Browsing by Author "Ozturk, S."

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The Association of Visfatin Levels With Metabolic Parameters and Inflammation in Diabetic Nephropathy
(Yuzuncu Yil Universitesi Tip Fakultesi, 2020) Sakin, A.; Sahin, S.; Behlul, A.; Sumnu, A.; Gursu, M.; Sakin, A.; Ozturk, S.
To investigate the visfatin levels at the stages of diabetic nephropathy(DNP), changes in visfatin levels according to stages of DNP, and the association of visfatin levels with other anti-inflammatory parameters including high sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6), and tumor necrosis factor alpha(TNFα). Patients were divided into 4 groups based on the glomerular filtration rate (GFR) and albuminuria as follows; Group I: Albuminuria<30 mg per day and GFR>60ml/min, Group II:albuminuria 30 to 300 mg per day and GFR>60ml/min, Group III:albuminuria>300mg per day and GFR>60ml/min, and Group IV: Albuminuria>300 mg per day and GFR<60 ml/min. Of the 141 patients included in the study, 83(58.8%) were female. The mean age of patients was 55.3±8.2 years. Microalbuminuria was found to be 10.1±9.8 mg per day in group I, 89.4±68.2 mg per day in group II, 525.1±280.7 mg per day in group III, and 1034±1893 mg per day in group IV (p<0.001). When the correlation analysis was repeated separately in each group, there was a positive correlation between Visfatin and IL-6 levels in only group III (r=0.926; p<0.001). When the patients in group III and IV were combined in a single group and considered as macro-albuminuric, multivariate analysis showed that visfatin had a positive correlation with IL-6 (r=0.380, p=0.006) In this study, we could not determine any association between visfatin levels and other anti-inflammatory markers (IL-6, TNFα, and hsCRP). However, we found a close relationship between visfatin levels and IL-6 which is one of the most important markers of inflammation in diabetic patients with overt nephropathy, namely macro-albuminuric patients. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Basic Elements of the Traditional Garden Identity in the City of Van
(Academic Journals, 2010) Alp, S.; Ozturk, S.; Turkoglu, N.; Koyuncu, M.
Garden culture in the architectural patterns in and around the city of Van in the East Anatolian region of Turkey has been a tradition from the Urartian Iron Age Kingdom in Eastern Anatolia to the present. Until the end of the nineteenth century, the city of Van had an exclusive residential area where houses were surrounded by gardens. In this study, by exploring the texture of the old gardens in some current residential areas of the Van city center and its surroundings, we evaluated depending on the house-garden relationship, the street-house relationship, and size, garden elements, types of the plants. In this study the garden culture and understanding of the landscape will be brought from the time of the Urartians to our time and to the future. Further, an understanding of the traditional use of plant types in the city and their ornamental use will be recorded and perpetuated for regenerating into garden culture.
Evaluation of Essential Oil and Methanol Extracts of Thymus Kotschyanus for Chemical Compounds and Antibacterial Activity
(Chemical Publishing Co., 2006) Ozturk, S.; Ozturk, A.
The essential oils obtained from the aerial parts of Thymus kotschyanus were analyzed for chemical compounds by using GC and GC-MS. In addition, following the methanol extraction of aerial parts of Thymus kotschyanus, soluble fraction was tested for its antibacterial activity by using disc diffusion assay. Twenty-three components accounting for 98.34% of oil were identified. The main compounds were thymol (40.39%), carvacrol (28.15%), p-cymene (10.76%) and γ-terpinene (8.13%). The antibacterial activity results showed that methanol extract of Thymus kotschyanus had a great potential of antibacterial activity against 38 of 52 bacteria species, in particular, Arthrobacter atrocyaneus, Bacillus cereus, Bacillus flexus, Bacillus lentimorbis, Brevibacillus brevis, Erwinia chrysanthemi, Kocuria rosea, Micrococcus lylae, Paenibacillus macerans, Pantoea agglomerans, Pseudomonas syringae syringae, Staphylococcus cohnii cohnii, Xanthomonas arboricola carylina and methanol extract inhibited growth of these bacteria at the concentration of 15.60-500 μg/mL. The results suggest that Thymus kotschyanus represents an inexpensive source of natural mixtures of antibacterial compounds that exhibit potentials for use in food systems to prevent the growth of food-borne bacteria and extends the shelf life of the processed food.
Inhibition of Growth of Some Food Borne Bacteria by Falcaria Vulgaris Extract
(Chemical Publishing Co., 2006) Ozturk, S.; Ozturk, A.
Aerial parts of Falcaria vulgaris were successively extracted with methanol using a Soxhlet extractor, then the crude extract was screened for antibacterial activities. Extracts of Falcaria vulgaris were tested for their antibacterial activity in agar disk diffusion assays, whereas the minimum inhibitory concentrations (MIC) of single compounds were determined by the microbroth dilution method. Significant antibacterial activities were found against various strains, in particular Acidovorax facilis. Bacillus cereus, Bacillus dipsauri, Bacillus lentimorbus, Bacillus spp., Bacillus subtilis, Brevibacillus agri, Brevibacillus brevis, Corynebacterium ammoniagenes, Flavimonas oryzihabitans, Kocuria kristinae, Kocuria rosea, Micrococcus lylae, Paenibacillus apiarius, Paenibacillus macerans and Pseudomonas syringae syringae. These results support the ethnomedicinal use of Falcaria vulgaris both for treatment of infectious diseases and use as preservative in traditional herby cheese. This result may also suggest that the methanol extracts of Falcaria vulgaris possess compounds with antibacterial properties and thus can be used as a natural preservative ingredient in food and pharmaceutical industry.
A Statistical Analysis and Evaluation on the Earthquake Forecasting and Hazard for Lake Van and Its Adjacent Area (Türkiye)
(Afet ve Acil Durum Yonetimi Baskanligi (AFAD), 2022) Ozturk, S.; Alkan, H.
In this study, current earthquake hazard is tried to present and earthquake forecasting is made for Lake Van and its adjacent area for the next five years. For this purpose, a statistical analysis is achieved with the concomitant use of the b-value, Z-value, relative intensity (RI) and pattern informatics (PI) data. In addition, for the earthquake forecasting in the intermediate term and hazard, a comprehensive discussion is made with the studies analyzing the different seismological and geophysical variables in literature. The relations between these parameters reveal more accurate and reliable approaches. Consequently, at the beginning of 2022, particularly the areas having small b-value and large Z-value with the hotspots (possible earthquake areas) between 2022 and 2027 from the combined forecast map are determined in and around Muradiye, Çaldıran, Özalp, Van city centre and Gevaş including Çaldıran, Yeniköşk, Erciş and Malazgirt faults with Saray and Van Fault zones. © 2022 ARSMB-KVBMG. All rights reserved.