Browsing by Author "Pirincci, N."

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Can Cancer Detection Rate Increase When Transrectal Biopsies Were Taken From the Laterally
(Yuzuncu Yil Universitesi Tip Fakultesi, 2014) Karakose, A.; Yuksel, M.B.; Pirincci, N.; Gorgel, S.N.; Atesci, Y.Z.; Gumus, B.
Acording to general opinion when biopsy is taken from the prostate’s lateral peripheral zone. More cancer is seen. In our study, the incidence of cancer in the lateral peripheral zone biopsies was investigated. In our study, 93 patients were analyzed retrospectively transrectal prostate biopsy. 12 core biopsies were taken from each patient. Medial peripheral zone (MPZ) and lateral peripheral zone (LPZ) biopsies compared the detection of prostate cancer. The average age of the patients was 67.2±10.3. Total PSA value in patients was found as 13.7 ng/mL. Prostate cancer was detected at the rate of 22.5% (21 patients) in 93 patients. 3 patients (14.3%) had prostate cancer in MPZ and 8 patients (38%) had prostate cancer in LPZ. Prostate cancer was detected at MPZ and LPZ at the rate of 47.7% (10 patients) in patients. Prostate cancer was more commonly detected in LPZ (p<0.05). Prostate biopsies of the LPZ biopsies more commonly cancer is seen. We believe it will increase the capture rate for prostate cancer if a sufficient number of biopsies were taken from the LPZ. © 2014, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Can Renal Infarction Occur After Renal Cyst Aspiration? Case Report
(2011) Emre, H.; Soyoral, Y.U.; Tanik, S.; Gecit, I.; Begenik, H.; Pirincci, N.; Erkoc, R.
Renal infarction (RI) is a rarely seen disorder, and the diagnosis is often missed. The two major causes of RI are thromboemboli originhating from a thrombus in the heart or aorta, and in-situ thrombosis of a renal artery. We report a case of RI that developed due to renal artery and vein thrombosis, as confirmed by pathological evaluation of the nephrectomy material, three weeks after renal cyst aspiration.
Can Retrovert Uterus Be a Cause of Recurrent Temporal Acute Urinary Retention During Pregnancy
(TIP ARASTIRMALARI DERNEGI, 2013) Geçit, I.; Benli, E.; Güneş, M.; Pirincci, N.; Kurdoǧlu, Z.; Eren, H.
Urinary retention developing in early period of pregnancy is a rare but urgent condition. A few literatures were encountered on this issue. Retrovert uterus, endometriosis, pelvic inflammatory event-related adhesions, ectopic pregnancy and intramural myomas are among predisposing factors. These factors cause stucking of uterus in pelvic cavity by hindering elevation of uterus in the abdomen and acute urinary retention may develop as the result of pressure to urinary bladder floor and urethra The case who developed the urinary retention in her three sequential pregnancies has been discussed in the light of the literature in this paper.
Comparison of Cystoscopy With Diffusion-Weighted Magnetic Resonance Images Used in the Diagnosis and Follow-Up of Patients With Bladder Tumor
(Elsevier Science Bv, 2010) Ceylan, K.; Taken, K.; Gecit, I; Pirincci, N.; Gunes, M.; Karaman, M.
Do the Medical Treatment Reduces the Rate of Surgical Treatment in Suspected Cases of Chronic Prostatitis Before Prostatectomy
(verduci Publisher, 2013) Gunes, M.; Gecit, I.; Pirincci, N.; Cecen, K.; Taken, K.; Ceylan, K.; Ozunver, H.
AIM: Our aim is to investigate how the chronic intraprostatic inflammation affect the course of the BPH (benign prostatic hyperplasia). PATIENTS AND METHODS: Between the dates of 2007-2011, the files of the patients who had TUR-P (transurethral resection of the prostate) and underwent open surgery were retrospectively reviewed because of BPH, and the patients were divided into two groups who were operated due to AUR (acute urinary retention) or LUTS (lower urinary tract symptoms) and the clinical data and pathology results of the two groups were compared in terms of chronic intraprostatic inflammation. RESULTS: There were evaluable data of 130 of 150 patients. The age range of the patients was 50-88. 52 of the 130 patients due to AUR and 78 of them due to LUTS underwent surgery. While there was chronic inflammation in 59 of the 130 patients, there was not in 71. The volume of the prostate and the average age of those who had chronic prostatitis with the combination of AUR were greater compared to the LUTS. CONCLUSIONS: It seems that chronic prostatitis is a factor which is often accompanied by BPH and affects the progression and pathology of the disease. The risk of acute urinary retention is more frequent in patients with chronic inflammation than in those who lack. In the future, related clinical trials with the relationship between the intraprostatic inflammation and BPH treatment are necessary and should include more cases and longer period of follow-up for these studies.
The Effect of Antibiotherapy on High Serum Psa Levels
(Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Karakose, A.; Yuksel, M.B.; Pirincci, N.; Gorgel, S.N.; Atesci, Y.Z.; Gumus, B.
This study investigated the effect of antibiotics in patients with PSA value high than 4 ng/mL on tPSA, fPSA and fPSA/tPSA ratio without missing cancer and avoiding unnecessary biopsies. A total of 96 patients were included into the study with detected high level than 4 ng/mL serum PSA. Patients were divided into 2 groups according to the high level of PSA value. Group 1 included 49 patients with PSA level between 4-10 ng/mL. Group 2 included 47 patients with PSA level higher than 10 ng/mL. Patients were treated with Ciprofloxacin (500mg b.i.d.) orally for 2 weeks. All patients' PSA levels were evaluated and analyzed before and after antibiotic treatment. Statistical analyses were performed with SPSS version 18. A p value <0.05 was considered as significant. The mean age was 61.6 ±5.7 (51-75) years in group 1 and 63.1 ±8.7 (55-74) years in group 2. Suspicious DRE findings were significantly high in group 2. The mean tPSA values were 6.82±0.42 and 5.93±0.36 before and after antibiotic treatment in group 1 respectively. There was no significant differences in tPSA value before and after antibiotic treatment in group 1. The mean tPSA values were 32.53±8.23 and 11.72±5.61 before and after antibiotic treatment in group 2 respectively. The mean tPSA value decreased significantly after antibiotic treatment in group 2. Prostate cancer was detected in 32 patients after TRUS guided prostate biopsy. Prostate cancer was identified in 13 patients in group 1 and 19 patients in group 2. Antibiotic treatment in patients with PSA levels higher than 10 ng/mL is effective on prostate biopsy decision and antibiotic treatment can prevent unnecessary prostate biopsies. © 2015 Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
The Effectiveness of Extracorporeal Shock Wave Lithotripsy in the Treatment of Ureteral Stones in Children
(verduci Publisher, 2012) Pirincci, N.; Gecit, I.; Bilici, S.; Taken, K.; Tanik, S.; Ceylan, K.
PURPOSE: In our study, we evaluated retrospectively the efficacy of extracorporeal shock wave lithotripsy (ESWL) in the treatment of ureteral stones in children. MATERIALS AND METHODS: Between the dates of 2005-2010, 62 children who were applied ESWL due to the ureteral stone in our Clinic and consisted of 42 males and 20 girls whose mean age was 6.6 +/- 3.1 were evaluated. 31(50%) of the patients were upper ureteral stone, 10 (16.1%) of them were middle ureteral stone and 21(33.9%) of them were lower ureteral stone. The sizes of the stones were 4 to 17 mm, the average was 7.1 mm. ESWL was performed in the supine position for upper ureteral stones, in the supine/prone position for middle and lower ureteral stones. RESULTS: Stone-free rate was determined as 93.5% in three-month follow-up of the patients. Re-treatment was done at 14.5% of the patients. The implementation of ESWL was ended unsuccessfully at 4 children (6.5%). A significant difference was not detected between three-month stone-free rates in terms of the size of the stones and location. There was not any serious complication at any of the patients. CONCLUSIONS: According to these findings ESWL with its high stone-free rates and negligible complications is the first method to be refered in the treatment of ureteral stones in children.
Histopathological Changes That Occur on the Testicular and Penile Tissues Depending on the Treatment of Human Chorionic Gonadotropin: Rat Model
(Univ West indies Faculty Medical Sciences, 2021) Pirincci, N.; Yildirim, S.; Tas, A.; Ozan, T.; Gecit, I; Ozveren, H.
Objective: To examine the histopathological effects of human chorionic gonadotropin (hCG) treatment on the penile and the testicular tissue in rat model. Methods: The rats of the hCG group (n = 8) were given daily subcutaneous injections of 50 IU of hCG for 15 days (Pregnyl, Organon). Rats of the control group (n = 8) received subcutaneous isotonic saline. All rats were sacrificed at the 1st month after hCG administration. After the received tissue samples were examined, germinal epithelial cell thickness, seminiferous tubule diameter; internal diameter of the tubules, the number of germ cell layers in the testicular tissue, and the diameters of penis, cavernous sinus lumen diameters and collagen tissue amount in the cavernous sinus surrounding were assessed in the sections prepared from the penis. Results: It was detected that there was a decrease in the testis weight, atrophy in the tubules, reduction in spermatogenesis, decrease in the mature spermatocytes, lower mean thickness and the number of cell layers of the germinal membrane in testicular tissue in the hCG group. It was found that the amount of collagen in the penile tissue was significantly higher in the hCG group and the diameters of cavernosal sinus lumens, and diameter of the penis were significantly lower in the hCG group. Conclusion: Human chorionic gonadotropin led to the deterioration in testicular histology and the histological changes in the penile tissue. The degradation in the testicular tissue and these changes formed in the penile tissue may affect the erectile tissue function.
Laparoscopic Transperitoneal Nephrectomy in Non-Functioning Inflammatory Kidneys With or Without Renal Stone
(verduci Publisher, 2015) Kaba, M.; Pirincci, N.; Taken, K.; Gecit, I.; Demiray, O.; Eren, H.
OBJECTIVE: To compare our laparoscopic simple nephrectomy results in non-functioning inflammatory kidneys with or without renal stones. PATIENTS AND METHODS: Patients, who underwent laparoscopic transperitoneal nephrectomy for non-functioning kidney between June, 2010 and October, 2014 were included to study. Overall, data of 32 patients including 15 patients with renal stone (Group 1) and 17 patients without renal stone (Group 2) were retrospectively reviewed. RESULTS: Mean age was 44.4 +/- 18.5 years (10-71) in group 1 and 35.2 +/- 21 years (9-77) in group 2. Mean operation time was 95.0 +/- 25.9 minutes (70-175) in group 1 and 86.7 +/- 15.1 minutes (70-125) in group 2. Mean estimated blood loss was found to be 64.13 +/- 26.67 ml (30-120) in group 1 and 58.94 +/- 24.24 ml (30-100) in group 2. Both groups had inflammatory findings in pathological analysis. There was no significant difference between groups regarding estimated blood loss, operation time, pre-operative and post-operative hemoglobin values, percent hemoglobin decrease, complications and hospitalization times (p > 0.05). CONCLUSIONS: Non-functioning kidney with or without renal stone could be operated safely with comparable complication rates and success via laparoscopy in experienced hands.
Modified Raz Operation Backed With Periurethral Roll Mesh in Female Stress Urinary Incontinence
(verduci Publisher, 2012) Pirincci, N.; Kamberoglu, H.; Kaya, C.; Kaba, M.; Gecit, I.; Gunes, M.; Karaman, M. I.
OBJECTIVES: With the modifications that we made, the aim is to increase the effectiveness and the success rate of the Raz operation in the treatment of stress urinary incontinence (SUI) and to present a new approach in the treatment by reducing the complication rates. PATIENTS AND METHODS: Between November 2002 and December 2010, the Raz operation that we modified with the changes such as the placement of cystostomy catheter with the Lowsley clamp, vaginal incision of the bilateral oblique, the placement of periurethral roll mesh, the use of a single 0-degree stamey needle instead of a double needle applicator, binding the sutures mutually and on the support of the polypropylene mesh in suprapubic region was performed to 81 female patients with SUI in lithotomy position under the regional anesthesia. RESULTS: We performed the modified Raz operation to 81 female patients with SUI, who had the complaint of urinary incontinence with the effort lasting for about 4.5 years (between 1-16 years) and whose ages were 28-83 years (mean 55.2 years), childbirth numbers were 0-11 (mean 4.8), weights were 60-85 kg (mean 69.3 kg), and 32 of whom (39.5%) were of grade 1, 49 of whom (60.5%) were of grade 2 with the anamnesia of SUI, and whose stres test was (+) in the physical examination. While the duration of the operation was 39.8 minutes (20-85 minutes) and the duration of the hospitalization was 2.9 days (2-4 days), the duration of the stay of the patients with the cystostomy catheter was determined to be 4.8 days (3-11 days). We found the rate of our success as 93.8% according to the objective criteria. CONCLUSIONS: With the modifications that we made, we increased the success rate of the Raz operation and reduced the rates of the complication. We believe that the place of our modification method in incontinence surgery becomes more clearly with the comparison of the other anti-incontinence surgery techniques in patient groups with the same characteristics.
Should Ureteroscopy Be Considered as the First Choice for Proximal Ureter Stones of Children
(verduci Publisher, 2013) Gecit, I.; Pirincci, N.; Gunes, M.; Bilici, S.; Taken, K.; Goktas, U.; Ceylan, K.
OBJECTIVES: In this study, we aimed to analyze the ureter stones that had been treated using rigid ureteroscopy and pneumatic lithotripsy without mechanically dilating the ureteral orifice. PATIENTS AND METHODS: Records of 110 patients who had undergone rigid ureteroscopy and pneumatic lithotripsy due to ureteral stone between February 2005 and May 2011 were retrospectively analyzed. The location and size of the stone and additional anomalies in the urinary tract on the preoperative direct urinary system (DUS) X-Ray, urinary system ultrasonography (USG), intravenous pyelography (IVP) if performed, and computed tomography (CT), were found from the records of the patients. RESULTS: The mean age of the patients was 5.2 (range 1-17 years). 74 (67.2%) of the patients were males and 36 (32.8%) were females. A total of 115 rigid ureteroscopies were performed on 110 patients. 72 (65%) of the stones were located in the lower ureter, 21 (19%) were located in the middle part of the ureter, and 17 (15.4%) were located in the upper ureter. The mean stone size was determined as 7.5 mm (range 5-15). The mean stone size was determined as 7.4 mm in the lower ureter, as 8.3 mm in the middle ureter, and 8.4 mm in the upper ureter. No difference was found between the sizes of the stones in different locations (p = 0.121). The stone free rate was found as 92.2% for all ureteral stones. The total stone free rate according to the location of the stones was determined as 79.2% in the upper ureter, as 94.4% in the middle ureter and 93,8% in the lower ureter (p = 0.022). The total complication rate was 7.6%. Complication rates were 7.2%, 4.1% and 10.7% for the lower, middle and upper ureter, respectively (p = 0.411) (Table I). No difference was found in terms of complication rates according to location of the stone in the ureter. No major perioperative or postoperative complications developed. A double J stent was inserted in 36 (32%) patients for 2-3 weeks. CONCLUSIONS: We suggest that rigid ureteroscopy may be considered as the first choice for treatment of not only distal-middle ureter stones, but also for proximal ureter stones.
Uretherorenoscopic Stone Therapy in Children: Our 5 Years of Experience
(Elsevier Science Bv, 2010) Gecit, I; Pirincci, N.; Taken, K.; Bilici, S.; Goktas, U.; Tanik, S.; Ceylan, K.
Uretheroscopy Pneumatic Lithotripsy Approach in Ureter Stones and Its Results: Our 5 Years of Experiences
(Elsevier Science Bv, 2010) Gecit, I; Pirincci, N.; Taken, K.; Benli, E.; Yamis, S.; Tanik, S.; Ceylan, K.