Browsing by Author "Ozgokce, Fevzi"

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An Aeropalynological Survey in the City of Van, a High Altitudinal Region, East Anatolia-Turkey
(Springer, 2017) Bicakci, Adem; Tosunoglu, Aycan; Altunoglu, Mustafa Kemal; Saatcioglu, Gulsah; Keser, Ali Murat; Ozgokce, Fevzi
Pollen concentrations in the atmosphere of Van city has been monitored for two consecutive years (2010-2011). This was the first detailed aeropalynological study for the elevated East Anatolia Region of Turkey. The sampling was performed by Hirst-type volumetric sampler, and pollen grains of 35 taxa were identified. The main pollen producers of the pollen flora were recorded as: Poaceae (20.94 %), Cupressaceae (10.53 %), Fraxinus (8.56 %), Chenopodiaceae/Amaranthaceae (7.77 %), Populus (7.75 %), Quercus (6.70 %), Platanus (6.68 %), Morus (5.57 %), Plantago (3.03 %). The pollen spectrum reflected the floristic diversity of the region, and the highest pollen concentration was recorded in April. There were a great percentage of allergenic taxa found in the city atmosphere, otherwise many of them scored under threshold values for risk of pollinosis. Statistical analyses were performed for correlating daily pollen concentrations of dominated pollen types concurrent with the data of meteorological parameters in MPS periods and number of significant correlations found. In addition, comparing 2-year data in terms of pollen concentrations and meteorological factors in MPS durations, many variables were found explanatory and concordant with the data. MPS starting dates of many plant taxa were found nearly a month later compared with western sites and lower altitudes of the country as well as Mediterranean countries; this case is mostly thought the ecological factors of the study area which directly affects the plant growth about the timing.
Analysis of Taxonomic and Geographic Patterns of Turkish Veronica Orientalis Using Nuclear and Plastid Dna and Morphological Data
(Springer Wien, 2014) Sonibare, Mubo A.; Armagan, Metin; Ozgokce, Fevzi; Yaprak, Ahmet Emre; Mayland Quellhorst, Eike; Albach, Dirk C.
Veronica orientalis and related species form one of the taxonomically most challenging subgroups within the genus Veronica. Hybridization and polyploidization on the one hand and convergent character evolution on the other have made delimitation of species difficult. Amplified fragment length polymorphisms and plastid DNA markers were used in conjunction with 54 morphological characters to study relationships among 35 accessions of V. orientalis Mill. as well as other closely related species of Veronica occurring in Turkey and adjacent areas of Georgia and Armenia. In addition, ploidy levels were estimated for 15 accessions using flow cytometry. Diploid to hexaploid individuals were detected in V. orientalis. Analysis of DNA markers demonstrated the non-monophyly of V. orientalis, especially with regard to V. fuhsii and V. multifida from Eastern Turkey, but nuclear and plastid DNA markers are largely incongruent. Neither demonstrates a clear biogeographic pattern. The morphological analysis reveals the distinction of V. orientalis subsp. carduchorum, which is weakly retrieved in some molecular analyses and some clustering according to geography. V. multifida is not monophyletic likely due to parallel evolution of pinnatifid leaves east and west of the Anatolian diagonal.
Anti-Alzheimer, Antiglaucoma, and Antidiabetic Activities of Sainfoin (Onobrychis Buhseana Boiss.)
(Wiley-v C H verlag Gmbh, 2025) Jafarova, Shahla; Aydin, Tuba; Isayev, Javanshir; Saglamtas, Ruya; Ozgokce, Fevzi; Kazaz, Cavit; Cakir, Ahmet
Onobrychis Adans. species, known as 'sainfoin,' are commercially valuable plants cultivated to produce high-protein animal feed. In this study, the ethanol extract of Onobrychis buhseana Boiss., which is widely distributed in Azerbaijan, was subjected to silica gel column and thin-layer chromatography for the first time, leading to the isolation of a new natural hydroquinone oligomer, named buhseanol (1), along with two known compounds, beta-arbutin (2) and an inositol derivative (3). The chemical structure of buhseanol (1) was characterized by proton nuclear magnetic resonance (1H-NMR), carbon-13 NMR, Attached Proton Test NMR, and liquid chromatography-tandem mass spectrometry. Buhseanol (1), beta-arbutin (2), and the ethanol extract were evaluated for their anti-Alzheimer's, anti-glaucoma, and anti-diabetic effects, with both the extract and buhseanol (1) potentially showing these activities. The inositol derivative (3) did not exhibit any of these activities.
Antibacterial Activities of Allium Vineale, Chaerophyllum Macropodum and Prangos Ferulacea
(Academic Journals, 2006) Durmaz, Hisamettin; Sagun, Emrullah; Tarakci, Zekai; Ozgokce, Fevzi
Allium vineale L., Chaerophyllum macropodum Boiss. and Prangos ferulacea (L.) Lindl. have been used for cheese production in Turkiye for many centuries. In addition, it is traditionally believed by local people that these plants have antibacterial activity. The purpose of this study was to evaluate the antibacterial activity of these plants. Four solvent extracts (in methanol, ethanol, n-hexane and water) of the plants were investigated against Bacillus cereus, Bacillus subtilis, Micrococcus luteus, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella enteritidis and Salmonella typhimurium by using disc diffusion method. The methanol, ethanol and n-hexane extracts of all the plants showed antibacterial activity against B. cereus, B. subtilis, M. luteus and S. aureus, while the methanol extract of Allium vineale was also active against P. mirabilis. However, the water extracts of these plants had no antibacterial activity against any of the bacteria tested. The methanol extracts had the higher activity followed by the extracts of ethanol and n-hexane. A. vineale showed the higher antibacterial activity as compared with C. macropodum and P. ferulacea. As a result, organic solvent extracts (especially methanol and ethanol extracts) of these plants can be used as natural antibacterial additives for incorporation in cheese and various food products.
Antioxidant Activity of Aqueous and Ethanol Extracts of Crataegus Meyeri Pojark Leaves and Contents of Vitamin, Trace Element
(Soc Chilena Quimica, 2017) Ekin, Suat; Bayramoglu, Mahire; Goktasoglu, Ahmet; Ozgokce, Fevzi; Kiziltas, Hatice
The purpose of this study was to determine the antioxidant and antiradical activities in aqueous and ethanol extracts of Crataegus meyeri Pojark leaf, additionally, to examine some vitamins (A, E, C), trace elements (Cu, Zn, Mn, Se, Cr. Co). In this study, vitamin C, antioxidant and antiradical properties were determined using spectrophotometer. The results are compared with the reference antioxidants such as trolox, alpha-tocopherol and BHT. Levels of vitamin (A, E) measured using HPLC method. Trace elements were carried out using method of dry ashing with ICP-MS. The results of this study showed that C. meyeri leaf has a high antioxidant capacity and vitamin levels. C. meyeri is thought to be used as additives for food products and pharmaceutical industries with appropriate antioxidant properties and an antioxidant in future studies of experimental animal models, against free radicals generated in response to oxidative stress.
Antioxidant and Anticholinesterase Constituents of Salvia Poculata
(Tubitak Scientific & Technological Research Council Turkey, 2009) Kolak, Ufuk; Hacibekiroglu, Isil; Ozturk, Mehmet; Ozgokce, Fevzi; Topcu, Guelacti; Ulubelen, Ayhan
Two triterpenoids, namely 2 alpha,3 alpha-dihydroxy-24-nor-4(23), 12-oleanadien-28-oic acid (1) and ursolic acid (2); 4. avonoids, namely 5-hydroxy-7,4'-dimethoxyflavone (3), cirsimaritin (4), eupatilin (5), and salvigenin (6); a diterpenoid, namely sclareol (7); and a steroid, namely beta-sitosterol (8), were isolated from the aerial parts of Salvia poculata Nab., a Turkish endemic Salvia species. Total phenolic and flavonoid contents of the crude extract were determined as pyrocatechol and quercetin equivalents, respectively. The antioxidant activity of the crude extract and the isolated compounds (2-8) was established using beta-carotene bleaching, superoxide anion radical, and ABTS cation radical scavenging activity. In addition, the anticholinesterase activity of the crude extract and the isolated compounds (2-8) against the enzymes acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) was determined. The phytochemistry and antioxidant and anticholinesterase activities of S. poculata were investigated for the first time in this study. The crude extract of S. poculata exhibited a significant antioxidant effect as well as butyrylcholinesterase inhibitory activity. Ursolic acid (2) and cirsimaritin (4) possessed high butyrylcholinesterase inhibitory activity.
Antioxidant Properties of Ferulago Angulata and Its Hepatoprotective Effect Against N-Nitrosodimethylamine Oxidative Stress in Rats
(Taylor & Francis Ltd, 2017) Kiziltas, Hatice; Ekin, Suat; Bayramoglu, Mahire; Akbas, Esvet; Oto, Gokhan; Yildirim, Serkan; Ozgokce, Fevzi
Context: Ferulago angulata (Schlecht.) Boiss. (Apiaceae) (FASB) is used to treat liver diseases and has been used both as food and therapeutics by many cultures for thousands of years because of the natural antioxidant compounds. Objective: This study determines antioxidant properties of FASB flowers, the levels of minerals and vitamins, and also, evaluates the hepatoprotective effect of flowers against N-nitrosodimethylamine (NDMA) induced on liver tissue by assessing antioxidant enzymes and histopathological parameters in Wistar albino rats. Materials and methods: In the study, the rats were divided into six groups of ten. Control, untreated animals were given 0.9% NaCl. Rats were intraperitoneally given NDMA (10 mg/kg) for the first 7 days. FASB methanol extract (150 and 300 mg/kg) was administered orally for 21 days. Results: a-Tocopherol, retinol, ascorbic acid, total antioxidant activity, phenolic and flavonoid contents of FASB were 0.70 +/- 0.13, 0.29 +/- 0.03 mu g/g, 139.32 +/- 7.06 mu g/100 g, 171.61 +/- 6.05 mM ascorbic acid/g, 90.47 +/- 4.11 mg GA/g and 37.39 +/- 2.85 mg QE/g. DPPH and hydroxyl radical scavenging activity was obtained IC 50 67.34 +/- 4.14 and 64.87 +/- 4.68 mu g/mL, respectively. Discussion and conclusion: The results of the study indicated that FASB flowers contain high levels of vitamins, minerals, total antioxidant activity, phenolics and flavonoids. Due to the positive effect on significant changes in antioxidant enzymes of liver tissue and histopathological examination, it is thought that the plant could be used as a hepatoprotective.
Antioxidant Properties of Rosa Pisiformis and Its Protective Effect Against Isoproterenol-Induced Oxidative Stress in Rats
(Walter de Gruyter Gmbh, 2016) Bayramoglu, Mahire; Ekin, Suat; Kiziltas, Hatice; Oto, Gokhan; Susen, Ebru Altindal; Ozgokce, Fevzi
Objective: In this study, Rosa pisiformis was evaluated for its antioxidant activity, vitamin (A, E, C), trace element (Fe, Cu, Zn, Mn, Cr, Se) and mineral (Ca, K, Mg, Na) levels, in addition to its cardioprotective effects on cardiac tissue antioxidant enzymes (GSH-Px, SOD, CAT) during isoproterenol (ISO)-induced oxidative stress. Methods: In the study, vitamin and mineral analysis was carried out using HPLC and ICP-MS method, R. P. antioxidant and antiradical properties were determined using spectrophotometer. Forty wistar albino rats were divided into four groups: control (0.9% NaCl), ISO (100 mg/kg), ISO (100 mg/kg) + R. P. (300 mg/kg) and R. P. (300 mg/kg). ISO was injected subcutaneously into rats twice at an interval of 24 h for two consecutive days (on 28(th) and 29(th) day). R. P. fruit administered daily. The experimental period was continued for 30 days. Results: The results of the study indicated that R. P. fruit and leaves contain high levels of minerals and vitamins and possess antioxidant and antiradical activity and its fruits have positive effects on cardiac tissues. The results are supported with significant changes in antioxidant enzyme levels and histopathological examination. Conclusion: This study demonstrates that R. P. fruits in particular can be used to treat and prevent cardiac diseases.
Chemical Composition of Some Apiaceae Plants Commonly Used in Herby Cheese in Eastern Anatolia
(Tubitak Scientific & Technological Research Council Turkey, 2015) Tuncturk, Murat; Ozgokce, Fevzi
Traditional uses of wild edible plants in daily diets are common in Eastern Anatolia. It is well known that more than 40 different plant species have been used as fresh vegetable, dried herbs, and pickled plants in some sole or mixed milk and meat products. The major use of wild edible plants is Van herby cheese in this region. To date, the mineral compositions of wild edible plants used in Van herby cheese production have been studied individually. In the present study, the plants were grouped by their plant families and their mineral compositions were determined. Therefore, variations and relations of minerals among the plants belonging to the same family were evaluated. The most used and well-known Apiaceae members such as Anethum graveolens L., Anthriscus sp., Chaerophyllum macropodum, F. haussknechtii H. Wolff ex Rech. f., Ferula rigidula DC., Heracleum persicum, Hippomarathrum microcarpum, Pimpinella aurea DC, and Prangos ferulacea L. were analyzed for their macro-and microelement concentrations (Ca, Co, Cu, Cr, Fe, K, Mn, Mg, N, Na, P, S, and Zn). Additionally, some food quality aspects (e.g., dry matter, total ash contents, crude protein contents, pH, and crude fiber contents) were also evaluated in the plant samples. In conclusion, plant samples analyzed had impressive diversity for mineral compositions and other properties. It can be concluded that these plentiful variations among plants belonging to the same family could have resulted from individual genetic structure, different growing conditions, and plants parts.
Cycloartane Glycosides From Astragalus Aureus
(Pergamon-elsevier Science Ltd, 2011) Gulcemal, Derya; Alankus-Caliskan, Ozgen; Perrone, Angela; Ozgokce, Fevzi; Piacente, Sonia; Bedir, Erdal
Eight cycloartane-type triterpene glycosides (1-8) were isolated from Astragalus aureus Willd along with ten known cycloartane-type glycosides (9-18). Their structures were established by the extensive use of 1D and 2D-NMR experiments along with ESIMS and HRMS analyses. Compounds 1-5 are cyclocanthogenin glycosides, whereas compounds 6-8 are based on cyclocephalogenin as aglycon, more unusual in the plant kingdom, so far reported only from Astragalus spp. Moreover, for the first time monoglycosides of cyclocanthogenin (5) and cyclocephalogenin (7, 8) are reported. All of the compounds tested for their cytotoxic activities against a number of cancer cell lines. Among the compounds, only 8 exhibited activity versus human breast cancer (MCF7) at 45 mu M concentration. (C) 2011 Elsevier Ltd. All rights reserved.
Datura Stramonium Intoxication: Report of a Case With Psychiatric Symptoms
(Yerkure Tanitim & Yayincilik Hizmetleri A S, 2011) Karadas, Sevdegul; Selvi, Yavuz; Sahin, Mustafa; Selvi, Fatih; Oncu, Resit; Ozgokce, Fevzi
Delirium is a common neuropsychiatric syndrome and is often caused by metabolic, systemic disorders and drug or poison intoxication. Though hallucinations, delusions and agitation are sometimes present, the symptoms of delirium are clinically distinct from those induced by other psychiatric disorders. Datura stramonium is a hallucinogenic plant which is a member of belladona alkaloids. The toxic effects of Datura stramonium most often include visual and auditory hallucinations, confusion and agitation. We report a patient who was poisoned with Datura stramonium and presented to the emergency department with psychiatric symptoms.
Effects of Leontice Leontopetalum and Bongardia Chrysogonum Extracts on Pentylenetetrazole Kindling Epilepsy Modelin Rats
(Wiley-blackwell, 2016) Erkec, Ozlem Ergul; Arihan, Okan; Bulut, Gulay; Karatas, Ersin; Meral, Ismail; Ozgokce, Fevzi
Effects of Leontice Leontopetalum and Bongardia Chrysogonum on Oxidative Stress and Neuroprotection in Ptz Kindling Epilepsy in Rats
(C M B Assoc, 2018) Erkec, Ozlem Ergul; Arihan, Okan; Kara, Mehmet; Karatas, Ersin; Erten, Remzi; Demir, Halit; Ozgokce, Fevzi
We investigated the effects of Leontice leontopetalum and Bongardia chrysogonum on apoptosis, gamma-aminobutyric acid (GABA(A)) receptor positive cell number. cyclin-B1 and bcl-2 levels and oxidative stress in pentylenetetrazol (PTZ.) kindling in rats. Kindling was produced by subconvulsant doses of PTZ treatments in rats. Wistar albino rats were divided into 4 groups; Control, PTZ treated (PTZ), PTZ ;L. leontopetalum extract treated (PTZ FILE) and PTZ ;B. chrysogonum extract treated (PTZ+BCE) groups. Extracts were given a dose (200 mg/kg) 2h before each PTZ, injection. PTZ treatment significantly decreased the glutathione peroxidase (GSH-Px), superoxide dismutase (SOD) activities and bc1-2 levels and increased the total oxidant status (TOS), malondialdehyde (MDA), cyclin B1, oxidative stress index (OSI) and number of neurons that expressed GABA(A) receptors when compared to the control. LLE and BCE possessed antioxidant activity in the brain and ameliorated PTZ induced oxidative stress, decreased cyclin-B1, increased bcl-2 levels, and kept the GABA(A) receptor number similar to that of the control despite the PTZ application.
Effects of Rheum Ribes Ethanolic Extracts on Cytochromes P450 1b1 (Cyp1b1) Gene Expression and Glutathione-S (Gst) Activity in Hl-60 Cells
(Taylor & Francis inc, 2008) Uyar, Pembegul; Ozgokce, Fevzi; Coruh, Nusen; Iscan, Mesude
Ethnobotanical and Pharmacological Uses of Some Plants in the Districts of Karpuzalan and Adiguzel (van-Turkey)
(Medwell online, 2008) Yildirim, Bunyamin; Terzioglu, Oemer; Ozgokce, Fevzi; Turkozu, Didem
This study has been carried out in Karpuzalan and Adiguzel districts of Van province between the years 2006 and 2007. At the beginning, questionnaires have been conducted in order to learn what kind of plants is used for which purpose by the villagers. After this, these plants have been collected from the fields and identified in Yuzuncu Yil University, Faculty of Science and Letters, Department of Biology and they have been included in herbarium. Later, the villagers defined which of them are consumed for nutritional purposes; which of them are used in herby cheese consumed in the region widespreadly; which of them are used for medical purposes. As a result, the present paper presents new original plants used for drug industry on medical purposes (animal and human health).
Fruit and Seed Morphology of Six Species Previously Placed in Malcolmia (Brassicaceae) in Turkey and Their Taxonomic Value
(Tubitak Scientific & Technological Research Council Turkey, 2011) Kaya, Ayla; Unal, Murat; Ozgokce, Fevzi; Dogan, Bekir; Martin, Esra
The fruit and seed morphologies of 6 species previously placed in the genus Malcolmia W.T.Aiton were examined with stereomicroscopy and scanning electron microscopy (SEM) in order to determine the significance of fruit and seed features as taxonomic characters. This study presents macro- and micromorphological characters, including fruit and seed shape, size, colour, fruiting pedicel size, fruit hair and density, seed coat pattern, epidermal cell shape, and anticlinal and periclinal cell walls. The results showed that the morphological characteristics of the fruit and seed could be used as criteria to distinguish genera and tribes. The investigated features of specimens indicated that Malcolmia chia (L.) DC. and M.flexuosa (Sikh. & Sm.) Sibth. & Sm. should remain in the genus that belongs to the tribe Anastaticeae. Malcolmia crenulata (DC.) Boiss. and M. exacoides (DC.) Spreng. belong to the genus Zuvanda (Dvorak) Askerova of the tribe Conringieae. Finally, Malcolmia africana (L.) W.T.Aiton and M. intermedia C.A.Mey. belong to the genus Strigosella Boiss. of the tribe Euclidieae. A key is provided for the identification of the investigated species based on fruit and seed characters.
Investigation of Some Chemical Characteristics of Wild Edible Cephalaria Schrader Ex Roemer & Schultes Gc Setosa Boiss & Hohen Grooving in East Anatolia
(Assoc Pharmaceutical Teachers india, 2017) Tuncturk, Ruveyde; Tuncturk, Murat; Eryigit, Tamer; Ozgokce, Fevzi
Nutritional value and mineral compositions of wild edible plants have been investigated for food security and human health. It is though that wild edible plants gathered from nature are cheaper food and important for human health. They are also special ingredients for distinguished taste and aroma of traditional cousins. Thus, in the present study the nutritional value and mineral composition of used parts of Cephalaria schrader was investigated. In laboratory analysis, dry matter, total ash, % N, crude protein, crude fiber and pH were examined as nutritional value. Useful minerals (Ca, Cu, Fe, K, Mg, Mn, Na, P, S and Zn) and heavy metals (Cd, Co, Cr and Pb) that hazardous elements for livings were also determined by Atomic Absorption spectrometry (AAS). The Dry matter, pH, ash and total nitrogen content of the plants identified as 8.22%, 6.33%, 6.3% and 1.77%, respectively. Mineral analysis showed that the wild plants' samples contained considerably high amounts of potassium (12.31 g kg(-1)), phosphorus (1.14 g kg(-1)), calcium (9.67 g kg(-1)), magnesium (1.97 g kg(-1)), iron (146.23 mg kg(-1)), manganese (24.25 mg kg(-1)) and zinc (18.70 mg kg(-1)). This work contributed to the nutritional properties of some wild plants, and the results may be useful for the evaluation of dietary information.
Investigation of the Effects of Physico-Chemical Environmental Conditions on Population Fluctuations of Notonecta Viridis Delcourt, 1909 (Hemiptera: Notonectidae) in Van Lake by Using Zero-Inflated Generalized Poisson Regression
(Entomological Soc Turkey, Ege Univ, 2011) Yesilova, Abdullah; Ozgokce, Mehmet Salih; Atlihan, Remzi; Karaca, Ismail; Ozgokce, Fevzi; Yildiz, Sukran; Kaya, Yilmaz
In ecological studies, it is a common situation occured that population density of species extremly increases or decreases in certain periods depending on many abiotic and biotic factors. Because of ecologial factors that cause high level fluctuation in population density, It is possible to get zero individual at samplings, and on the other hand, differences between maximum and minimum values obtained in different samplings intervals can be very high. Because this type of data based on counting does not show normal distribution, and shape of the distribution is skewed to the right because of the abundance of zero, using the Zero-inflated Poisson regression method (ZIGP) is required. This study was carried out to obtain information on effects of physico-chemical environmental conditions on population fluctuation of Notonecta viridis. Samplings were conducted with monthly periods along the coastal band of Van Lake in 2005-2006. Samples were taken from 20 sampling places where have three different characters as stream entrances, settlements and natural coastlines. Reults were analysed by using ZIGP regression model. According to results, Effect of sampling intervals and sampling stations on population densities of Notonecta viridis were important. On the other hand, HCO3 had negative effect on population densities in zero-inflated model while it had possitive effect on population densities in other two models. It was determined that Fe effected the species populations in the negative way in the mean regression model, and Cl and Mg effected it in possitive way in the overdispersion regression. In the result, it was deductived that Notonecta viridis was found excessive numbers or none in some sampling stations because of the pysico-chemical structures of water.
Isatis Glauca Aucher Ex Boiss. Subsp. Glauca (Indigo) Extracts as Enzyme Inhibitors: a Biochemical Study
(Wiley-v C H verlag Gmbh, 2025) Nezir, Beyza Sevdenur; Dasdemir, Edanur; Aydin, Tuba; Saglamtas, Ruya; Kaya, Elife; Ozgokce, Fevzi
Isatis glauca Aucher ex Boiss. subsp. glauca is a species of indigo that grows naturally in T & uuml;rkiye. In this study, the in vitro biological activities of I. glauca were evaluated for the first time. The inhibitory effects of I. glauca's methanol, ethanol, dichloromethane/methanol (50:50), acetone, ethyl acetate, dichloromethane, and n-hexane extracts were investigated on the enzymes human carbonic anhydrase I (hCAI), human carbonic anhydrase II (hCAII), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and alpha-glycosidase. IC50 values were calculated to determine the inhibitory effect of the extracts. Among the extracts, the ones with the strongest inhibitory activity against hCAI, hCAII, AChE, BChE, and alpha-glucosidase were found to be ethyl acetate extract (IC50: 75.77 mg/mL), methanol extract (IC50: 102.89 mg/mL), n-hexane extract (IC50: 61.11 mg/mL), ethyl acetate extract (IC50: 22.79 mg/mL), and ethyl acetate extract (IC50: 77.12 mg/mL), respectively. The study findings suggest that all extracts of I. glauca may have promising therapeutic properties. In particular, it can be suggested that these extracts have the potential to be used in the treatment of diseases or the alleviation of symptoms. However, additional research and clinical trials are required to determine its efficacy. The isolation of I. glauca phytochemicals should be addressed in future studies.
Microwave-Assisted Extraction of Polyphenolics From Some Selected Medicinal Herbs Grown in Turkey
(Acg Publications, 2018) Baki, Sefa; Tufan, Ayse Nur; Altun, Mehmet; Ozgokce, Fevzi; Guclu, Kubilay; Ozyurek, Mustafa
The effect of microwave-assisted extraction (MAE) process on the antioxidant capacity/activity of three medicinal herbs from Turkey was investigated by electrochemical differential pulse voltammetric (DPV)CUPric Reducing Antioxidant Capacity (CUPRAC) assay. The optimal extraction time, temperature and solvent type were 6 min, 80 degrees C and 80% (v/v) methanol (MeOH), respectively. Microwave-assisted extracts of herbs (Hypericum scabrum L., Papaver fugax Poiret var. platydiscus Cullen, and Achillea vermicularis Trin.) were screened for total antioxidant capacity (TAC), total phenolic content (TPC) and ROS scavenging activities by employing different in vitro spectrophotometric assays. A positive correlation was observed between TACCUPRAC and TPC (R-2 = 0.972). Similarly, a positive correlation was observed between TAC-CUPRAC and free radical scavenging (FRS) activity (R-2 = 0.977). The order of FRS activities of tested samples was as follows: Hypericum scabrum L. > Achillea vermicularis Trin. > Papaver fugax Poiret var. platydiscus Cullen. These results suggest that these medicinal herbs provide promising antioxidant potentials as potential natural preservative agents in pharmaceutical industries.