Browsing by Author "Parlar, A."

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Emd or Subepithelial Connective Tissue Graft for the Treatment of Single Gingival Recessions: a Pilot Study
(Wiley, 2011) Alkan, E. A.; Parlar, A.
Background and Objective: The combination of EMD with root-coverage procedures has been shown to promote periodontal regeneration on the exposed root surface. The aim of this randomized clinical study was to compare the efficacy of EMD with connective tissue graft (CTG) for the treatment of Miller Class I and Class II single recessions in a split-mouth design. Material and methods: The study included 12 systemically healthy patients, each with two single bilateral gingival recession defects (24 recessions). One recession defect in each patient was treated with the coronally advanced flap (CAF) + EMD procedure and the other recession defect was treated with the CTG + EMD procedure, in a split-mouth study design. The parameters recession depth (RD), recession width, percentage of root coverage, height of keratinized tissue (HKT), gingival thickness, probing depth and clinical attachment level (CAL) were recorded at baseline. All parameters, except for gingival thickness, were remeasured at 6 and 12 mo. Results: The mean percentage root coverage at the final evaluation was 92 +/- 14% for the CAF + EMD group and 89 +/- 14% for the CAF + CTG group. Both treatments resulted in statistically significant (p < 0.05) decreases in RD and recession width, and increases in HKT, at 6 and 12 mo. There was also a significant decrease in the probing depth and a significant gain in the CAL for both groups. The probing depth was statistically higher in the CAF + CTG group than in the CAF + EMD group at 6 mo (p < 0.05), while the CAL was statistically lower in the CAF + EMD group than in the CAF + CTG group at 6 and 12 mo (p < 0.05). Conclusion: The present study demonstrated that both CAF + EMD and CAF + CTG procedures were similarly successful in treating Miller Class I and Class II single gingival recession defects.
Enamel Matrix Derivative (Emdogain) or Subepithelial Connective Tissue Graft for the Treatment of Adjacent Multiple Gingival Recessions: a Pilot Study
(2013) Alkan, E.A.; Parlar, A.
One treatment approach for achieving healing by regeneration is the application of enamel matrix derivative (EMD) during periodontal surgery. The aim of this randomized clinical study was to compare the efficacy of EMD with a connective tissue graft (CTG) for the treatment of adjacent Miller Class l and II multiple gingival recessions. Twelve systemically healthy subjects with at least two Miller Class I or II multiple gingival recession defects affecting adjacent teeth on both sides of the mouth were enrolled. The surgical protocol was performed for both groups. The 56 recession defects were evaluated for recession depth (RD), recession width (RW), percentage of root coverage (PRC), height of keratinized tissue (HKT), probing depth (PD), and clinical attachment level (CAL). All measurements were repeated at 6 and 12 months. The mean PRC at the final evaluation was 89% ± 17% for the coronally advanced flap (CAF) + EMD group and 93% ± 17% for the CAF + CTG group. Both treatments resulted in statistically significant decreases in RD and RW and increases in HKT at 6 and 12 months. There was also a significant CAL gain for both groups. PD remained shallow over time. The results demonstrated that both procedures were successful in treating Miller Class I and II multiple gingival recessions; however, the greater results of the CAF + CTG group did not reach a statistically significant level. © 2013 by Quintessence Publishing Co Inc.
Histological Comparison of Healing Following Tooth Extraction With Ridge Preservation Using Enamel Matrix Derivatives Versus Bio-Oss Collagen: a Pilot Study
(Churchill Livingstone, 2013) Alkan, E. A.; Parlar, A.; Yildirim, B.; Senguven, B.
The goal of the present clinical study was to evaluate new bone formation in human extraction sockets augmented with enamel matrix derivatives (EMD) and Bio-Oss Collagen. Patients with symmetrical single-rooted teeth in the bilateral quadrants of the upper jaw condemned for extraction participated in this study. Following extraction, the sockets (20 sockets) were randomly augmented using either EMD or Bio-Oss Collagen. After 3 months of healing, bone biopsies were obtained and prepared for histological analyses. Dental implants were then placed. Implant stability quotient (ISQ) readings were obtained for each implant at the time of surgery and at 1 and 3 months postoperatively. The mean new bone formation was 34.57 +/- 25.67% in the EMD sites and 28.80 +/- 16.14% in the Bio-Oss Collagen sites. There was no significant difference between the groups. The ISQ values were significantly higher for the implants placed in the EMD sites at the first and third months, but no significant differences were observed in the ISQ values for the implants placed in the Bio-Oss Collagen sites. The augmentation of the extraction sockets with EMD or Bio-Oss Collagen leads to similar behaviour in bone regeneration.