Browsing by Author "Ozkacmaz, Sercan"

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Aneurysmal Dilatation of Vein of Galen Associated With Thalamic Arteriovenous Malformation and Straight Sinus Agenesis
(Wolters Kluwer Medknow Publications, 2023) Ozkacmaz, Sercan
Straight sinus agenesis is a rare congenital anatomical variation that is usually accompanied by persistent falcine sinus. Concomitance of straight sinus agenesis and absence of falcine sinus are associated with thalamic arteriovenous malformation by the disturbance of the venous flow. In this report, a very rare case of aneurysmal dilatation of the vein of Galen associated with thalamic arteriovenous malformation and straight sinus agenesis is presented.
Assessment of Optic Nerve Vascularity in Healthy Eyes Using Superb Microvascular Imaging: a Preliminary Study
(Sage Publications Ltd, 2022) Batur, Abdussamet; Alpaslan, Muhammed; Ozkacmaz, Sercan; Durmaz, M. Sedat
Background Changes in optic nerve vascularity are observed in many diseases. Superb microvascular imaging (SMI) has the potential to become the method of choice for detecting microvasculature in the optic nerves. Purpose To evaluate optic nerve vascularity in healthy individuals through power Doppler sonography (PDUS) and SMI. Material and Methods Twenty-seven healthy patients with 54 eyes were prospectively evaluated. The duration of the examination for optic nerve vascularity lasted until the posterior ciliary artery blood supply was observed in PDUS and SMI. The visibility of vascularity, as well as the ratio of the vascular structures to the optic nerves (vascular index [VI]), was evaluated. Results Fifty-four eyes were evaluated from a total of 27 patients (mean age = 49.0 +/- 19.42 years). The VI value for the right optic nerve was 29.58 +/- 4.00 while for the left optic nerve, it was 31.21 +/- 3.52. Vascularity was clearly observed in both eyes (n = 54) in all 27 cases in the evaluation performed with the SMI technique. However, with the power Doppler examination, vascular flow was not observed in 14 right eyes and in 10 left eyes within the specified timeframe. Conclusion The results indicate that imaging of vascular structures can be done faster and better with SMI than PDUS examination. The normal VI values may provide important information about the blood supply of the optic nerve, which is of relevance in orbital pathologies and many systemic conditions.
Association of Chiari Type 1 Malformation and Cervical Spine Curve Changes
(Wolters Kluwer Medknow Publications, 2021) Alpaslan, Muhammed; Ozkacmaz, Sercan; Dadali, Yeliz; Ucar, Ilyas
Introduction: In this study, we aimed to examine the association of cervical spine curve abnormalities (loss of cervical lordosis or reversal of cervical curve) with Chiari Type 1 malformation (CM1). Further, a possible relation of syrinx formation in the cervical spinal cord and disc protrusion with CM1 was analyzed. Material and Methods: Cervical spinal magnetic resonance imagings of 998 patients were retrospectively screened for the presence of CM1. The frequency rates of syrinx formation within the spinal cord, cervical spinal curve changes, and cervical disc herniation among CM1+ and CM1- patients were compared. Results: Patients with CM1 have significantly higher rate of loss of cervical lordosis when compared with those who have not CM1. The syrinx formation rate was also found lower in the CM1+ patients with loss of cervical lordosis than in CM1+ patients with either normal cervical lordosis or reversed cervical curve. No significant difference was detected between CM1+ and CM1- patients regarding cervical disc herniation rate. Discussion and Conclusion: As the loss of cervical lordosis rate is higher in CM1, the patients with lateral X-ray findings of cervical lordosis flattening may be evaluated regarding typical neurological symptoms of syringomyelia.
The Association of Vascular Loops of Anterior Inferior Cerebellar Artery and Vestibulocochlear Symptoms
(Wolters Kluwer Medknow Publications, 2023) Dadali, Yeliz; Ozkacmaz, Sercan; Avcu, Mustafa; Alpaslan, Muhammed; Goya, Cemil; Ozgokce, Mesut; Durmaz, Fatma
Aim: The association of vascular loops of anterior inferior cerebellar artery (AICA) with vestibulocochlear symptoms including hear loss, tinnitus, and vertigo is controversial. We aimed to investigate the relationship between vestibulocochlear symptoms and AICA vascular loop syndrome on magnetic resonance imaging (MRI). Materials and Methods: The patients underwent a posterior fossa MRI examination were reviewed regarding the presence of hear loss, tinnitus, and vertigo by an experienced ear-nose-throat specialists' physical examinations. The incidences of these lesions in the patients with and without AICA vascular loop syndromes were compared. Furthermore, the correlation between the AICA vascular loop syndrome subtypes (grade 1-3) and the incidence of the symptoms were analyzed. Results: A total of 502 patients (1004 ears) were included in this study. Vascular loops were demonstrated in 150 ears (14.9%). Subtype 1 was observed in 97 (9.7%), subtype 2 in 40 (4.0%) and subtype 3 in 13 (1.3%) ears. The incidences of tinnitus, hear loss, and tinnitus + hear loss were statistically significantly higher in the patients with vascular loops than without vascular loops (p: 0.000042, p: 0.0446906, p: 0.028106, respectively). However, there was not a significant correlation between the incidence of the symptoms and the grade of the vascular loop formation (p>0.05). Vertigo incidence was very similar among the patients with no, with one-sided and with both-sided AICA vascular loops (41.5%, 39.8% and 46.2%, respectively) with no statistical difference (p>0.05). Conclusion: The AICA vascular loop is associated with either tinnitus or hear loss but there is no correlation with the degree of the vascular loops. There is no relationship between AICA vascular loops and vertigo.
Chiari Iii Malformation With a Giant Encephalocele Sac: Case Report and a Review of the Literature
(Karger, 2013) Bulut, Mehmet Deniz; Yavuz, Alpaslan; Bora, Aydin; Gulsen, Ismail; Ozkacmaz, Sercan; Sosuncu, Enver
Clinical Impacts of Juxtapapillary Duodenal Diverticulum Detected on Computed Tomography
(Bentham Science Publ Ltd, 2022) Dundar, Ilyas; Goya, Cemil; Hattapoglu, Salih; Ozkacmaz, Sercan; Ozgokce, Mesut; Turkoglu, Saim; Turko, Ensar
Background: Diverticula are commonly observed in the duodenum. Duodenal Diverticulum (DD) usually does not give symptoms throughout life and is diagnosed by coincidence. However, it may present with different symptoms in patients. Objective: This study aims to evaluate the prevalence of DD and Juxtapapillary Duodenal Diverticilium (JDD) and its association with other possible pathologies and to determine its clinical impact by using Computed Tomography (CT). Methods: This retrospective observational study, which was taken consecutively between the years of 2013-2020, was evaluated in the Radiology Department. The total number of cases was 4850 (male-2440; female-2410). CT images were evaluated by two experienced radiologists at the workstation. DD and JDD prevalence and clinical findings in the hospital registry system were examined. Results: The age of the patients included in the study ranged from 17 to 92 years (mean age 46.94 +/- 16.42). In patients with DD (female-130; male-101), mean age was 62.24 +/- 12.69 (21-92). The prevalence of DD was 4.76% (n=231). The prevalence of JDD was 4.02% (n=195) and increased with age (p<0.01). The average diameter of the JDD was measured as 23.29 +/- 8.22 (9.5-55.3) mm. A significant positive correlation was found between age and DD diameter (p=0.039). DDs were found most commonly 84.42% (n=195) in the second segment of the duodenum as JDD. In patients with JDD, the mean diameter of choledochus and wirsung canal were 6.7 +/- 2.4 (3-15.3) mm and 0.31 +/- 0.1 (0.1-6.5) mm respectively. The choledochal diameter was correlated with the JDD size (p - 0.004). Cholelithiasis (n 56), choledocholithiasis (n 20), cholecystitis (n=52), diverticulitis (n=15), duodenitis (n=37), pancreatitis (n=5) and hiatal hernia (n=60) with JDD were observed. Periampullary carcinoma was detected in one patient. Conclusion: Our study shows that cholelithiasis, choledocholithiasis, cholecystitis, diverticulitis, duodenitis, pancreatitis may be associated with JDD. Therefore, in contrast-enhanced abdominal CT scans taken for various reasons, investigation of the presence and characteristics of JDD and detection of pathologies that may be associated with JDD are important for patients to benefit from early diagnosis and treatment opportunities and to take precautions against possible complications.
Comparison of Computed Tomography Findings Between Adult and Pediatric Covid-19 Patients
(Bentham Science Publ Ltd, 2024) Dadali, Yeliz; Ozkacmaz, Sercan; Unlu, Erdal; Ozkacmaz, Ayse; Alparslan, Muhammed; Dundar, Ilyas; Goya, Cemil
Purpose: This study aims to compare chest computed tomography (CT) findings between adult and pediatric patients with coronavirus disease-19 (COVID-19) pneumonia. Materials and Methods: This study included 30 pediatric patients aged 1 to 17 years and 30 adult patients over 18 years of age with COVID-19 pneumonia confirmed by reverse transcriptase-polymerase chain reaction (RT-PCR) who have findings related to COVID-19 on Chest Computed Tomography. The CT findings of adult and pediatric patients were compared with a z-test. Results: Bilateral involvement (p:0.00056), involvement in all five lobes (p<0.00001), and central and peripheral involvement (p:0.01928) were significantly higher in the adult group compared to the pediatric group. In the pediatric group, the frequency of unilateral involvement (p:0.00056), involvement of solitary lobe (p:0.00132), and peripheral involvement (p: 0.01928) were significantly higher than in the adult group. The most common parenchymal finding in adults and pediatric patients was ground-glass opacities (100% and 83%, respectively). Among the parenchymal findings in adults, ground-glass opacities with consolidation (63%) were the second most common finding, followed by air bronchogram (60%) in adults, while in pediatric patients, halo sign (27%) and nodule (27%) were the second most common, followed by the ground-glass opacities with consolidation (23%). Conclusion: The CT findings of pediatric COVID-19 patients must be well-known as the course of the disease is usually less severe, and the radiological findings are uncertain when compared with adults.
Comparison of Medical Treatment Efficiency With Shear Wave Elastography Values of Thrombus in Patients With Lower Extremity Deep Vein Thrombosis
(Lippincott Williams & Wilkins, 2023) Ince, Suat; Ozgokce, Mesut; Ozkacmaz, Sercan; Dundar, Ilyas; Turko, Ensar; Ayyildiz, Veysel A.; Goya, Cemil
In lower-extremity deep vein thrombosis (DVT), thrombus age is essential for successful treatment. The aim of our study was to compare the shear wave elastography (SWE) values measured before treatment and achieved lumen patency after treatment in lower-extremity DVT patients with total occlusion. Patients diagnosed with DVT in the acute-subacute stage (<4 week) with total thrombosis in lower extremity were included in this prospective study. Shear wave elastography measurements were performed where the thrombus was most prominent and homogeneous. To evaluate patient response to treatment, lumen patency (partial [>25%] or total recanalization) was examined using color Doppler imaging in the first and third months posttreatment. Shear wave elastography values with and without patency were compared using an independent t test. Among 75 patients in this study, at the first-month color Doppler imaging examination, the SWE values were 1.77 +/- 0.49 (1.09-3.03) m/s in patients who achieved lumen patency (n = 42) and 2.21 +/- 0.54 (1.24-3.36) m/s in those who did not show lumen patency (n = 33). The difference between the groups' mean elastography value was statistically significant (P < 0.001). At the third-month examination, the SWE values were 1.76 +/- 0.46 (1.09-3.03) m/s in patients with lumen patency (n = 55) and 2.52 +/- 0.48 (1.74-3.36) in patients without lumen patency (n = 20). The difference between the 2 groups' mean elastography value was statistically significant (P < 0.001). We concluded that it is more difficult to achieve lumen patency in veins occluded by thrombus with higher elasto values, and endovascular interventional procedures should be considered during the initial treatment of high SWE value thrombosis.
Computed Tomography and Magnetic Resonance Imaging Findings of Primary Bladder Angiosarcoma: a Case Report
(Elsevier Science inc, 2014) Beyazal, Mehmet; Pirincci, Necip; Yavuz, Alpaslan; Ozkacmaz, Sercan; Bulut, Gulay
Primary bladder angiosarcomas are extremely rare but aggressive tumors. Due to the small number of cases (less than 30) reported to date, the information about natural tumor progression, optimal treatment procedure and prognosis are limited. Also, published reports of bladder angiosarcoma have not adequately featured imaging findings. Herein we report computed tomography and magnetic resonance imaging findings of a 20-year-old male with primary angiosarcoma of the bladder. (C) 2014 Elsevier Inc. All rights reserved.
Computed Tomography Findings of Covid-19 in Pediatric Patients
(Turkish J Pediatrics, 2022) Dadali, Yeliz; Ozkacmaz, Sercan; Unlu, Erdal; Akyol, Rukiye; Alparslan, Muhammed
Background. In this study, we aimed to evaluate the thorax Computed Tomography (CT) findings of pediatric patients diagnosed with coronavirus disease-19 (COVID-19) and to discuss these findings in light of the results of adult patients from the literature.Methods. The CT scans of pediatric patients (1-18 years old) with a diagnosis of COVID-19 by reverse transcriptase-polymerase chain reaction (RT-PCR) in our hospital between March 2020 and January 2021 were retrospectively reviewed. The scans were interpreted regarding the distribution and localization features, and involvement patterns including ground-glass opacity, consolidation, halo/reversed halo sign, interlobular septal thickening, air bronchograms and bronchiectasis. The frequencies of these findings in pediatric cases in our study were recorded.Results. A total of 95 patients with a mean age of 13 +/- 4.6 years were included in this study. Among them, 34 (36%) had lesions associated with COVID-19 on CT scans. Bilateral involvement was detected in 15 (44%) while unilateral in 19 (56%) patients. Eighteen (53%) patients had single lobe involvement. In 16 (47%) patients a solitary lesion was detected and in 18 (53%) multiple lesions were present. Ground-glass opacity appearance was observed in 28 (82%), consolidation in 9 (26%), and ground-glass opacity with consolidation in 8 (24%), halo sign in 9 (26%), reversed halo sign in 2 (6%), interlobular septal thickening (interstitial thickening) in 1 (3%) patients.Conclusions. As symptoms are relatively milder in children with COVID-19, CT findings are less extensive than in adults. It is essential to know the thorax CT findings that aid in the diagnosis and follow-up of the disease.
Deep Learning in Distinguishing Pulmonary Nodules as Benign and Malignant
(Baycinar Medical Publ-baycinar Tibbi Yayincilik, 2024) Akinci, Muhammed Bilal; Ozgokce, Mesut; Canayaz, Murat; Durmaz, Fatma; Ozkacmaz, Sercan; Dundar, Ilyas; Goya, Cemil
Background: Due to the high mortality of lung cancer, the aim was to find convolutional neural network models that can distinguish benign and malignant cases with high accuracy, which can help in early diagnosis with diagnostic imaging. Methods: Patients who underwent tomography in our clinic and who were found to have lung nodules were retrospectively screened between January 2015 and December 2020. The patients were divided into two groups: benign (n=68; 38 males, 30 females; mean age: 59 +/- 12.2 years; range, 27 to 81 years) and malignant (n=29; 19 males, 10 females; mean age: 65 +/- 10.4 years; range, 43 to 88 years). In addition, a control group (n=67; 38 males, 29 females; mean age: 56.9 +/- 14.1 years; range, 26 to 81 years) consisting of healthy patients with no pathology in their sections was formed. Deep neural networks were trained with 80% of the three-class dataset we created and tested with 20% of the data. After the training of deep neural networks, feature extraction was done for these networks. The features extracted from the dataset were classified by machine learning algorithms. Performance results were obtained using confusion matrix analysis. Results: After training deep neural networks, the highest accuracy rate of 80% was achieved with the AlexNET model among the models used. In the second stage results, obtained after feature extraction and using the classifier, the highest accuracy rate was achieved with the support vector machine classifier in the VGG19 model with 93.5%. In addition, increases in accuracy were noted in all models with the use of the support vector machine classifier. Conclusion: Differentiation of benign and malignant lung nodules using deep learning models and feature extraction will provide important advantages for early diagnosis in radiology practice. The results obtained in our study support this view.
Does Arfi Elastography Complement B-Mode Ultrasonography in the Radiological Diagnosis of Idiopathic Granulomatous Mastitis and Invasive Ductal Carcinoma
(Sage Publications Ltd, 2022) Toprak, Nursen; Toktas, Osman; Ince, Suat; Gunduz, Ali Mahir; Yokus, Adem; Akdeniz, Huseyin; Ozkacmaz, Sercan
Background Idiopathic granulomatous mastitis (IGM) is a chronic, unpleasant autoimmune inflammatory condition and is clinically and radiologically often confused with breast malignancy. Purpose To investigate the contributions of qualitative and quantitative aspects of acoustic radiation force impulse (ARFI) elastography to the differential diagnosis between IGM and invasive ductal carcinoma (IDC) in the breast. Material and Methods Ninety-four women with IDC and 39 with IGM were included in the study. Shear wave velocity (SWV) was calculated for all lesions using quantitative elastography. Next, each lesion's correspondence on qualitative elastographic images to those on the B-mode images was evaluated: pattern 1, no findings on elastography images; pattern 2, lesions that were bright inside; pattern 3, lesions that contained both bright and dark areas; and pattern 4, lesions that were dark inside. Pattern 4 was subdivided into 4a (dark area same size as lesion) and 4b (dark area larger than lesion size). Sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy were calculated. Results The mean SWV based on ARFI elastography was 3.78 +/- 1.26 m/s for IGM and 5.34 +/- 1.43 m/s for IDC lesions (P < 0.05). Based on qualitative ARFI elastography, IDC lesions were mostly classified as pattern 4b, while IGM lesions were mostly classified as pattern 1 or 2 (P = 0.01). Evaluation of both the qualitative and quantitative aspects of ARFI elastography yielded a sensitivity of 89% and specificity of 84%. Conclusion ARFI elastography may facilitate the differential diagnosis between IGM and IDC.
Does Contrast-Enhanced Computed Tomography Raise Awareness in the Diagnosis of the Invisible Side of Celiac Disease in Adults
(Springer, 2022) Goya, Cemil; Dundar, Ilyas; Ozgokce, Mesut; Turko, Ensar; Ozkacmaz, Sercan; Durmaz, Fatma; Hattapoglu, Salih
Purpose This study aimed to evaluate the diagnosis and determine major and minor criteria of celiac disease (CD) with the malabsorption patterns (MABP) in the small intestine and colon on computed tomography (CT) and additional CT findings. Methods This retrospective study was conducted with 116 patients diagnosed with CD, 14 CD patients recovering with treatment, and 35 control patients with non-CD. All patients had CT examinations and histopathological diagnoses. The sensitivity, specificity, PPV, NPV, and accuracy values of each CT finding defined in the literature were statistically evaluated. According to the patient and control groups, the numerical values of the findings and the sensitivity and specificity values were measured according to this cut-off value. The distribution of CT findings according to pathological Marsh data was evaluated in CD patients. Results Sensitivity and specificity were found to be higher in small bowel MABP findings, mesenteric hypervascularity, and increased SMV/aorta diameter. There was a numerically significant difference in MDCT findings between the control and pathological Marsh groups. In the ROC analysis performed in terms of the total numerical values of each MDCT finding observed between the groups, it was found that there were more than 7 MDCT findings, 100% sensitivity, and 92% specificity. The presence of four major and three minor criteria or three major and four minor criteria were considered significant. Conclusions Being aware of CT findings below the iceberg that may suggest CD in abdominal CT examinations performed in patients with atypical clinical and malabsorption findings or other nonspecific findings may prevent diagnostic delay and unnecessary procedures. [GRAPHICS] .
Efficacy of Shear Wave Elastography in Malignity Assessment of Thyroid Nodules With Atypia of Undetermined Significance and Comparison With Ti-Rads
(Bayrakol Medical Publisher, 2022) Durmaz, Fatma; Ozgokce, Mesut; Ozkacmaz, Sercan; Dundar, Ilyas; Alay, Murat; Goya, Cemil; Kotan, Mehmet Cetin
Aim: The aim of this study is to investigate the effectiveness of shear wave elastography (SWE) in the differentiation of benign-malignant thyroid nodules diagnosed with atypia of undetermined significance (AUS) and to compare with the American College of Radiology (ACR)-thyroid imaging reporting and data system (TIRADS). Material and Methods: This monocentric study comprised 52 patients (9 males; 43 females) who were diagnosed with AUS by thyroid FNAB. All patients included in the study had gray scale ultrasound (US) and SWE images. The mean SWE value was calculated for each nodule, and TIRADS scores were determined based on the US. The obtained data were compared based on the histopathological result in patients who had undergone surgical treatment, and based on the cytology result in patients followed-up by FNAB, for the differentiation of benign and malignant nodules. Results: Nineteen patients were found to have malignant nodules and 33 had benign nodules. The mean SWE was 2.89 +/- 0.51 (2.30-3.92) and 2.91 +/- 0.48 (2.16- 3.79) in the malignant and benign cases, respectively. The results of independent T-tests between the two groups were insignificant (p=0.89). TIRADS 2-3 (total 29 patients) nodules were considered possibly benign, and TIRADS 4-5 (total 23 patients) possibly malign, the sensitivity, specificity, positive predictive and negative predictive value of TIRADS were identified 100%, 87.9%, 82.6% and 100%, respectively, when compared with the pathology results. Discussion: There was no significant difference in SWE values in the differentiation of malignant-benign thyroid nodules with AUS. However, the ACR-TIRADS criteria still maintain their importance.
The Efficiency of Acoustic Radiation Force Impulse (Arfi) Elastography in the Differentiation of Renal Cell Carcinoma and Oncocytoma
(Bentham Science Publ Ltd, 2024) Ozgokce, Mesut; Dundar, Ilyas; Durmaz, Fatma; Ozkacmaz, Sercan; Kankilic, Nazim A.; Aslan, Rahmi; Akinci, M. Bilal
Purpose This study is to investigate the effectiveness of Acoustic Radiation Force Impulse (ARFI) elastography in differentiating radiologically similar renal cell carcinoma (RCC) and oncocytoma in solid masses of the kidney. Methods The patients with solid renal mass histopathological diagnosed after excision or tru-cat biopsy who underwent a preoperative ARFI elastography of the lesion during a 4-year period were included in this study. Preoperative shear wave velocity (SWV) values were measured in all the lesions. SWV results of RCCs and oncocytomas were compared by an independent t-test, and cut-off, sensitivity and specificity values were calculated. Results Forty-two of the 60 patients included in the study were men (70%) and, 18 were women (30%), and the mean age was 59.7 +/- 14 (27-94) years. Among 46 RCCs (76.6%), 23 and 14 oncocytomas, 5 (23.4%) were located in the right kidney (p:0.34722). Mean SWV values were found to be significantly higher in RCCs (2.87 +/- 0.74 (0.96-4.14) m/s) than oncocytomas (1.83 +/- 0.78 (0.80-3.76) m/s) (p <0.001). In the ROC analysis, a cut-off value of 2.29 m/s was found to havean 80.4% sensitivity and a 78.6% specificity for the discrimination of RCCs from oncocytomas. Conclusion ARFI elastography measurements may be useful in distinguishing RCC and oncocytomas that may have similar solid radiological imaging features.
The Efficiency of Diffusion-Weighted Magnetic Resonance Imaging in the Differentiation of Malign and Benign Cavitary Lung Lesions
(Lippincott Williams & Wilkins, 2023) Durmaz, Fatma; Ozgokce, Mesut; Aydin, Yener; Yildiz, Hanifi; Ozkacmaz, Sercan; Dundar, Ilyas; Goya, Cemil
Purpose:The present study investigates the diagnostic efficiency of apparent diffusion coefficient (ADC) values in differentiating between malignant and benign cavitary lesions on diffusion-weighted magnetic resonance imaging (DWI). Materials and Methods:This prospective study included 45 consecutive patients identified with a cavitary lung lesion with a wall thickness of >= 5 mm on thoracic computed tomography in our clinic between 2020 and 2022, and who underwent thoracic DWI within 1 week of their original computed tomography. ADC measurements were made on DWI by drawing a region of interest manually from the cavity wall, away from the lung parenchyma in the axial section where the lesion was best demonstrated. The patients were then classified into benign and malignant groups based on the pathology or clinico-radiologic follow-up. Results:The sample included 29 (64.4%) male and 16 (35.6%) female patients, with a mean age of 59.06 +/- 17.3 years. Included in the study were 1 patient with 3 and 3 patients with 2 cavitary lesions each, with a total for the sample of 50 cavitary lesions. There were 23 (46%) malignant and 27 (54%) benign cavitary lung lesions. The mean ADC value (x10(-3) mm(2)/s) of the malignant and benign cavitary lesions was 0.977 +/- 0.522 (0.511 to 2.872) and 1.383 +/- 0.370 (0.930 to 2.213), respectively. The findings were statistically significant using an independent samples t test (P=0.002). The mean wall thickness of the malignant and benign lesions was 12.47 +/- 5.51 mm (5 to 25 mm) and 10.11 +/- 4.65 mm (5 to 22 mm), respectively. Although malignant cavities had a higher mean wall thickness than benign cavities, the difference was statistically insignificant (P=0.104). Conclusion:A significant difference was identified between the ADC values measured in DWI of the malignant and benign cavitary lung lesions. DWI, a noninvasive and rapid imaging method, can provide useful information for the differential diagnosis of cavitary lesions and can minimize unnecessary biopsies.
Efficiency of Diffusion-Weighted Mri for Differentiating Radiologically Similar Simple and Type I Hydatid Cysts of the Liver
(Sage Publications Ltd, 2022) Dundar, Ilyas; Ozgokce, Mesut; Durmaz, Fatma; Ozkacmaz, Sercan; Turkoglu, Saim; Goya, Cemil
Background Determining the nature of purely cystic hepatic lesions is essential because different kinds have different follow-ups, treatment options, and complications. Purpose To explore the potential of apparent diffusion coefficient (ADC) values of diffusion-weighted imaging (DWI) for the differentiation of type I hydatid cysts (HC) and simple liver cysts (SLC), which have similar radiological appearances. Material and Methods This single-center prospective study was conducted during 2016-2019. Round, homogenous, anechoic liver cysts >1 cm were classified according to at least two years of imaging follow-up, radiological features, serology, as well as puncture aspiration injection reaspiration procedure and pathology results. ADC values of 95 cysts (50 type I HCs and 45 SLCs) were calculated on DWI. The differences in ADC values were analyzed by independent t-test. Results Of 51 patients, 28 were female, 23 were male (mean age 32.07 +/- 22.95 years; age range 5-82 years). Mean diameter of 45 SLCs was 2.59 +/- 1.23 cm (range 1.2-7.6 cm) and ADC(mean) value was 3.03 +/- 0.47 (range 2.64-5.85) while mean diameter of 50 type I HCs was 7.49 +/- 2.95 cm (range 2.8-14 cm) and ADC(mean) value was 2.99 +/- 0.29 (range 2.36-3.83). There was no statistically significant difference in ADC values between type I HCs and SLCs Conclusion Some studies report that ADC values of type I HCs are statistically significantly lower than those of SLCs. Others suggest no significant difference. In our study with a higher number of cases, using ADC parameters similar to those in previous studies, we did not find any statistically significant difference.
Evaluation of Celiac Disease With Uniphasic and Multiphasic Dynamic Mdct Imaging
(Springer, 2021) Goya, Cemil; Dundar, Ilyas; Ozgokce, Mesut; Turkoglu, Saim; Turko, Ensar; Ozkacmaz, Sercan; Almali, Necat
Purpose An analysis of dynamic contrast MRI has been shown to provide valuable information about disease activity in Crohn's disease and Celiac disease (CD). However, there are no reports of dynamic multi-detector computer tomography use in patients with CD. The aim of this study is to determine and compare the perfusion dynamics of the patients treated with control subjects and the perfusion dynamics in patients with untreated CD, using dynamic contrast in MDCT and compare studying contrast dynamics in Marsh types as well. Methods In this retrospective study, uniphasic and multiphasic MDCT, untreated, treated, incompatible CD patients and healthy control group duodenum wall thickness and HU values were compared in terms of patient groups and modified Marsh types. Result In dynamic CT, the highest contrast curve was observed in the untreated group and Marsh type 1. While the contrast curve of the untreated and non-compliant patients increased rapidly and showed wash out, the type 4 contrast curve was observed, whereas the treated and control group slowly increased type 5 contrast curve. In the contrast-enhanced CT in the venous phase, in the ROC analysis between Marsh 1-2 and Marsh 3a-c, the sensitivity was 97% and the specificity was 87% when the cut off was taken as 4.45 mm for wall thickness (p: 0.005). Conclusion Contrast-enhanced single-phase and dynamic MDCT imaging in CD patients may be useful in evaluating the inflammatory and pathological process in the small intestine. [GRAPHICS] .
Evaluation of Common Carotid and Vertebral Arteries Flow Volumes in Patients With Ankylosing Spondylitis
(Bayrakol Medical Publisher, 2020) Orak, Suat; Bora, Aydin; Yokus, Adem; Ozkacmaz, Sercan; Senkoy, Emre
Aim: The aim of this study was to compare carotid intima-media thickness (IMT) and common carotid artery-vertebral artery flow volumes in ankylosing spondylitis patients with age and sex-matched healthy controls. Materials and Methods: Fifty patients with ankylosing spondylitis (study group) and 50 healthy volunteers (control group) were included in the study. At first, carotid intima-media thickness (IMT) measurements were performed in supine-neutral position by B-mode ultrasonography (US). Afterwards, common carotid and vertebral artery flow volumes were calculated by Doppler US in the neutral, right rotational, and left rotational positions. Results: Carotid IMT was significantly higher in the study group according to the control group (p=0.001). The common carotid artery (CCA) and vertebral artery (VA) flow volumes in the neutral position were similar between the two groups. There was no significant difference in CCA flow volumes between the groups in right and left rotational positions (p>0.05). Right vertebral artery and total vertebral artery flow volumes in the right rotational position were significantly lower in the study group (p=0.022 and p=0.005 respectively). In the left rotational position, left vertebral artery and total vertebral artery flow volumes were significantly lower in the study group when compared with the control group (p=0.001). Discussion: In our study, carotid IMT was significantly higher in patients with AS compared to healthy controls. Besides, significant volume decreases in vertebral artery flow volumes were detected in the study group in rotational positions.
The Morphological Variants of Dural Venous Sinuses
(Wolters Kluwer Medknow Publications, 2020) Ozkacmaz, Sercan; Dadali, Yeliz; Alpaslan, Muhammed; Ucar, Ilyas
Introduction: In this study, we aimed to analyze the dural venous system variations in Turkey by magnetic resonance imaging examinations. Material and Methods: Images of a total of 200 patients (65 males, 135 females M/F: 0.48) who underwent a magnetic resonance venography examination were retrospectively screened. Results: Variation was detected in 101 patients (53.85% of males [35/65] and 48.89% of females [66/135]). In 16.5% of the patients, only one variation of dural venous system was detected, while the most common variation was left transverse hypoplasia in this group. Twenty-six percent of the patients had two variations of the dural venous system since the most common dual variations were left transverse hypoplasia + left sigmoid hypoplasia in this group. In 8% of the patients, three or more variations of the dural venous system were observed as the most common variations were right transverse hypoplasia + right sigmoid hypoplasia + presence of occipital sinus in this group. Discussion and Conclusion: It is essential to know the anatomical variations of the dural venous system for the discrimination between pathological processes such as thrombosis and physiologic conditions. Furthermore, the association of these variations with each other must be kept in mind for the explanation of the presence of multiple variations in the same individuals.