N.; Ozgokce, F.
Antioxidant Capacities of Gundelia Tournefortii L. Extracts and Inhibition on Glutathione-S Activity
(Elsevier Sci Ltd, 2007) Coruh, N.; Celep, A. G. Sagdicoglu; Ozgokce, F.; Iscan, M.
Gundelia tournefortii L. is an important food source and a well-known medicinal plant in Eastern Anatolia. Therapeutic effects of medicinal plants are known to be closely related to their antioxidant capacities. Antioxidant activities of G. tournefortii, both for the aerial parts and seeds, were investigated by using both 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and lipid peroxidation inhibition methods. The seeds were found to have higher antioxidant potential than the aerial, with IC50 values of 0.073 mg/mL for DPPH scavenging and 0.146 mg/mL for lipid peroxidation inhibition capacities. In addition, total phenolic contents of the Gundelia tournefortii L. extracts, especially the seed extracts correlates to its high antioxidant activity with 105.1 +/- 8.7 mu g gallic acid equivalents (GAEs) per mg of seed extract. Plant extracts with high phenolics content are known to have important effects on various enzymes, as well as glutathione-S-transferases, which are important detoxification enzymes in phase 11 systems with an important role in developing multi-drug resistance to chemotherapy in tumour cells. Consequently, the effects of G. tournefortii extracts on crude cytosolic glutathione-S-transferase was also studied and the seed extracts have shown effective inhibition of cytosolic GST activity, with an IC50 of 97.51 mu g/mL. (c) 2005 Elsevier Ltd. All rights reserved.
Antioxidant Properties of Prangos Ferulacea (L.) Lindl., Chaerophyllum Macropodum Boiss. and Heracleum Persicum Desf. From Apiaceae Family Used as Food in Eastern Anatolia and Their Inhibitory Effects on Glutathione-S
(Elsevier Sci Ltd, 2007) Coruh, N.; Celep, A. G. Sagdicoglu; Ozgokce, F.
Therapeutic effects of several medicinal plants and vegetables, which are commonly used as food and in folk medicine against many disease, are well known. Antioxidant capacities of Heracleum persicum Desf., Prangos ferulacea (L.) Lindl., Chaerophyllum macropodum Boiss. species from Apiaceae family were evaluated by determining their effects on DPPH radical scavenging, and lipid peroxidation inhibition, as well as their total phenolic contents. Potential natural glutathione-S-transferase inhibitors have gained great importance in the last decade especially because of the role of glutathione-S-transferases in developing resistance to chemotherapy. Selected plants were therefore further investigated for their influence on the activity of glutathione-S-transferase enzyme. In comparing antioxidant capacities, P. ferulacea was found to be a better antioxidant than the other two plants in the family, with 50% inhibitory concentration values as 0.242 and 0.152 mg/ml for DPPH radical scavenging and lipid peroxidation inhibition, respectively. The same plants were also evaluated for their effects on GST activities and among the studied plants, P. ferulacea was the most efficient inhibitor with IC50 value of 79.25 mu g/ml for GST. C macropodum and H. persicum were less effective antioxidants than P. ferulacea with IC50 values of 0.623 and 0.438 mg/ml for DPPH radical scavenging, respectively, however, they could also be considered as potential GST inhibitors. (c) 2005 Elsevier Ltd. All rights reserved.
Antioxidative and Antiproliferative Effects of Turkish Rheum Ribes Aqueous Extract
(Wiley, 2006) Uyar, P.; Ozgokce, F.; Coruh, N.; Iscan, M.
Chromosome Numbers in Veroniceae (Plantaginaceae): Review and Several New Counts
(Missouri Botanical Garden, 2008) Albach, D. C.; Martinez-Ortega, M. M.; Delgado, L.; Weiss-Schneeweiss, H.; Ozgokce, F.; Fischer, M. A.
Chromosomal evolution in Veronica L and related genera (Wulfenia Jacq., Wulfeniopsis D.Y. Ilong. Paederola I. Lagolis Caertn. Picrorhiza Royle ex Benth and Veronicastrum Heist ex Fabr; Veroniceae. Plantaginaceae: formerly Scrophulariaccae) is presented. To this end, we conducted an extensive literature survey of more than 400 publications covering ca 300 out of 500 species in the tribe. We also report 44 new chromosome counts. Chromosome numbers of Veronica hispidula Boiss. & HueL (2n = 18.36) and V. reuteriana Boiss. (2n = 28.42) are reported for the first time, and both species exhibit intraspecific ploidy level variation. Other new counts confirm chromosome numbers reported previously. The evolution of chromosome numbers in Veroniceae is discussed in light of recent results from DNA-based phylogenetic analyses. Most of the subgenera of Veronica exhibit only one single basic number, i.e., x = 6,7,8,9,12,17, or 20.21. In this genus the putative ancestral base number of 9 has been reduced several times to 8 and 7 respectively (aneuploidy/dysploidy) often associated with transition to annual life history. In contrast no unambiguous increase of chromosome base number has been inferred. A table that includes all species of Veroniceae and if known their chromosome number and full sectional and subsectional classification in Veronica is provided. For this purpose three new combinations have been introduced (Veronica Seet. Acinifolia (Rompp) Albach. Veronica Seet. Glandulosae (Rompp) Albach, and Veronica subsect Cochlidiosperma (Rchb.) Albach).
Lead Concentrations of Herbs Used in Van Herby Cheese
(Natural Product Incorporation, 2011) Tuncturk, M.; Tuncturk, R.; Sekeroglu, N.; Ertus, M.; Ozgokce, F.
Van Herby Cheese is a traditional milk product including local herb species in eastern Turkey. This special milk product was previously produced only for the local market, but industrial scale production and marketing have recently started in the region. However, some quality characteristics such as microbial flora and heavy metal concentrations of this novel product need to be investigated. In this study, lead concentrations of 28 different herbs mostly used in Van Herby Cheese were analyzed by AAS. The highest lead concentration of 1.69 mg kg-1 of the analyzed herbs was found in Mentha longifolia (L.) Hudson subsp. longifolia.
New Cycloartane-Type Glycosides From Astragalus Icmadophilus Hand.-Mazz
(Georg Thieme verlag Kg, 2009) Horo, I; Bedir, E.; Perrone, A.; Piacente, S.; Ozgokce, F.; Alankus-Caliskan, O.